SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6f0x'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ISM_B_NCAB305_0
(BONE MARROW STROMAL
CELL ANTIGEN 1)		 6f0x MAD2L1-BINDING
PROTEIN
(Homo
sapiens) 		4 / 7 LEU P 172
SER P 170
ASP P 168
PHE P  60
 None
 1.18A 1ismB-6f0xP:
undetectable		 1ismB-6f0xP:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DXR_A_SORA1002_0
(LACTOTRANSFERRIN)		 6f0x MAD2L1-BINDING
PROTEIN
(Homo
sapiens) 		3 / 3 THR P 145
PRO P 148
TYR P 260
 None
 0.94A 2dxrA-6f0xP:
undetectable		 2dxrA-6f0xP:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Z_A_FLPA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 6f0x MAD2L1-BINDING
PROTEIN
(Homo
sapiens) 		5 / 12 VAL P 134
LEU P 153
LEU P  77
TYR P 232
ALA P 265
 None
 0.99A 3n8zA-6f0xP:
undetectable		 3n8zA-6f0xP:
12.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)		 6f0x MAD2L1-BINDING
PROTEIN
(Homo
sapiens) 		4 / 5 THR P 145
VAL P 150
PRO P 148
TYR P 260
 None
 1.18A 4grkA-6f0xP:
undetectable		 4grkA-6f0xP:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JM4_A_BEZA301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 6f0x MAD2L1-BINDING
PROTEIN
(Homo
sapiens) 		4 / 5 ILE P 152
MET P  81
GLN P  86
ARG P  84
 None
 1.29A 5jm4A-6f0xP:
undetectable		 5jm4A-6f0xP:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MWY_A_YNUA1101_1
(MINERALOCORTICOID
RECEPTOR)		 6f0x MAD2L1-BINDING
PROTEIN
(Homo
sapiens) 		4 / 6 GLN P 179
PHE P  60
CYH P  74
PHE P 142
 None
 1.08A 5mwyA-6f0xP:
undetectable		 5mwyA-6f0xP:
undetectable