SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6etz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMI_A_BHSA1610_1
(NITRIC OXIDE
SYNTHASE)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		4 / 8 ARG A  67
ALA A 191
PHE A  89
GLU A  84
 None
 1.07A 1dmiA-6etzA:
undetectable
1dmiB-6etzA:
undetectable		 1dmiA-6etzA:
10.99
1dmiB-6etzA:
10.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA206_1
(CARDIAC TROPONIN C)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		4 / 8 PRO A 903
GLU A 910
ASP A 908
ARG A 947
 None
 1.22A 1dtlA-6etzA:
undetectable		 1dtlA-6etzA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IIU_A_RTLA176_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		5 / 11 LEU A 327
LEU A 542
ALA A 486
ALA A 489
GLN A 533
 None
 1.40A 1iiuA-6etzA:
undetectable		 1iiuA-6etzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JKH_A_EFZA999_1
(HIV-1 RT, A-CHAIN
HIV-1 RT, B-CHAIN)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		5 / 11 LEU A 930
VAL A1008
GLY A 749
LEU A 928
GLU A 872
 None
 1.47A 1jkhA-6etzA:
undetectable
1jkhB-6etzA:
undetectable		 1jkhA-6etzA:
8.76
1jkhB-6etzA:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIN_A_TFPA155_1
(CALMODULIN)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		4 / 7 GLN A 196
GLU A 153
MET A 100
ALA A 105
 None
 1.33A 1linA-6etzA:
undetectable		 1linA-6etzA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MIC_A_DVAA6_0
(GRAMICIDIN A)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		3 / 3 ALA A 431
VAL A 433
TRP A 436
 None
 0.78A 1micA-6etzA:
undetectable
1micB-6etzA:
undetectable		 1micA-6etzA:
undetectable
1micB-6etzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RLB_E_REAE176_1
(RETINOL BINDING
PROTEIN)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		5 / 10 LEU A 620
ALA A 688
VAL A 663
ASP A 628
GLN A 624
 None
 1.24A 1rlbE-6etzA:
undetectable		 1rlbE-6etzA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_D_DESD600_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		5 / 12 LEU A1006
LEU A 842
VAL A 829
TYR A 831
ILE A 937
 None
 1.09A 1s9pD-6etzA:
undetectable		 1s9pD-6etzA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T9W_A_NFNA6002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		4 / 7 GLN A 196
ALA A 107
PHE A 115
GLU A 153
 None
 1.02A 1t9wA-6etzA:
undetectable		 1t9wA-6etzA:
5.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_A_CRNA401_1
(CREATININE
AMIDOHYDROLASE)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		4 / 8 HIS A 959
ASP A 571
TYR A 108
TRP A 209
 None
 0.90A 1v7zA-6etzA:
undetectable		 1v7zA-6etzA:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_B_CRNB3401_1
(CREATININE
AMIDOHYDROLASE)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		4 / 8 HIS A 959
ASP A 571
TYR A 108
TRP A 209
 None
 0.91A 1v7zB-6etzA:
undetectable		 1v7zB-6etzA:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_C_CRNC4401_1
(CREATININE
AMIDOHYDROLASE)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		4 / 8 HIS A 959
ASP A 571
TYR A 108
TRP A 209
 None
 0.90A 1v7zC-6etzA:
undetectable		 1v7zC-6etzA:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_D_CRND5401_1
(CREATININE
AMIDOHYDROLASE)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		4 / 8 HIS A 959
ASP A 571
TYR A 108
TRP A 209
 None
 0.90A 1v7zD-6etzA:
undetectable		 1v7zD-6etzA:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_E_CRNE6401_1
(CREATININE
AMIDOHYDROLASE)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		4 / 8 HIS A 959
ASP A 571
TYR A 108
TRP A 209
 None
 0.89A 1v7zE-6etzA:
undetectable		 1v7zE-6etzA:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_F_CRNF7401_1
(CREATININE
AMIDOHYDROLASE)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		4 / 8 HIS A 959
ASP A 571
TYR A 108
TRP A 209
 None
 0.91A 1v7zF-6etzA:
undetectable		 1v7zF-6etzA:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_C_ADNC2502_2
(ADENOSYLHOMOCYSTEINA
SE)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		3 / 3 GLU A 393
THR A 394
LEU A 448
 None
 0.71A 1v8bC-6etzA:
undetectable		 1v8bC-6etzA:
9.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XID_A_ASCA389_0
(D-XYLOSE ISOMERASE)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		5 / 10 TRP A 548
HIS A 334
GLU A 393
GLU A 441
HIS A 395
 None
 1.41A 1xidA-6etzA:
3.4		 1xidA-6etzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_A_ADNA433_2
(ADENOSYLHOMOCYSTEINA
SE)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		3 / 3 THR A 444
GLU A 467
HIS A 395
 None
 0.48A 1xwfA-6etzA:
undetectable		 1xwfA-6etzA:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_B_ADNB433_2
(ADENOSYLHOMOCYSTEINA
SE)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		3 / 3 THR A 444
GLU A 467
HIS A 395
 None
 0.50A 1xwfB-6etzA:
undetectable		 1xwfB-6etzA:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_C_ADNC433_2
(ADENOSYLHOMOCYSTEINA
SE)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		3 / 3 THR A 444
GLU A 467
HIS A 395
 None
 0.50A 1xwfC-6etzA:
undetectable		 1xwfC-6etzA:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_D_ADND433_2
(ADENOSYLHOMOCYSTEINA
SE)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		3 / 3 THR A 444
GLU A 467
HIS A 395
 None
 0.45A 1xwfD-6etzA:
undetectable		 1xwfD-6etzA:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYU_B_SAMB201_1
(PUTATIVE RIBOSOMAL
RNA
METHYLTRANSFERASE 2)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		4 / 5 PRO A 780
ALA A 782
ASP A 777
ASP A 787
 None
 0.80A 2nyuB-6etzA:
undetectable		 2nyuB-6etzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		4 / 6 ILE A 864
ARG A 863
LEU A 758
LEU A 995
 None
 1.06A 2rlfA-6etzA:
undetectable
2rlfD-6etzA:
undetectable		 2rlfA-6etzA:
19.44
2rlfD-6etzA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_C_BEZC1222_0
(PEROXIREDOXIN 6)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		4 / 7 THR A 835
VAL A 721
GLU A 838
PRO A 718
 None
 1.04A 2v2gC-6etzA:
undetectable
2v2gD-6etzA:
undetectable		 2v2gC-6etzA:
undetectable
2v2gD-6etzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V3D_A_NBVA1503_1
(GLUCOSYLCERAMIDASE)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		6 / 12 ASP A 207
ASN A 440
TYR A 482
GLU A 517
TRP A 548
ASN A 110
 NA  A1105 (-2.6A)
None
None
None
None
None
 1.23A 2v3dA-6etzA:
13.2		 2v3dA-6etzA:
12.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V3D_B_NBVB1504_1
(GLUCOSYLCERAMIDASE)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		6 / 11 ASP A 207
ASN A 440
TYR A 482
GLU A 517
TRP A 548
ASN A 110
 NA  A1105 (-2.6A)
None
None
None
None
None
 1.29A 2v3dB-6etzA:
11.1		 2v3dB-6etzA:
12.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_L_ASDL1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		4 / 7 PRO A 371
LEU A 376
ALA A 379
PHE A 384
 None
 0.97A 2vcvL-6etzA:
undetectable		 2vcvL-6etzA:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDY_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		5 / 12 SER A  59
THR A 168
ILE A 214
PHE A 149
HIS A 175
 ACT  A1104 (-4.6A)
None
None
None
None
 1.43A 2vdyA-6etzA:
undetectable		 2vdyA-6etzA:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_B_DIFB1376_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		4 / 7 TYR A 292
GLY A 236
ALA A 235
LEU A 246
 None
 0.83A 2wekB-6etzA:
undetectable		 2wekB-6etzA:
12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XIN_A_SORA397_0
(D-XYLOSE ISOMERASE)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		5 / 12 TRP A 548
HIS A 334
GLU A 393
GLU A 441
HIS A 395
 None
 1.47A 2xinA-6etzA:
10.3		 2xinA-6etzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XIN_B_SORB397_0
(D-XYLOSE ISOMERASE)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		5 / 12 TRP A 548
