SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6f1d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQF_A_SAMA430_1
(SUN PROTEIN)		 6f1d COMPLEMENT C1R
SUBCOMPONENT
(Homo
sapiens) 		3 / 3 PRO A 199
ASP A 236
ASP A 277
 None
CA  A 300 (-2.2A)
None
 0.77A 1sqfA-6f1dA:
undetectable		 1sqfA-6f1dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYU_A_SAMA201_1
(PUTATIVE RIBOSOMAL
RNA
METHYLTRANSFERASE 2)		 6f1d COMPLEMENT C1R
SUBCOMPONENT
(Homo
sapiens) 		4 / 4 PRO A 199
ASP A 236
ASP A 227
ASP A 277
 None
CA  A 300 (-2.2A)
None
None
 1.16A 2nyuA-6f1dA:
undetectable		 2nyuA-6f1dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYU_B_SAMB201_1
(PUTATIVE RIBOSOMAL
RNA
METHYLTRANSFERASE 2)		 6f1d COMPLEMENT C1R
SUBCOMPONENT
(Homo
sapiens) 		4 / 5 PRO A 199
ASP A 236
ASP A 227
ASP A 277
 None
CA  A 300 (-2.2A)
None
None
 1.19A 2nyuB-6f1dA:
undetectable		 2nyuB-6f1dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V81_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 6f1d COMPLEMENT C1R
SUBCOMPONENT
(Homo
sapiens) 		4 / 8 LEU A 283
VAL A 266
TYR A 205
TYR A 181
 None
 1.12A 3v81C-6f1dA:
undetectable		 3v81C-6f1dA:
9.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1001_1
(HEMOLYTIC LECTIN
CEL-III)		 6f1d COMPLEMENT C1R
SUBCOMPONENT
(Homo
sapiens) 		4 / 5 ASP A 236
GLY A 276
TYR A 235
ASP A 273
 CA  A 300 (-2.2A)
CA  A 300 ( 4.5A)
None
CA  A 300 (-3.1A)
 1.30A 3w9tA-6f1dA:
undetectable		 3w9tA-6f1dA:
11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB503_1
(HEMOLYTIC LECTIN
CEL-III)		 6f1d COMPLEMENT C1R
SUBCOMPONENT
(Homo
sapiens) 		4 / 5 ASP A 236
GLY A 276
TYR A 235
ASP A 273
 CA  A 300 (-2.2A)
CA  A 300 ( 4.5A)
None
CA  A 300 (-3.1A)
 1.31A 3w9tB-6f1dA:
undetectable		 3w9tB-6f1dA:
11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1001_1
(HEMOLYTIC LECTIN
CEL-III)		 6f1d COMPLEMENT C1R
SUBCOMPONENT
(Homo
sapiens) 		4 / 5 ASP A 236
GLY A 276
TYR A 235
ASP A 273
 CA  A 300 (-2.2A)
CA  A 300 ( 4.5A)
None
CA  A 300 (-3.1A)
 1.30A 3w9tC-6f1dA:
undetectable		 3w9tC-6f1dA:
11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1005_1
(HEMOLYTIC LECTIN
CEL-III)		 6f1d COMPLEMENT C1R
SUBCOMPONENT
(Homo
sapiens) 		3 / 3 ASP A 273
GLY A 276
TYR A 235
 CA  A 300 (-3.1A)
CA  A 300 ( 4.5A)
None
 0.73A 3w9tC-6f1dA:
undetectable		 3w9tC-6f1dA:
11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD502_1
(HEMOLYTIC LECTIN
CEL-III)		 6f1d COMPLEMENT C1R
SUBCOMPONENT
(Homo
sapiens) 		4 / 5 ASP A 236
GLY A 276
TYR A 235
ASP A 273
 CA  A 300 (-2.2A)
CA  A 300 ( 4.5A)
None
CA  A 300 (-3.1A)
 1.31A 3w9tD-6f1dA:
undetectable		 3w9tD-6f1dA:
11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE504_1
(HEMOLYTIC LECTIN
CEL-III)		 6f1d COMPLEMENT C1R
SUBCOMPONENT
(Homo
sapiens) 		4 / 5 ASP A 236
GLY A 276
TYR A 235
ASP A 273
 CA  A 300 (-2.2A)
CA  A 300 ( 4.5A)
None
CA  A 300 (-3.1A)
 1.31A 3w9tE-6f1dA:
undetectable		 3w9tE-6f1dA:
11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF504_1
(HEMOLYTIC LECTIN
CEL-III)		 6f1d COMPLEMENT C1R
SUBCOMPONENT
(Homo
sapiens) 		4 / 5 ASP A 236
GLY A 276
TYR A 235
ASP A 273
 CA  A 300 (-2.2A)
CA  A 300 ( 4.5A)
None
CA  A 300 (-3.1A)
 1.31A 3w9tF-6f1dA:
undetectable		 3w9tF-6f1dA:
11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG503_1
(HEMOLYTIC LECTIN
CEL-III)		 6f1d COMPLEMENT C1R
SUBCOMPONENT
(Homo
sapiens) 		3 / 3 ASP A 273
GLY A 276
TYR A 235
 CA  A 300 (-3.1A)
CA  A 300 ( 4.5A)
None
 0.73A 3w9tG-6f1dA:
undetectable		 3w9tG-6f1dA:
11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG504_1
(HEMOLYTIC LECTIN
CEL-III)		 6f1d COMPLEMENT C1R
SUBCOMPONENT
(Homo
sapiens) 		4 / 5 ASP A 236
GLY A 276
TYR A 235
ASP A 273
 CA  A 300 (-2.2A)
CA  A 300 ( 4.5A)
None
CA  A 300 (-3.1A)
 1.31A 3w9tG-6f1dA:
undetectable		 3w9tG-6f1dA:
11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K17_B_OHBB701_0
(LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A)		 6f1d COMPLEMENT C1R
SUBCOMPONENT
(Homo
sapiens) 		4 / 5 GLU A 192
SER A 190
ARG A 195
SER A 189
 None
NA  A 301 (-2.8A)
None
None
 1.26A 4k17B-6f1dA:
undetectable		 4k17B-6f1dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		 6f1d COMPLEMENT C1R
SUBCOMPONENT
(Homo
sapiens) 		4 / 7 LYS A 218
LEU A 220
THR A 286
SER A 189
 None
 0.97A 4pwjB-6f1dA:
undetectable		 4pwjB-6f1dA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V30_B_LVYB151_1
(CEREBLON ISOFORM 4)		 6f1d COMPLEMENT C1R
SUBCOMPONENT
(Homo
sapiens) 		4 / 8 PRO A 256
PHE A 250
TRP A 281
TYR A 197
 None
 1.36A 4v30B-6f1dA:
undetectable		 4v30B-6f1dA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH1_B_EF2B202_0
(CEREBLON ISOFORM 4)		 6f1d COMPLEMENT C1R
SUBCOMPONENT
(Homo
sapiens) 		4 / 7 PRO A 256
PHE A 250
TRP A 281
TYR A 197
 None
 1.41A 5oh1B-6f1dA:
undetectable		 5oh1B-6f1dA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH1_C_9UQC202_0
(CEREBLON ISOFORM 4)		 6f1d COMPLEMENT C1R
SUBCOMPONENT
(Homo
sapiens) 		4 / 8 PRO A 256
PHE A 250
TRP A 281
TYR A 197
 None
 1.35A 5oh1C-6f1dA:
undetectable		 5oh1C-6f1dA:
undetectable