SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6eyy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_A_CHDA1502_0
(FERROCHELATASE)		 6eyy ACRIIA6
(Streptococcus
phage
73) 		4 / 8 ARG A 111
LEU A 107
VAL A 136
GLY A 116
 None
 1.03A 1hrkA-6eyyA:
undetectable		 1hrkA-6eyyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_B_CHDB2502_0
(FERROCHELATASE)		 6eyy ACRIIA6
(Streptococcus
phage
73) 		4 / 8 ARG A 111
LEU A 107
VAL A 136
GLY A 116
 None
 1.01A 1hrkB-6eyyA:
undetectable		 1hrkB-6eyyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIN_A_TFPA155_1
(CALMODULIN)		 6eyy ACRIIA6
(Streptococcus
phage
73) 		4 / 7 GLN A 151
GLU A  68
PHE A  25
MET A 121
 None
 1.01A 1linA-6eyyA:
undetectable		 1linA-6eyyA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q2H_B_ACTB501_0
(SECRETION CHAPERONE,
PHAGE-DISPLAY
DERIVED PEPTIDE)		 6eyy ACRIIA6
(Streptococcus
phage
73) 		3 / 3 ARG A  17
SER A  16
TYR A 157
 None
 0.90A 2q2hA-6eyyA:
undetectable
2q2hB-6eyyA:
undetectable		 2q2hA-6eyyA:
undetectable
2q2hB-6eyyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWX_A_EPAA1_2
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))		 6eyy ACRIIA6
(Streptococcus
phage
73) 		5 / 12 LEU A  12
ILE A   3
ILE A  48
MET A   1
LEU A  69
 None
 1.25A 3gwxA-6eyyA:
undetectable		 3gwxA-6eyyA:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_B_ADNB401_1
(PUTATIVE ADENOSINE
KINASE)		 6eyy ACRIIA6
(Streptococcus
phage
73) 		5 / 12 LEU A 179
GLY A 117
GLY A 116
LEU A 103
GLY A 167
 None
 1.10A 3vasB-6eyyA:
undetectable		 3vasB-6eyyA:
12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_C_STRC601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 6eyy ACRIIA6
(Streptococcus
phage
73) 		4 / 5 ILE A 175
ARG A 168
ASP A 113
GLU A 176
 None
 1.24A 4nkxC-6eyyA:
undetectable		 4nkxC-6eyyA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_D_STRD601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 6eyy ACRIIA6
(Streptococcus
phage
73) 		4 / 5 ILE A 175
ARG A 168
ASP A 113
GLU A 176
 None
 1.21A 4nkxD-6eyyA:
undetectable		 4nkxD-6eyyA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1Y_B_LOCB502_1
(TUBULIN BETA CHAIN)		 6eyy ACRIIA6
(Streptococcus
phage
73) 		5 / 12 LEU A 104
LEU A 179
ASN A 177
VAL A 136
ILE A 182
 None
 1.15A 4x1yB-6eyyA:
undetectable		 4x1yB-6eyyA:
12.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4D_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 6eyy ACRIIA6
(Streptococcus
phage
73) 		4 / 5 TYR A  79
LEU A  10
GLU A   9
TYR A  92
 None
 1.45A 4z4dA-6eyyA:
undetectable		 4z4dA-6eyyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4H_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 6eyy ACRIIA6
(Streptococcus
phage
73) 		4 / 5 TYR A  79
LEU A  10
GLU A   9
TYR A  92
 None
 1.47A 4z4hA-6eyyA:
undetectable		 4z4hA-6eyyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CBD_A_TRPA901_0
(PROTEIN ARGONAUTE-2)		 6eyy ACRIIA6
(Streptococcus
phage
73) 		4 / 5 TYR A  79
LEU A  10
GLU A   9
TYR A  92
 None
 1.47A 6cbdA-6eyyA:
undetectable		 6cbdA-6eyyA:
undetectable