SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6eub'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_C_THAC3_1
(LIVER
CARBOXYLESTERASE I)		 6eub ANGIOPOIETIN-RELATED
PROTEIN 4
(Homo
sapiens) 		5 / 12 VAL A 275
LEU A 287
LEU A 390
LEU A 277
HIS A 356
 None
None
None
None
1PE  A 501 ( 4.3A)
 1.00A 1mx1C-6eubA:
undetectable		 1mx1C-6eubA:
7.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_F_THAF6_1
(LIVER
CARBOXYLESTERASE I)		 6eub ANGIOPOIETIN-RELATED
PROTEIN 4
(Homo
sapiens) 		5 / 12 VAL A 275
LEU A 287
LEU A 390
LEU A 277
HIS A 356
 None
None
None
None
1PE  A 501 ( 4.3A)
 0.95A 1mx1F-6eubA:
undetectable		 1mx1F-6eubA:
7.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1435_1
(CHITINASE)		 6eub ANGIOPOIETIN-RELATED
PROTEIN 4
(Homo
sapiens) 		3 / 3 TRP A 241
GLU A 296
TYR A 300
 None
 1.11A 2a3aA-6eubA:
undetectable		 2a3aA-6eubA:
10.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_2
(PROTEASE RETROPEPSIN)		 6eub ANGIOPOIETIN-RELATED
PROTEIN 4
(Homo
sapiens) 		3 / 3 ARG A 229
THR A 225
VAL A 226
 None
 0.86A 2q64A-6eubA:
undetectable		 2q64A-6eubA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA503_0
(CHORISMATE SYNTHASE)		 6eub ANGIOPOIETIN-RELATED
PROTEIN 4
(Homo
sapiens) 		4 / 5 GLN A 276
THR A 394
ALA A 392
ARG A 278
 None
 1.46A 2qhfA-6eubA:
undetectable		 2qhfA-6eubA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WA2_B_SAMB1267_1
(NON-STRUCTURAL
PROTEIN 5)		 6eub ANGIOPOIETIN-RELATED
PROTEIN 4
(Homo
sapiens) 		3 / 3 SER A 357
HIS A 333
ASP A 330
 1PE  A 501 ( 4.0A)
None
None
 0.60A 2wa2B-6eubA:
undetectable		 2wa2B-6eubA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCN_A_CHDA3_0
(FERROCHELATASE,
MITOCHONDRIAL)		 6eub ANGIOPOIETIN-RELATED
PROTEIN 4
(Homo
sapiens) 		4 / 7 LEU A 257
PRO A 399
SER A 271
GLY A 223
 None
 1.11A 3hcnA-6eubA:
undetectable		 3hcnA-6eubA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_P_TFPP201_1
(PROTEIN S100-A4)		 6eub ANGIOPOIETIN-RELATED
PROTEIN 4
(Homo
sapiens) 		4 / 7 PHE A 237
GLY A 361
GLY A 233
PHE A 326
 None
 0.82A 3ko0M-6eubA:
undetectable
3ko0P-6eubA:
undetectable		 3ko0M-6eubA:
18.87
3ko0P-6eubA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X3M_A_ADNA301_1
(RNA 2'-O RIBOSE
METHYLTRANSFERASE)		 6eub ANGIOPOIETIN-RELATED
PROTEIN 4
(Homo
sapiens) 		5 / 9 LEU A 257
GLY A 258
ILE A 204
SER A 209
VAL A 262
 None
 1.33A 4x3mA-6eubA:
undetectable		 4x3mA-6eubA:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XO7_B_ASDB402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 6eub ANGIOPOIETIN-RELATED
PROTEIN 4
(Homo
sapiens) 		4 / 7 VAL A 275
ILE A 227
TRP A 350
LEU A 304
 None
 1.22A 4xo7B-6eubA:
undetectable		 4xo7B-6eubA:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4H_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 6eub ANGIOPOIETIN-RELATED
PROTEIN 4
(Homo
sapiens) 		4 / 5 ARG A 269
GLN A 207
ILE A 265
ASP A 187
 None
 1.30A 4z4hA-6eubA:
undetectable		 4z4hA-6eubA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4H_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 6eub ANGIOPOIETIN-RELATED
PROTEIN 4
(Homo
sapiens) 		4 / 5 ARG A 269
GLN A 207
PRO A 206
ILE A 265
 None
 1.43A 4z4hA-6eubA:
undetectable		 4z4hA-6eubA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KI6_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 6eub ANGIOPOIETIN-RELATED
PROTEIN 4
(Homo
sapiens) 		4 / 5 ARG A 269
GLN A 207
PRO A 206
ILE A 265
 None
 1.45A 5ki6A-6eubA:
undetectable		 5ki6A-6eubA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZY_A_CE3A1103_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 6eub ANGIOPOIETIN-RELATED
PROTEIN 4
(Homo
sapiens) 		4 / 8 TYR A 244
ASP A 332
GLY A 361
ARG A 230
 None
 0.95A 5nzyA-6eubA:
undetectable		 5nzyA-6eubA:
12.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_D_ADND502_1
(ADENOSYLHOMOCYSTEINA
SE)		 6eub ANGIOPOIETIN-RELATED
PROTEIN 4
(Homo
sapiens) 		3 / 3 LEU A 273
ASN A 360
LEU A 259
 None
 0.75A 6exiD-6eubA:
undetectable		 6exiD-6eubA:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_C_ADNC501_2
(-)		 6eub ANGIOPOIETIN-RELATED
PROTEIN 4
(Homo
sapiens) 		4 / 5 THR A 393
THR A 382
HIS A 356
GLY A 377
 None
None
1PE  A 501 ( 4.3A)
None
 1.21A 6gbnC-6eubA:
undetectable		 6gbnC-6eubA:
10.86