HIS A 334
GLU A 393
GLU A 441
HIS A 395
 None
 1.43A 2xinB-6etzA:
9.9		 2xinB-6etzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XIN_C_SORC397_0
(D-XYLOSE ISOMERASE)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		5 / 12 TRP A 548
HIS A 334
GLU A 393
GLU A 441
HIS A 395
 None
 1.45A 2xinC-6etzA:
10.0		 2xinC-6etzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XIN_D_SORD397_0
(D-XYLOSE ISOMERASE)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		5 / 12 TRP A 548
HIS A 334
GLU A 393
GLU A 441
HIS A 395
 None
 1.43A 2xinD-6etzA:
10.1		 2xinD-6etzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7W_B_SALB1300_1
(LYSR-TYPE REGULATORY
PROTEIN)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		5 / 10 GLY A 569
PHE A 572
GLY A 554
HIS A 959
THR A 583
 None
 1.31A 2y7wB-6etzA:
undetectable		 2y7wB-6etzA:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUL_A_SAMA376_0
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		5 / 12 GLY A 981
GLY A 979
ASN A 524
PRO A 526
VAL A 519
 None
 1.08A 2zulA-6etzA:
undetectable		 2zulA-6etzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A2Q_A_ACAA602_1
(6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		4 / 7 ASN A 622
ALA A 688
ALA A 704
GLN A 624
 None
 0.70A 3a2qA-6etzA:
undetectable		 3a2qA-6etzA:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_A_CRNA303_1
(CREATININE
AMIDOHYDROLASE)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		4 / 8 HIS A 959
ASP A 571
TYR A 108
TRP A 209
 None
 0.95A 3a6jA-6etzA:
undetectable		 3a6jA-6etzA:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_E_CRNE306_1
(CREATININE
AMIDOHYDROLASE)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		4 / 8 HIS A 959
ASP A 571
TYR A 108
TRP A 209
 None
 0.96A 3a6jE-6etzA:
undetectable		 3a6jE-6etzA:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AF0_A_PAUA314_0
(PANTOTHENATE KINASE)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		4 / 8 ASP A 890
LEU A 990
GLY A 988
TYR A 532
 None
 0.99A 3af0A-6etzA:
undetectable		 3af0A-6etzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6R_B_CRNB603_1
(CREATINE KINASE
B-TYPE)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		4 / 6 THR A 934
VAL A1008
LEU A 930
GLU A 872
 None
 1.20A 3b6rB-6etzA:
undetectable		 3b6rB-6etzA:
16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CCF_A_BEZA261_0
(CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		4 / 8 HIS A 885
GLY A 892
TRP A 879
PHE A 900
 None
 1.40A 3ccfA-6etzA:
undetectable		 3ccfA-6etzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DMF_A_SAMA388_0
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		5 / 12 GLY A 981
GLY A 979
ASN A 524
PRO A 526
VAL A 519
 None
 1.11A 3dmfA-6etzA:
undetectable		 3dmfA-6etzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DMH_A_SAMA384_0
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		5 / 12 GLY A 981
GLY A 979
ASN A 524
PRO A 526
VAL A 519
 None
 1.07A 3dmhA-6etzA:
undetectable		 3dmhA-6etzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HRD_E_NIOE5660_1
(NICOTINATE
DEHYDROGENASE LARGE
MOLYBDOPTERIN
SUBUNIT
NICOTINATE
DEHYDROGENASE MEDIUM
MOLYBDOPTERIN
SUBUNIT)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		3 / 3 GLU A 441
GLU A 393
TRP A 548
 None
 0.89A 3hrdA-6etzA:
undetectable
3hrdE-6etzA:
undetectable
3hrdF-6etzA:
undetectable		 3hrdA-6etzA:
12.47
3hrdE-6etzA:
12.47
3hrdF-6etzA:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HZN_G_ACTG225_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		3 / 3 PRO A 780
LEU A 781
GLN A 784
 None
 0.73A 3hznG-6etzA:
undetectable
3hznH-6etzA:
undetectable		 3hznG-6etzA:
undetectable
3hznH-6etzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1101_0
(STRUCTURAL PROTEIN
VP3)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		5 / 12 PRO A 371
GLY A 170
ARG A 422
ARG A 169
ILE A 152
