SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6eua'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VID_A_SAMA301_1
(CATECHOL
O-METHYLTRANSFERASE)		 6eua ANGIOPOIETIN-RELATED
PROTEIN 3
(Homo
sapiens) 		4 / 5 SER A 280
GLU A 346
TYR A 344
SER A 348
 None
 1.41A 1vidA-6euaA:
undetectable		 1vidA-6euaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CL5_B_SAMB1217_1
(CATECHOL
O-METHYLTRANSFERASE)		 6eua ANGIOPOIETIN-RELATED
PROTEIN 3
(Homo
sapiens) 		4 / 6 SER A 280
GLU A 346
TYR A 344
SER A 348
 None
 1.42A 2cl5B-6euaA:
undetectable		 2cl5B-6euaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA507_0
(CHORISMATE SYNTHASE)		 6eua ANGIOPOIETIN-RELATED
PROTEIN 3
(Homo
sapiens) 		3 / 3 LEU A 432
ASN A 414
ARG A 288
 None
 0.94A 2qhfA-6euaA:
undetectable		 2qhfA-6euaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_C_DVAC8_0
(GRAMICIDIN A)		 6eua ANGIOPOIETIN-RELATED
PROTEIN 3
(Homo
sapiens) 		3 / 3 VAL A 380
TRP A 402
TRP A 404
 None
 1.38A 2xdcC-6euaA:
undetectable
2xdcD-6euaA:
undetectable		 2xdcC-6euaA:
undetectable
2xdcD-6euaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VT7_A_VDXA500_2
(VITAMIN D3 RECEPTOR)		 6eua ANGIOPOIETIN-RELATED
PROTEIN 3
(Homo
sapiens) 		4 / 4 LEU A 450
ILE A 262
TYR A 329
TYR A 273
 None
 1.26A 3vt7A-6euaA:
undetectable		 3vt7A-6euaA:
13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7C_A_ACTA504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 6eua ANGIOPOIETIN-RELATED
PROTEIN 3
(Homo
sapiens) 		3 / 3 ARG A 430
TRP A 338
GLY A 431
 None
 0.84A 4e7cA-6euaA:
undetectable		 4e7cA-6euaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRQ_C_AVLC203_1
(MACROPHAGE MIGRATION
INHIBITORY FACTOR)		 6eua ANGIOPOIETIN-RELATED
PROTEIN 3
(Homo
sapiens) 		5 / 7 PHE A 306
TYR A 302
GLN A 286
TRP A 314
PHE A 381
 None
 1.46A 4grqA-6euaA:
undetectable
4grqC-6euaA:
undetectable		 4grqA-6euaA:
19.13
4grqC-6euaA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_A_ADNA401_1
(ADENOSINE KINASE)		 6eua ANGIOPOIETIN-RELATED
PROTEIN 3
(Homo
sapiens) 		5 / 12 ASN A 301
ASN A 296
PHE A 306
ASN A 412
GLY A 415
 None
 1.19A 4n09A-6euaA:
undetectable		 4n09A-6euaA:
12.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBE_A_2FAA401_1
(ADENOSINE KINASE)		 6eua ANGIOPOIETIN-RELATED
PROTEIN 3
(Homo
sapiens) 		5 / 12 SER A 399
GLY A 401
GLY A 400
ASN A 412
PHE A 295
 None
 1.30A 4ubeA-6euaA:
undetectable		 4ubeA-6euaA:
12.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHR_A_SAMA303_1
(CATECHOL
O-METHYLTRANSFERASE)		 6eua ANGIOPOIETIN-RELATED
PROTEIN 3
(Homo
sapiens) 		4 / 5 SER A 280
GLU A 346
TYR A 344
SER A 348
 None
 1.41A 5fhrA-6euaA:
undetectable		 5fhrA-6euaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_G_CHDG104_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 6eua ANGIOPOIETIN-RELATED
PROTEIN 3
(Homo
sapiens) 		5 / 11 GLY A 415
GLY A 291
GLN A 293
GLU A 312
THR A 447
 None
 1.28A 5x19G-6euaA:
undetectable
5x19N-6euaA:
undetectable
5x19O-6euaA:
undetectable		 5x19G-6euaA:
undetectable
5x19N-6euaA:
undetectable
5x19O-6euaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A93_A_8NUA3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 6eua ANGIOPOIETIN-RELATED
PROTEIN 3
(Homo
sapiens) 		5 / 12 LEU A 362
PHE A 306
TRP A 314
PHE A 381
LEU A 351
 None
 1.32A 6a93A-6euaA:
undetectable		 6a93A-6euaA:
undetectable