SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6exv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CD2_A_FOLA307_1
(DIHYDROFOLATE
REDUCTASE)		 6exv DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB2
(Sus
scrofa) 		3 / 3 GLU B 669
ILE B 604
ARG B 392
 None
 0.81A 1cd2A-6exvB:
undetectable		 1cd2A-6exvB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3003_1
(SERUM ALBUMIN)		 6exv DNA-DIRECTED RNA
POLYMERASES I, II,
AND III SUBUNIT
RPABC1
(Sus
scrofa) 		3 / 4 LYS E 115
ALA E 114
MET E 110
 None
 0.96A 1hk3A-6exvE:
undetectable		 1hk3A-6exvE:
8.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 6exv DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB2
(Sus
scrofa) 		5 / 12 LEU B 318
ALA B 339
LEU B 343
MET B 347
VAL B 267
 None
 1.14A 1sa1C-6exvB:
undetectable
1sa1D-6exvB:
undetectable		 1sa1C-6exvB:
11.40
1sa1D-6exvB:
9.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SV5_A_65BA600_0
(REVERSE
TRANSCRIPTASE)		 6exv DNA-DIRECTED RNA
POLYMERASES I, II,
AND III SUBUNIT
RPABC1
(Sus
scrofa) 		5 / 10 LEU E  20
VAL E  60
VAL E  28
TYR E  26
LEU E 103
 None
 1.18A 1sv5A-6exvE:
undetectable		 1sv5A-6exvE:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VIF_A_FOLA1_0
(DIHYDROFOLATE
REDUCTASE)		 6exv DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB2
(Sus
scrofa) 		3 / 3 GLN B  90
ILE B  91
TYR B  92
 None
 0.71A 1vifA-6exvB:
undetectable		 1vifA-6exvB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XIU_B_9CRB202_1
(RXR-LIKE PROTEIN)		 6exv DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB2
(Sus
scrofa) 		5 / 12 ILE B 271
ALA B 275
GLN B 314
LEU B 318
LEU B 260
 None
 0.97A 1xiuB-6exvB:
undetectable		 1xiuB-6exvB:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVD_B_SAMB601_1
(CATECHOL-O-METHYLTRA
NSFERASE)		 6exv DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB2
(Sus
scrofa) 		3 / 3 SER B 893
GLU B 830
ASP B 850
 None
 0.89A 2avdB-6exvB:
undetectable		 2avdB-6exvB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GL0_C_ADNC903_1
(CONSERVED
HYPOTHETICAL PROTEIN)		 6exv DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB2
DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB3
(Sus
scrofa) 		5 / 12 ASN C  55
TYR B 753
HIS C  60
PHE C  63
SER C  57
 None
 1.10A 2gl0A-6exvC:
undetectable
2gl0C-6exvC:
undetectable		 2gl0A-6exvC:
20.61
2gl0C-6exvC:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GL0_D_ADND904_1
(CONSERVED
HYPOTHETICAL PROTEIN)		 6exv DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB2
(Sus
scrofa) 		5 / 12 HIS B 716
PHE B 713
ASN B 717
ILE B 982
VAL B 759
 None
 1.49A 2gl0D-6exvB:
undetectable
2gl0E-6exvB:
undetectable		 2gl0D-6exvB:
21.38
2gl0E-6exvB:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GL0_D_ADND904_1
(CONSERVED
HYPOTHETICAL PROTEIN)		 6exv DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB2
DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB3
(Sus
scrofa) 		5 / 12 HIS C  60
PHE C  63
SER C  57
ASN C  55
TYR B 753
 None
 1.10A 2gl0D-6exvC:
undetectable
2gl0E-6exvC:
undetectable		 2gl0D-6exvC:
20.61
2gl0E-6exvC:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I30_A_SALA1100_1
(SERUM ALBUMIN)		 6exv DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB2
DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB3
(Sus
scrofa) 		4 / 6 PHE B 956
TYR C 186
ARG B1035
GLY B1034
 None
 1.47A 2i30A-6exvB:
undetectable		 2i30A-6exvB:
8.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEB_A_HSMA145_1
(D7R4 PROTEIN)		 6exv DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB2
(Sus
scrofa) 		4 / 7 ILE B 597
ARG B 591
ASP B 666
GLU B 669
 None
 1.09A 2qebA-6exvB:
undetectable		 2qebA-6exvB:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEB_B_HSMB145_1
(D7R4 PROTEIN)		 6exv DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB2
(Sus
scrofa) 		4 / 7 ILE B 597
ARG B 591
ASP B 666
GLU B 669
 None
 1.16A 2qebB-6exvB:
undetectable		 2qebB-6exvB:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UZ2_A_ACTA1123_0
(XENAVIDIN)		 6exv DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB3
(Sus
scrofa) 		4 / 7 ASN C  55
LEU C 159
SER C  57
VAL C 151
 None
 1.09A 2uz2A-6exvC:
undetectable		 2uz2A-6exvC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_A_ACRA5044_2
(GLUCOSYLTRANSFERASE-
SI)		 6exv DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB2
(Sus
scrofa) 		3 / 3 LEU B  39
TRP B 653
TYR B 766
 None
 0.98A 3aicA-6exvB:
undetectable		 3aicA-6exvB:
6.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_B_ACRB5044_2
(GLUCOSYLTRANSFERASE-
SI)		 6exv DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB2
(Sus
scrofa) 		3 / 3 LEU B  39
TRP B 653
TYR B 766
 None
 1.01A 3aicB-6exvB:
undetectable		 3aicB-6exvB:
6.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_E_ACRE5044_2
(GLUCOSYLTRANSFERASE-
SI)		 6exv DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB2
(Sus
scrofa) 		3 / 3 LEU B  39
TRP B 653
TYR B 766
 None
 0.99A 3aicE-6exvB:
undetectable		 3aicE-6exvB:
6.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_F_ACRF5044_2
(GLUCOSYLTRANSFERASE-
SI)		 6exv DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB2
(Sus
scrofa) 		3 / 3 LEU B  39
TRP B 653
TYR B 766
 None
 0.96A 3aicF-6exvB:
undetectable		 3aicF-6exvB:
6.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_G_ACRG5044_2
(GLUCOSYLTRANSFERASE-
SI)		 6exv DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB2
(Sus
scrofa) 		3 / 3 LEU B  39
TRP B 653
TYR B 766
 None
 0.97A 3aicG-6exvB:
undetectable		 3aicG-6exvB:
6.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_H_ACRH5044_2
(GLUCOSYLTRANSFERASE-
SI)		 6exv DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB2
(Sus
scrofa) 		3 / 3 LEU B  39
TRP B 653
TYR B 766
 None
 0.99A 3aicH-6exvB:
undetectable		 3aicH-6exvB:
6.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CKZ_A_ZMRA469_2
(NEURAMINIDASE)		 6exv DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB2
(Sus
scrofa) 		4 / 6 ASP B 394
ARG B 463
TRP B 453
SER B  46
 None
 1.29A 3ckzA-6exvB:
undetectable		 3ckzA-6exvB:
11.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CL9_A_MTXA602_2
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE (DHFR-TS))		 6exv DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB2
(Sus
scrofa) 		4 / 4 VAL B 735
ARG B 770
ILE B 710
THR B 738
 None
 1.37A 3cl9A-6exvB:
undetectable		 3cl9A-6exvB:
10.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHX_B_PXLB313_1
(PYRIDOXAL KINASE)		 6exv DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB2
(Sus
scrofa) 		4 / 8 VAL B 193
VAL B  40
HIS B 481
THR B 478
 None
 1.06A 3fhxB-6exvB:
undetectable		 3fhxB-6exvB:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PO7_A_ZONA601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 6exv DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB2
(Sus
scrofa) 		4 / 8 TYR B1047
CYH B 707
GLN B1049
