SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6eu0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2FK8_A_SAMA302_0 (METHOXY MYCOLIC ACID SYNTHASE 4)	6eu0	TRANSCRIPTION FACTOR IIIB 70 KDA SUBUNIT (Saccharomyces cerevisiae)	5 / 12	ILE Z 228 GLY Z 225 GLY Z 222 LEU Z 259 HIS Z 241	None	0.98A	2fk8A-6eu0Z: undetectable	2fk8A-6eu0Z: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LP9_D_SPMD230_1 (LS-24)	6eu0	TRANSCRIPTION FACTOR TFIIIB COMPONENT B'' (Saccharomyces cerevisiae)	3 / 3	GLU V 337 GLU V 399 ASN V 400	None	0.86A	3lp9B-6eu0V: undetectable 3lp9D-6eu0V: undetectable	3lp9B-6eu0V: 14.54 3lp9D-6eu0V: 14.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5G5G_A_ACTA1231_0 (PUTATIVE XANTHINE DEHYDROGENASE YAGR MOLYBDENUM-BINDING SU SUBUNIT PUTATIVE XANTHINE DEHYDROGENASE YAGT IRON-SULFUR-BINDING SUBUNIT)	6eu0	TRANSCRIPTION FACTOR IIIB 70 KDA SUBUNIT (Saccharomyces cerevisiae)	3 / 3	ARG Z 84 THR Z 101 ASP Z 102	None	0.97A	5g5gA-6eu0Z: undetectable 5g5gB-6eu0Z: undetectable	5g5gA-6eu0Z: undetectable 5g5gB-6eu0Z: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DJZ_A_GMJA301_1 (SIGMA NON-OPIOID INTRACELLULAR RECEPTOR 1)	6eu0	TRANSCRIPTION FACTOR IIIB 70 KDA SUBUNIT (Saccharomyces cerevisiae)	4 / 6	SER Z 271 ASP Z 279 GLU Z 281 THR Z 265	None	1.39A	6djzA-6eu0Z: undetectable	6djzA-6eu0Z: undetectable

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2FK8_A_SAMA302_0","METHOXY MYCOLIC ACID SYNTHASE 4","6eu0","TRANSCRIPTION FACTOR IIIB 70 KDA SUBUNIT","Saccharomyces cerevisiae",5,"ILE Z 228;GLY Z 225;GLY Z 222;LEU Z 259;HIS Z 241","None","0.98A","2fk8A-6eu0Z:undetectable","2fk8A-6eu0Z:undetectable"],["3LP9_D_SPMD230_1","LS-24;LS-24","6eu0","TRANSCRIPTION FACTOR TFIIIB COMPONENT B''","Saccharomyces cerevisiae",3,"GLU V 337;GLU V 399;ASN V 400","None","0.86A","3lp9B-6eu0V:undetectable;3lp9D-6eu0V:undetectable","3lp9B-6eu0V:14.54;3lp9D-6eu0V:14.54"],["5G5G_A_ACTA1231_0","PUTATIVE XANTHINE DEHYDROGENASE YAGR MOLYBDENUM-BINDING SU SUBUNIT;PUTATIVE XANTHINE DEHYDROGENASE YAGT IRON-SULFUR-BINDING SUBUNIT","6eu0","TRANSCRIPTION FACTOR IIIB 70 KDA SUBUNIT","Saccharomyces cerevisiae",3,"ARG Z  84;THR Z 101;ASP Z 102","None","0.97A","5g5gA-6eu0Z:undetectable;5g5gB-6eu0Z:undetectable","5g5gA-6eu0Z:undetectable;5g5gB-6eu0Z:undetectable"],["6DJZ_A_GMJA301_1","SIGMA NON-OPIOID INTRACELLULAR RECEPTOR 1","6eu0","TRANSCRIPTION FACTOR IIIB 70 KDA SUBUNIT","Saccharomyces cerevisiae",4,"SER Z 271;ASP Z 279;GLU Z 281;THR Z 265","None","1.39A","6djzA-6eu0Z:undetectable","6djzA-6eu0Z:undetectable"]]