 None
None
ACT  A1101 ( 4.3A)
None
None
 1.45A 3jb2A-6etzA:
undetectable		 3jb2A-6etzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_A_THHA642_1
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		3 / 3 ASN A 791
ASP A 955
ARG A 771
 None
 0.92A 3k13A-6etzA:
6.3		 3k13A-6etzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_2
(GENOME POLYPROTEIN)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		4 / 4 PHE A 546
TYR A 385
VAL A 587
LEU A 551
 None
 1.11A 3keeD-6etzA:
undetectable		 3keeD-6etzA:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_A_AICA375_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		5 / 11 GLY A 647
LEU A 684
ARG A 710
LEU A 672
LEU A 665
 None
 1.39A 3ndvA-6etzA:
undetectable
3ndvB-6etzA:
undetectable		 3ndvA-6etzA:
12.87
3ndvB-6etzA:
12.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_B_AICB376_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		5 / 11 LEU A 665
GLY A 647
LEU A 684
ARG A 710
LEU A 672
 None
 1.38A 3ndvA-6etzA:
undetectable
3ndvB-6etzA:
undetectable		 3ndvA-6etzA:
12.87
3ndvB-6etzA:
12.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_C_AICC375_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		5 / 11 GLY A 647
LEU A 684
ARG A 710
LEU A 672
LEU A 665
 None
 1.40A 3ndvC-6etzA:
undetectable
3ndvD-6etzA:
undetectable		 3ndvC-6etzA:
12.87
3ndvD-6etzA:
12.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_D_AICD374_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		5 / 11 LEU A 665
GLY A 647
LEU A 684
ARG A 710
LEU A 672
 None
 1.40A 3ndvC-6etzA:
undetectable
3ndvD-6etzA:
undetectable		 3ndvC-6etzA:
12.87
3ndvD-6etzA:
12.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SP9_A_IL2A901_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		5 / 12 ILE A 152
LEU A  35
VAL A 122
ILE A 128
HIS A 131
 None
 1.25A 3sp9A-6etzA:
undetectable		 3sp9A-6etzA:
13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_A_SAMA300_0
(PUTATIVE
METHYLTRANSFERASE)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		5 / 12 GLN A 707
GLY A 883
GLY A 898
SER A 921
ALA A 895
 None
 1.27A 3t7sA-6etzA:
undetectable		 3t7sA-6etzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_C_SAMC300_0
(PUTATIVE
METHYLTRANSFERASE)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		5 / 12 GLN A 707
GLY A 883
GLY A 898
SER A 921
ALA A 895
 None
 1.28A 3t7sC-6etzA:
undetectable		 3t7sC-6etzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TMZ_A_06XA503_1
(CYTOCHROME P450 2B4)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		5 / 11 ILE A 307
PHE A 309
ALA A 294
GLU A 269
VAL A 248
 None
 1.02A 3tmzA-6etzA:
undetectable		 3tmzA-6etzA:
12.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U7S_A_017A202_2
(POL POLYPROTEIN)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		5 / 9 GLY A 643
ALA A 640
ASP A 641
GLY A 898
LEU A 684
 None
 0.99A 3u7sB-6etzA:
undetectable		 3u7sB-6etzA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UA5_B_06XB501_1
(CYTOCHROME P450 2B6)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		4 / 7 ILE A 937
GLU A 867
LEU A 870
VAL A 753
 None
 0.73A 3ua5B-6etzA:
undetectable		 3ua5B-6etzA:
11.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V35_A_NTIA317_1
(ALDOSE REDUCTASE)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		4 / 8 TRP A 210
PHE A 115
PRO A 406
TRP A 412
 None
 1.30A 3v35A-6etzA:
7.8		 3v35A-6etzA:
14.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3O_B_T1CB405_1
(TETX2 PROTEIN)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		5 / 12 HIS A 131
GLY A 213
PRO A 127
GLY A  71
GLU A 124
 None
 1.23A 3v3oB-6etzA:
undetectable		 3v3oB-6etzA:
11.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V81_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		4 / 8 LEU A 866
VAL A 846
TRP A 833
LEU A 756
 None
 1.10A 3v81C-6etzA:
undetectable		 3v81C-6etzA:
9.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VQR_A_ACTA1002_0
(PUTATIVE
OXIDOREDUCTASE)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		4 / 6 GLY A 981
VAL A 989
ASP A 890
THR A 891
 None
 1.15A 3vqrA-6etzA:
undetectable		 3vqrA-6etzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VQR_B_ACTB1002_0
(PUTATIVE
OXIDOREDUCTASE)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		4 / 5 GLY A 981
VAL A 989
ASP A 890
THR A 891
 None
 1.14A 3vqrB-6etzA:
undetectable		 3vqrB-6etzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VT7_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		5 / 12 VAL A 343
ARG A 216
SER A 171
HIS A 101
LEU A  92
 None
 1.48A 3vt7A-6etzA:
undetectable		 3vt7A-6etzA:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3XIM_B_SORB397_0
(D-XYLOSE ISOMERASE)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		5 / 12 TRP A 548
HIS A 334
GLU A 393
GLU A 441
HIS A 395
 None
 1.45A 3ximB-6etzA:
5.3		 3ximB-6etzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3XIM_D_SORD397_0
(D-XYLOSE ISOMERASE)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		5 / 12 TRP A 548
HIS A 334
GLU A 393
GLU A 441
HIS A 395
 None
 1.44A 3ximD-6etzA:
10.0		 3ximD-6etzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6N_B_T1CB392_1
(TETX2 PROTEIN)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		5 / 11 HIS A 131
GLY A 213
PRO A 127
GLY A  71
GLU A 124
 None
 1.20A 4a6nB-6etzA:
undetectable		 4a6nB-6etzA:
11.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AQ7_A_LEUA902_0
(LEUCINE--TRNA LIGASE)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		4 / 7 ASP A 459
SER A 461
GLU A 249
HIS A 234
 None
 1.17A 4aq7A-6etzA:
undetectable		 4aq7A-6etzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		5 / 12 SER A  59
THR A 168
ILE A 214
PHE A 149
HIS A 175
 ACT  A1104 (-4.6A)
None
None
None
None
 1.33A 4c49B-6etzA:
undetectable		 4c49B-6etzA:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FUB_A_ACTA311_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		3 / 3 TYR A 466
ARG A 365
HIS A 368
 None
 1.07A 4fubA-6etzA:
undetectable		 4fubA-6etzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KRH_B_SAMB900_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE
2)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		4 / 4 ILE A 312
SER A 311
ASP A 459
ASP A 457
 None
 1.32A 4krhB-6etzA:
undetectable		 4krhB-6etzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_C_SAMC405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		4 / 7 HIS A 372
PRO A 373
PHE A 215
ASP A 150
 None
 1.24A 4ndnC-6etzA:
undetectable		 4ndnC-6etzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODJ_A_SAMA500_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		4 / 7 HIS A 372
PRO A 373
PHE A 215
ASP A 150
 None
 1.24A 4odjA-6etzA:
undetectable		 4odjA-6etzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q0B_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		4 / 8 LEU A 147
VAL A 192
VAL A 133
LEU A 165
 None
 1.17A 4q0bA-6etzA:
undetectable		 4q0bA-6etzA:
9.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UIN_H_QI9H1226_0
(FAB 314.3)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		5 / 12 THR A 874
GLY A 932
ARG A 933
GLY A 750
PRO A 752
 None
 1.47A 4uinH-6etzA:
6.3
4uinL-6etzA:
undetectable		 4uinH-6etzA:
undetectable
4uinL-6etzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UIN_H_QI9H1226_0
(FAB 314.3)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		5 / 12 THR A 969
GLY A 931
ARG A 933
GLY A 750
PRO A 752
 None
 1.31A 4uinH-6etzA:
6.3
4uinL-6etzA:
undetectable		 4uinH-6etzA:
undetectable
4uinL-6etzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A1I_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		4 / 7 HIS A 372
PRO A 373
PHE A 215
ASP A 150
 None
 1.26A 5a1iA-6etzA:
