SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6ezn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZM_A_BZMA600_0
(ODORANT-BINDING
PROTEIN)		 6ezn DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT WBP1
(Saccharomyces
cerevisiae) 		4 / 8 ILE G 232
ASN G 242
ASN G 246
LEU G 254
 None
 0.78A 1dzmA-6eznG:
undetectable		 1dzmA-6eznG:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_D_DESD600_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 6ezn DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT WBP1
(Saccharomyces
cerevisiae) 		5 / 12 LEU G 364
GLU G 252
ARG G 167
HIS G 307
ILE G 264
 None
 1.06A 1s9pD-6eznG:
undetectable		 1s9pD-6eznG:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEI_A_CXXA802_1
(TRANSPORTER)		 6ezn DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT OST2
DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT WBP1
(Saccharomyces
cerevisiae) 		4 / 6 SER B 118
PHE G 409
ILE B  47
PHE G 413
 None
 1.25A 2qeiA-6eznB:
undetectable		 2qeiA-6eznB:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_J_TFPJ202_1
(PROTEIN S100-A4)		 6ezn DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT WBP1
(Saccharomyces
cerevisiae) 		5 / 11 LEU G 110
LEU G 238
SER G 235
PHE G 237
ILE G 232
 None
 1.27A 3ko0A-6eznG:
undetectable
3ko0B-6eznG:
undetectable
3ko0I-6eznG:
undetectable
3ko0J-6eznG:
undetectable		 3ko0A-6eznG:
27.17
3ko0B-6eznG:
27.17
3ko0I-6eznG:
27.17
3ko0J-6eznG:
27.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OND_A_ADNA506_2
(ADENOSYLHOMOCYSTEINA
SE)		 6ezn DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT WBP1
(Saccharomyces
cerevisiae) 		3 / 3 GLN G 214
THR G 210
LEU G 192
 None
 0.75A 3ondA-6eznG:
undetectable		 3ondA-6eznG:
8.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OND_B_ADNB507_2
(ADENOSYLHOMOCYSTEINA
SE)		 6ezn DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT WBP1
(Saccharomyces
cerevisiae) 		3 / 3 GLN G 214
THR G 210
LEU G 192
 None
 0.75A 3ondB-6eznG:
2.2		 3ondB-6eznG:
8.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OWX_A_XRAA233_2
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 6ezn DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT WBP1
(Saccharomyces
cerevisiae) 		4 / 5 VAL G  28
PHE G 102
ILE G 109
PHE G 103
 None
 0.89A 3owxB-6eznG:
3.8		 3owxB-6eznG:
16.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SPK_B_TPVB100_1
(HIV-1 PROTEASE)		 6ezn DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT WBP1
(Saccharomyces
cerevisiae) 		5 / 9 VAL G 118
GLY G 233
ILE G 232
PRO G  83
THR G  84
 None
 1.11A 3spkA-6eznG:
undetectable		 3spkA-6eznG:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IB4_A_ERMA2001_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 6ezn DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT OST2
(Saccharomyces
cerevisiae) 		4 / 7 ASP B  48
LEU B  91
GLN B  97
LEU B  98
 None
 1.00A 4ib4A-6eznB:
4.0		 4ib4A-6eznB:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1E_A_C2FA3000_0
(DIHYDROPTEROATE
SYNTHASE DHPS)		 6ezn DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT WBP1
(Saccharomyces
cerevisiae) 		5 / 12 LEU G 126
GLY G 233
SER G 235
ILE G 232
ASN G 242
 None
 0.97A 4o1eA-6eznG:
undetectable		 4o1eA-6eznG:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1E_B_C2FB4000_0
(DIHYDROPTEROATE
SYNTHASE DHPS)		 6ezn DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT WBP1
(Saccharomyces
cerevisiae) 		5 / 12 LEU G 126
GLY G 233
SER G 235
ILE G 232
ASN G 242
 None
 1.00A 4o1eB-6eznG:
undetectable		 4o1eB-6eznG:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_D_ACTD201_0
(RETINOL-BINDING
PROTEIN 2)		 6ezn DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT WBP1
(Saccharomyces
cerevisiae) 		3 / 3 ASP G 288
HIS G 273
LYS G 289
 None
 1.02A 4qzuD-6eznG:
undetectable		 4qzuD-6eznG:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBS_A_DIFA502_1
(PENTALENIC ACID
SYNTHASE)		 6ezn DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT WBP1
(Saccharomyces
cerevisiae) 		5 / 9 LEU G  57
LEU G  44
THR G  26
LEU G  27
ILE G  80
 None
 1.35A 4ubsA-6eznG:
undetectable		 4ubsA-6eznG:
11.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_S_BEZS801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 6ezn DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT WBP1
(Saccharomyces
cerevisiae) 		4 / 6 PHE G 174
SER G 154
HIS G 157
LEU G 151
 None
 1.34A 5dzke-6eznG:
undetectable
5dzks-6eznG:
undetectable		 5dzke-6eznG:
undetectable
5dzks-6eznG:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MQT_C_STIC302_1
(DEOXYCYTIDINE KINASE)		 6ezn DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT WBP1
(Saccharomyces
cerevisiae) 		5 / 12 GLU G 183
GLU G 106
GLN G 187
LEU G 224
GLU G 128
 None
 1.37A 5mqtC-6eznG:
undetectable		 5mqtC-6eznG:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBF_A_ACTA507_0
(MOLYBDOPTERIN
BIOSYNTHESIS PROTEIN
CNX1)		 6ezn DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE--PROTE
IN
GLYCOSYLTRANSFERASE
SUBUNIT WBP1
(Saccharomyces
cerevisiae) 		3 / 3 LYS G 136
SER G 178
SER G 113
 None
 1.12A 6gbfA-6eznG:
2.8		 6gbfA-6eznG:
undetectable