SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6exp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_A_FFOA1002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 6exp SIRV3 ACRID1 (GP02)
ANTI-CRISPR PROTEIN
(Sulfolobus
islandicus
rudivirus
3) 		4 / 5 GLU A  58
TYR A  76
PHE A  60
PRO A  46
 None
 1.10A 1dfoB-6expA:
undetectable		 1dfoB-6expA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_B_FFOB2002_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 6exp SIRV3 ACRID1 (GP02)
ANTI-CRISPR PROTEIN
(Sulfolobus
islandicus
rudivirus
3) 		4 / 5 GLU A  58
TYR A  76
PHE A  60
PRO A  46
 None
 1.10A 1dfoA-6expA:
undetectable		 1dfoA-6expA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_C_FFOC3002_2
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 6exp SIRV3 ACRID1 (GP02)
ANTI-CRISPR PROTEIN
(Sulfolobus
islandicus
rudivirus
3) 		4 / 5 GLU A  58
TYR A  76
PHE A  60
PRO A  46
 None
 1.10A 1dfoD-6expA:
undetectable		 1dfoD-6expA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_D_FFOD4002_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 6exp SIRV3 ACRID1 (GP02)
ANTI-CRISPR PROTEIN
(Sulfolobus
islandicus
rudivirus
3) 		4 / 5 GLU A  58
TYR A  76
PHE A  60
PRO A  46
 None
 1.10A 1dfoC-6expA:
undetectable		 1dfoC-6expA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VMY_A_FFOA505_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 6exp SIRV3 ACRID1 (GP02)
ANTI-CRISPR PROTEIN
(Sulfolobus
islandicus
rudivirus
3) 		4 / 6 GLU A  58
TYR A  76
PHE A  60
PRO A  46
 None
 1.23A 2vmyA-6expA:
undetectable		 2vmyA-6expA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZC_A_ACTA401_0
(PROTON-GATED ION
CHANNEL)		 6exp SIRV3 ACRID1 (GP02)
ANTI-CRISPR PROTEIN
(Sulfolobus
islandicus
rudivirus
3) 		4 / 6 ILE A  83
PHE A  37
ILE A  56
GLU A  58
 None
 1.24A 4zzcA-6expA:
undetectable
4zzcB-6expA:
undetectable		 4zzcA-6expA:
undetectable
4zzcB-6expA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZC_B_ACTB401_0
(PROTON-GATED ION
CHANNEL)		 6exp SIRV3 ACRID1 (GP02)
ANTI-CRISPR PROTEIN
(Sulfolobus
islandicus
rudivirus
3) 		4 / 6 ILE A  83
PHE A  37
ILE A  56
GLU A  58
 None
 1.23A 4zzcB-6expA:
undetectable
4zzcC-6expA:
undetectable		 4zzcB-6expA:
undetectable
4zzcC-6expA:
undetectable