undetectable		 5a1iA-6etzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXD_A_RBVA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		3 / 3 THR A 765
HIS A 975
LEU A 995
 None
 0.73A 5axdA-6etzA:
undetectable		 5axdA-6etzA:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CP3_A_YTZA301_1
(LIGHT CHAIN OF
ANTIGEN-BINDING
FRAGMENT OF
MONOCLONAL ANTIBODY
OF 4C7
HEAVY CHAIN OF
ANTIGEN-BINDING
FRAGMENT OF
MONOCLONAL ANTIBODY
OF 4C7)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		5 / 11 LEU A 416
ARG A 419
TRP A 412
ASN A 405
ALA A 442
 None
 1.49A 5cp3A-6etzA:
3.0
5cp3H-6etzA:
5.2		 5cp3A-6etzA:
16.82
5cp3H-6etzA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E9Q_C_SAMC4000_0
(GENOME POLYPROTEIN)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		6 / 12 GLY A 706
GLY A 894
THR A 685
GLU A 702
VAL A 611
ILE A 609
 None
 1.44A 5e9qC-6etzA:
undetectable		 5e9qC-6etzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EHG_A_SAMA301_0
(RNA-DIRECTED RNA
POLYMERASE NS5)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		6 / 12 GLY A 706
GLY A 894
THR A 685
GLU A 702
VAL A 611
ILE A 609
 None
 1.50A 5ehgA-6etzA:
undetectable		 5ehgA-6etzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EIF_C_SAMC4000_0
(GENOME POLYPROTEIN)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		6 / 12 GLY A 706
GLY A 894
THR A 685
GLU A 702
VAL A 611
ILE A 609
 None
 1.45A 5eifC-6etzA:
undetectable		 5eifC-6etzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESH_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		4 / 5 TRP A 696
LEU A 291
PRO A 289
LEU A 376
 None
 1.19A 5eshA-6etzA:
undetectable		 5eshA-6etzA:
9.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HES_A_032A401_2
(MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE KINASE MLT)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		4 / 6 LYS A 428
SER A  53
VAL A 303
ASP A 230
 None
 1.18A 5hesA-6etzA:
undetectable		 5hesA-6etzA:
16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNX_B_TA1B902_1
(TUBULIN BETA-2B
CHAIN)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		5 / 12 LEU A 756
LEU A 842
THR A 832
ARG A 815
ARG A 740
 None
None
None
MLI  A1106 (-3.6A)
None
 1.24A 5hnxB-6etzA:
undetectable		 5hnxB-6etzA:
11.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IAO_A_URFA301_1
(BIFUNCTIONAL PROTEIN
PYRR)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		4 / 4 ARG A 172
ASP A 391
HIS A 334
ARG A 342
 None
 1.36A 5iaoA-6etzA:
0.0		 5iaoA-6etzA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_B_CELB602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		4 / 6 VAL A 387
VAL A 477
SER A 479
ILE A 491
 None
 1.03A 5jw1B-6etzA:
undetectable		 5jw1B-6etzA:
8.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5B_A_SAMA1001_0
(NS5
METHYLTRANSFERASE)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		6 / 12 GLY A 706
GLY A 894
THR A 685
GLU A 702
VAL A 611
ILE A 609
 None
 1.40A 5m5bA-6etzA:
undetectable		 5m5bA-6etzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MRA_B_DM2B204_1
(SORCIN)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		4 / 6 TYR A 108
PHE A 581
ASP A 571
GLY A 570
 None
 1.15A 5mraA-6etzA:
undetectable
5mraB-6etzA:
undetectable		 5mraA-6etzA:
19.16
5mraB-6etzA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OS7_A_ACTA403_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		4 / 4 ARG A 342
TYR A 369
HIS A 334
HIS A 553
 None
 1.16A 5os7A-6etzA:
0.0		 5os7A-6etzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TRQ_B_ACTB307_0
(WELO5)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		3 / 3 GLU A 335
HIS A 336
VAL A 344
 None
 0.82A 5trqB-6etzA:
undetectable		 5trqB-6etzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_D_ERMD1201_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		5 / 12 SER A 311
PHE A 309
VAL A 261
LEU A 266
VAL A 281
 None
 1.29A 5tudD-6etzA:
undetectable		 5tudD-6etzA:
