SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6ey4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_A_NIOA221_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 6ey4 GLDM
(Flavobacterium
johnsoniae) 		4 / 6 SER A 270
THR A 301
PHE A 313
GLY A 273
 None
 1.07A 1icuA-6ey4A:
undetectable
1icuB-6ey4A:
undetectable		 1icuA-6ey4A:
19.10
1icuB-6ey4A:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_B_NIOB219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 6ey4 GLDM
(Flavobacterium
johnsoniae) 		4 / 6 PHE A 313
GLY A 273
SER A 270
THR A 301
 None
 1.05A 1icuA-6ey4A:
undetectable
1icuB-6ey4A:
undetectable		 1icuA-6ey4A:
19.10
1icuB-6ey4A:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_C_NIOC225_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 6ey4 GLDM
(Flavobacterium
johnsoniae) 		4 / 6 SER A 270
THR A 301
PHE A 313
GLY A 273
 None
 0.96A 1icuC-6ey4A:
undetectable
1icuD-6ey4A:
undetectable		 1icuC-6ey4A:
19.10
1icuD-6ey4A:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQB_C_BEZC522_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 6ey4 GLDM
(Flavobacterium
johnsoniae) 		4 / 6 SER A 270
THR A 301
PHE A 313
GLY A 273
 None
 1.08A 1kqbC-6ey4A:
undetectable
1kqbD-6ey4A:
undetectable		 1kqbC-6ey4A:
undetectable
1kqbD-6ey4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_A_DIFA1373_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 6ey4 GLDM
(Flavobacterium
johnsoniae) 		4 / 8 PHE A 172
VAL A 174
TYR A  92
PHE A 192
 None
 1.02A 2wekA-6ey4A:
undetectable		 2wekA-6ey4A:
12.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_B_DIFB1373_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 6ey4 GLDM
(Flavobacterium
johnsoniae) 		4 / 8 PHE A 172
VAL A 174
TYR A  92
PHE A 192
 None
 1.01A 2wekB-6ey4A:
undetectable		 2wekB-6ey4A:
12.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APW_A_DP0A190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 6ey4 GLDM
(Flavobacterium
johnsoniae) 		5 / 12 VAL A 218
ILE A 164
PHE A 172
SER A  86
TYR A 147
 None
 1.19A 3apwA-6ey4A:
undetectable		 3apwA-6ey4A:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APW_B_DP0B190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 6ey4 GLDM
(Flavobacterium
johnsoniae) 		5 / 12 VAL A 218
ILE A 164
PHE A 172
SER A  86
TYR A 147
 None
 1.26A 3apwB-6ey4A:
undetectable		 3apwB-6ey4A:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DX5_B_MIYB1103_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 6ey4 GLDM
(Flavobacterium
johnsoniae) 		6 / 12 GLY A 370
ASN A 354
ILE A 356
ALA A 358
VAL A 386
PHE A 348
 None
 1.43A 4dx5B-6ey4A:
4.8		 4dx5B-6ey4A:
5.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U8V_B_MIYB1103_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 6ey4 GLDM
(Flavobacterium
johnsoniae) 		6 / 12 GLY A 370
ASN A 354
ILE A 356
ALA A 358
VAL A 386
PHE A 348
 None
 1.47A 4u8vB-6ey4A:
3.7		 4u8vB-6ey4A:
5.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U8Y_B_MIYB1102_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 6ey4 GLDM
(Flavobacterium
johnsoniae) 		6 / 12 GLY A 370
ASN A 354
ILE A 356
ALA A 358
VAL A 386
PHE A 348
 None
 1.41A 4u8yB-6ey4A:
4.8		 4u8yB-6ey4A:
5.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U95_B_MIYB1102_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 6ey4 GLDM
(Flavobacterium
johnsoniae) 		6 / 12 GLY A 370
ASN A 354
ILE A 356
ALA A 358
VAL A 386
PHE A 348
 None
 1.42A 4u95B-6ey4A:
3.5		 4u95B-6ey4A:
5.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GSN_A_MMZA503_1
(FLAVIN-CONTAINING
MONOOXYGENASE)		 6ey4 GLDM
(Flavobacterium
johnsoniae) 		3 / 3 ASN A  47
SER A  50
SER A  49
 None
 0.79A 5gsnA-6ey4A:
undetectable		 5gsnA-6ey4A:
10.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH8_A_ACTA302_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 6ey4 GLDM
(Flavobacterium
johnsoniae) 		3 / 3 CYH A 472
MET A 453
ASN A 452
 None
 1.12A 5qh8A-6ey4A:
undetectable		 5qh8A-6ey4A:
undetectable