SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6f1e'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SKX_A_RFPA1_2
(ORPHAN NUCLEAR
RECEPTOR PXR)		 6f1e INTERFERON GAMMA
(Paralichthys
olivaceus) 		4 / 5 LYS A 122
PHE A  55
LEU A 126
LEU A  38
 None
 1.31A 1skxA-6f1eA:
undetectable		 1skxA-6f1eA:
14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 6f1e INTERFERON GAMMA
(Paralichthys
olivaceus) 		3 / 3 ARG A 181
GLU A  65
THR A  66
 None
 0.80A 3v4tA-6f1eA:
undetectable		 3v4tA-6f1eA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDH_A_DAHA60_1
(PUTATIVE CYTOCHROME
C)		 6f1e INTERFERON GAMMA
(Paralichthys
olivaceus) 		4 / 6 HIS A  40
MET A  85
ASN A  91
LEU A 116
 None
 1.33A 5xdhA-6f1eA:
undetectable
5xdhC-6f1eA:
undetectable		 5xdhA-6f1eA:
21.18
5xdhC-6f1eA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDH_B_DAHB60_1
(PUTATIVE CYTOCHROME
C)		 6f1e INTERFERON GAMMA
(Paralichthys
olivaceus) 		4 / 5 HIS A  40
MET A  85
ASN A  91
LEU A 116
 None
 1.20A 5xdhB-6f1eA:
undetectable		 5xdhB-6f1eA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDH_D_DAHD60_1
(PUTATIVE CYTOCHROME
C)		 6f1e INTERFERON GAMMA
(Paralichthys
olivaceus) 		4 / 5 HIS A  40
MET A  85
ASN A  91
LEU A 116
 None
 1.10A 5xdhD-6f1eA:
undetectable		 5xdhD-6f1eA:
21.18