PHE B 769
 None
 1.31A 3po7A-6exvB:
undetectable		 3po7A-6exvB:
9.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PRS_A_RITA1001_2
(ENDOTHIAPEPSIN)		 6exv DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB2
(Sus
scrofa) 		5 / 12 ASP B1004
ASP B 715
GLY B 997
ASP B 998
ILE B1011
 None
 1.12A 3prsA-6exvB:
undetectable		 3prsA-6exvB:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEL_D_QELD2_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE [NMDA]
RECEPTOR SUBUNIT
EPSILON-2)		 6exv DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB2
(Sus
scrofa) 		4 / 5 TYR B 736
THR B 474
PHE B 475
LEU B 470
 None
 1.06A 3qelC-6exvB:
2.1		 3qelC-6exvB:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Z_C_9PLC501_1
(CYTOCHROME P450 2E1)		 6exv DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB3
(Sus
scrofa) 		4 / 5 PHE C  38
ALA C  31
THR C  26
LEU C 249
 None
 1.09A 3t3zC-6exvC:
undetectable		 3t3zC-6exvC:
10.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_C_ACTC610_0
(GBAA_1210 PROTEIN)		 6exv DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB2
DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB3
(Sus
scrofa;
Sus
scrofa) 		3 / 3 ASN C 177
ALA C 174
ARG B 803
 None
 0.87A 3tj7C-6exvC:
undetectable
3tj7D-6exvC:
undetectable		 3tj7C-6exvC:
undetectable
3tj7D-6exvC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V35_A_NTIA317_1
(ALDOSE REDUCTASE)		 6exv DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB2
DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB3
(Sus
scrofa) 		4 / 8 VAL B 809
HIS C  60
PHE B 740
PRO B 754
 None
 0.88A 3v35A-6exvB:
undetectable		 3v35A-6exvB:
14.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V81_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 6exv DNA-DIRECTED RNA
POLYMERASES I, II,
AND III SUBUNIT
RPABC1
(Sus
scrofa) 		4 / 8 VAL E  60
VAL E  28
TYR E  26
LEU E 103
 None
 1.06A 3v81C-6exvE:
2.2		 3v81C-6exvE:
11.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_C_VIVC301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 6exv DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB3
(Sus
scrofa) 		5 / 12 ILE C 121
SER C  75
ALA C 165
PHE C 101
ILE C  71
 None
 1.19A 3w67C-6exvC:
undetectable		 3w67C-6exvC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_C_MIYC392_1
(TETX2 PROTEIN)		 6exv DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB2
(Sus
scrofa) 		5 / 12 ARG B1050
PHE B 935
VAL B 801
ILE B 928
ILE B 931
 None
 1.49A 4a99A-6exvB:
0.0
4a99C-6exvB:
1.7		 4a99A-6exvB:
13.10
4a99C-6exvB:
13.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_A_CHDA505_0
(FERROCHELATASE,
MITOCHONDRIAL)		 6exv DNA-DIRECTED RNA
POLYMERASES I, II,
AND III SUBUNIT
RPABC1
(Sus
scrofa) 		4 / 7 ILE E  13
ARG E  14
VAL E  60
MET E  72
 None
 1.43A 4f4dA-6exvE:
undetectable		 4f4dA-6exvE:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KRH_B_SAMB900_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE
2)		 6exv DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB2
(Sus
scrofa) 		4 / 4 ILE B 711
SER B 709
ASP B 715
ASP B1004
 None
 1.45A 4krhB-6exvB:
undetectable		 4krhB-6exvB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1A_A_AB1A101_2
(MDR769 HIV-1
PROTEASE)		 6exv DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB2
(Sus
scrofa) 		4 / 6 ARG B 938
GLY B1024
PRO B1045
THR B1046
 None
 0.95A 4l1aB-6exvB:
undetectable		 4l1aB-6exvB:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_D_SAMD601_1
