SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6euv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBY_B_9CRB1500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 6euv POLYMERASE BASIC
PROTEIN 2
(Influenza
A
virus) 		5 / 12 ILE A 310
CYH A 311
ALA A 313
ALA A 314
VAL A 518
 None
 0.97A 1fbyB-6euvA:
undetectable		 1fbyB-6euvA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_A_CHDA1501_0
(FERROCHELATASE)		 6euv POLYMERASE BASIC
PROTEIN 2
(Influenza
A
virus) 		5 / 12 LEU A 298
MET A 315
ILE A 289
LEU A 513
VAL A 504
 None
 1.10A 1hrkA-6euvA:
undetectable		 1hrkA-6euvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XIU_A_9CRA201_1
(RXR-LIKE PROTEIN)		 6euv POLYMERASE BASIC
PROTEIN 2
(Influenza
A
virus) 		5 / 12 ILE A 310
CYH A 311
ALA A 313
ALA A 314
VAL A 518
 None
 1.02A 1xiuA-6euvA:
undetectable		 1xiuA-6euvA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_B_CHDB1605_0
(FERROCHELATASE)		 6euv POLYMERASE BASIC
PROTEIN 2
(Influenza
A
virus) 		5 / 12 LEU A 298
MET A 315
ILE A 289
LEU A 513
VAL A 504
 None
 1.15A 2hrcB-6euvA:
undetectable		 2hrcB-6euvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_A_CHDA501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 6euv POLYMERASE BASIC
PROTEIN 2
(Influenza
A
virus) 		5 / 12 LEU A 298
MET A 315
ILE A 289
LEU A 513
VAL A 504
 None
 1.15A 2po5A-6euvA:
undetectable		 2po5A-6euvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO7_B_CHDB501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 6euv POLYMERASE BASIC
PROTEIN 2
(Influenza
A
virus) 		5 / 12 LEU A 298
MET A 315
ILE A 289
LEU A 513
VAL A 504
 None
 1.24A 2po7B-6euvA:
undetectable		 2po7B-6euvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ENT_C_MIYC901_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT
ACRB,MULTIDRUG
EFFLUX PUMP SUBUNIT
ACRB)		 6euv POLYMERASE BASIC
PROTEIN 2
(Influenza
A
virus) 		5 / 9 GLN A 383
SER A 405
GLU A 407
ILE A 398
ALA A 397
 None
 1.20A 5entC-6euvA:
undetectable		 5entC-6euvA:
9.36