10.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_A_RITA602_1
(CYTOCHROME P450 3A5)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		5 / 12 LEU A 756
PHE A1002
ILE A 748
ALA A 926
GLY A 939
 None
 1.13A 5veuA-6etzA:
undetectable		 5veuA-6etzA:
9.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_A_C2FA3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		5 / 12 ARG A 594
GLY A 523
LEU A 977
GLY A 918
ARG A 960
 None
 1.20A 5vooA-6etzA:
undetectable		 5vooA-6etzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_C_C2FC702_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		5 / 12 ARG A 594
GLY A 523
LEU A 977
GLY A 918
ARG A 960
 None
 1.17A 5vooC-6etzA:
5.1		 5vooC-6etzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIM_C_SORC397_0
(D-XYLOSE ISOMERASE)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		5 / 12 TRP A 548
HIS A 334
GLU A 393
GLU A 441
HIS A 395
 None
 1.42A 5ximC-6etzA:
4.8		 5ximC-6etzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YJ1_G_6ELG501_0
(PROTEIN CEREBLON)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		4 / 8 HIS A 520
PHE A 600
HIS A 553
TRP A 548
 None
 1.10A 5yj1G-6etzA:
undetectable
5yj1Y-6etzA:
undetectable		 5yj1G-6etzA:
undetectable
5yj1Y-6etzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YJ1_T_6ELT501_0
(PROTEIN CEREBLON)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		4 / 8 HIS A 553
TRP A 548
HIS A 520
PHE A 600
 None
 1.06A 5yj1k-6etzA:
undetectable
5yj1t-6etzA:
undetectable		 5yj1k-6etzA:
undetectable
5yj1t-6etzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_A_SAMA401_1
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		3 / 3 ASP A 830
ARG A 815
ASP A 849
 None
MLI  A1106 (-3.6A)
None
 0.88A 5zvgA-6etzA:
undetectable		 5zvgA-6etzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXN_B_SAMB901_0
(DIPHTHAMIDE
BIOSYNTHESIS ENZYME
DPH2)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		5 / 12 LEU A 515
GLY A 545
VAL A 321
ILE A 326
ASP A 625
 None
 1.13A 6bxnB-6etzA:
undetectable		 6bxnB-6etzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBN_B_SAMB401_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		4 / 8 HIS A 372
PRO A 373
PHE A 215
ASP A 150
 None
 1.22A 6fbnB-6etzA:
undetectable		 6fbnB-6etzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_ACTA811_0
(GEPHYRIN)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		3 / 3 LEU A 963
LEU A 954
ARG A 947
 None
 0.58A 6fgcA-6etzA:
undetectable		 6fgcA-6etzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA810_0
(GEPHYRIN)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		3 / 3 LEU A 963
LEU A 954
ARG A 947
 None
 0.59A 6fgdA-6etzA:
undetectable		 6fgdA-6etzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G6R_A_SAMA406_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		4 / 7 HIS A 372
PRO A 373
PHE A 215
ASP A 150
 None
 1.26A 6g6rA-6etzA:
undetectable		 6g6rA-6etzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GMD_B_ACTB403_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		4 / 4 ARG A 342
TYR A 369
HIS A 334
HIS A 553
 None
 1.16A 6gmdB-6etzA:
0.0		 6gmdB-6etzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNF_C_QPSC602_2
(-)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		5 / 12 VAL A 248
HIS A 430
ARG A  48
GLU A 176
GLU A 301
 None
 1.13A 6gnfC-6etzA:
undetectable		 6gnfC-6etzA:
9.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_B_QPSB601_2
(-)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		5 / 12 GLY A 545
GLY A 544
LEU A 328
GLY A 439
PRO A 512
 None
 1.00A 6gngB-6etzA:
undetectable		 6gngB-6etzA:
8.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_F_AM2F301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 6etz BETA-GALACTOSIDASE
(Arthrobacter
sp.
32cB) 		4 / 7 TRP A 548
HIS A 368
GLU A 393
GLU A 398
 None
 1.38A 6mn4F-6etzA:
undetectable		 6mn4F-6etzA:
undetectable