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 6exv DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB2
(Sus
scrofa) 		3 / 3 ASN B 203
ASP B 617
ASP B 394
 None
 0.81A 4obwD-6exvB:
undetectable		 4obwD-6exvB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2O_B_CLQB1079_0
(SAPOSIN-B)		 6exv DNA-DIRECTED RNA
POLYMERASES I, II,
AND III SUBUNIT
RPABC1
(Sus
scrofa) 		3 / 3 MET E 151
GLU E 155
LEU E 159
 None
 0.79A 4v2oB-6exvE:
undetectable		 4v2oB-6exvE:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z91_F_4LEF401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 6exv DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB2
(Sus
scrofa) 		5 / 7 THR B 888
LEU B 873
THR B 836
THR B 870
THR B 872
 None
 1.41A 4z91F-6exvB:
1.4
4z91G-6exvB:
1.5
4z91H-6exvB:
1.4
4z91I-6exvB:
1.5
4z91J-6exvB:
1.5		 4z91F-6exvB:
11.49
4z91G-6exvB:
11.49
4z91H-6exvB:
11.49
4z91I-6exvB:
11.49
4z91J-6exvB:
11.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DQF_A_CZEA613_1
(SERUM ALBUMIN)		 6exv DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB3
(Sus
scrofa) 		5 / 9 ALA C 163
ASP C  48
GLY C  69
LEU C  68
LEU C 161
 None
 1.14A 5dqfA-6exvC:
undetectable		 5dqfA-6exvC:
9.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECN_A_LEUA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 6exv DNA-DIRECTED RNA
POLYMERASES I, II,
AND III SUBUNIT
RPABC1
(Sus
scrofa) 		4 / 7 ALA E 114
THR E 111
VAL E 106
LYS E  81
 None
 1.09A 5ecnA-6exvE:
undetectable		 5ecnA-6exvE:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB603_1
(PHIAB6 TAILSPIKE)		 6exv DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB2
(Sus
scrofa) 		3 / 3 VAL B 207
GLU B 611
GLU B 609
 None
 0.92A 5jsdB-6exvB:
undetectable
5jsdC-6exvB:
undetectable		 5jsdB-6exvB:
7.56
5jsdC-6exvB:
7.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U6N_A_SALA505_1
(UDP-GLYCOSYLTRANSFER
ASE 74F2)		 6exv DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB2
(Sus
scrofa) 		4 / 8 SER B 223
HIS B 350
PHE B 364
MET B 368
 None
 1.33A 5u6nA-6exvB:
undetectable		 5u6nA-6exvB:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8P_A_ACTA816_0
(UNCHARACTERIZED
PROTEIN)		 6exv DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB2
(Sus
scrofa) 		3 / 3 ARG B 924
ARG B 922
ASP B 905
 None
 0.98A 6d8pA-6exvB:
undetectable		 6d8pA-6exvB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKU_A_ZMRA901_1
(SIALIDASE)		 6exv DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB2
(Sus
scrofa) 		5 / 12 ARG B 157
ASN B 739
GLU B 191
ASP B 745
TYR B 184
 None
 1.18A 6ekuA-6exvB:
undetectable		 6ekuA-6exvB:
6.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F7L_B_ACTB505_0
(AMINE OXIDASE LKCE)		 6exv DNA-DIRECTED RNA
POLYMERASES I, II,
AND III SUBUNIT
RPABC1
(Sus
scrofa) 		3 / 3 HIS E  64
ASN E  65
LEU E  27
 None
 0.88A 6f7lB-6exvE:
undetectable		 6f7lB-6exvE:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA826_0
(GEPHYRIN)		 6exv DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB2
(Sus
scrofa) 		3 / 3 HIS B 695
ARG B 592
ILE B 627
 None
 0.80A 6fgdA-6exvB:
undetectable		 6fgdA-6exvB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6I0Y_A_TRPA3001_0
(23S RIBOSOMAL RNA
TRYPTOPHANASE OPERON
LEADER PEPTIDE)		 6exv DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB3
(Sus
scrofa) 		3 / 3 TRP C 176
ILE C  47
ASP C  48
 None
 0.70A 6i0y7-6exvC:
undetectable		 6i0y7-6exvC:
undetectable