SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6f1j'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_B_115B1_2
(HMG-COA REDUCTASE)		 6f1j -
(-) 		4 / 8 ARG A 240
SER A 256
ASN A 208
ASP A 205
 None
 1.22A 1hwiB-6f1jA:
undetectable		 1hwiB-6f1jA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_A_117A2_1
(HMG-COA REDUCTASE)		 6f1j -
(-) 		4 / 8 ARG A 240
SER A 256
ASN A 208
ASP A 205
 None
 1.26A 1hwkA-6f1jA:
undetectable		 1hwkA-6f1jA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_C_117C4_1
(HMG-COA REDUCTASE)		 6f1j -
(-) 		4 / 8 ARG A 240
SER A 256
ASN A 208
ASP A 205
 None
 1.23A 1hwkC-6f1jA:
undetectable		 1hwkC-6f1jA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_D_117D3_2
(HMG-COA REDUCTASE)		 6f1j -
(-) 		4 / 8 ARG A 240
SER A 256
ASN A 208
ASP A 205
 None
 1.24A 1hwkD-6f1jA:
undetectable		 1hwkD-6f1jA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A8T_B_ADNB252_1
(U8 SNORNA-BINDING
PROTEIN X29)		 6f1j -
(-) 		4 / 8 HIS A 180
GLY A 176
ILE A 151
SER A 154
 ZN  A 406 (-3.3A)
None
None
None
 1.03A 2a8tB-6f1jA:
undetectable		 2a8tB-6f1jA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A3Y_A_OBNA6000_1
(NA, K-ATPASE ALPHA
SUBUNIT)		 6f1j -
(-) 		5 / 10 PHE A 174
ALA A 103
PHE A 126
LEU A 146
THR A 105
 None
EDG  A 401 (-3.6A)
None
None
None
 1.21A 3a3yA-6f1jA:
undetectable		 3a3yA-6f1jA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAK_A_EV1A415_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 6f1j -
(-) 		5 / 9 TYR A 128
MET A 186
ILE A 116
PHE A 107
ILE A 188
 None
 1.46A 3iakA-6f1jA:
undetectable		 3iakA-6f1jA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_2
(GENOME POLYPROTEIN)		 6f1j -
(-) 		4 / 4 PHE A 107
TYR A 119
VAL A 282
LEU A 281
 None
 1.47A 3keeD-6f1jA:
undetectable		 3keeD-6f1jA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 6f1j -
(-) 		3 / 3 GLY A 248
TRP A 251
VAL A 202
 None
 0.71A 3n62B-6f1jA:
undetectable		 3n62B-6f1jA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N65_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 6f1j -
(-) 		3 / 3 GLY A 248
TRP A 251
VAL A 202
 None
 0.73A 3n65B-6f1jA:
undetectable		 3n65B-6f1jA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N66_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 6f1j -
(-) 		3 / 3 GLY A 248
TRP A 251
VAL A 202
 None
 0.72A 3n66B-6f1jA:
undetectable		 3n66B-6f1jA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NAI_C_URFC521_1
(RNA DEPENDENT RNA
POLYMERASE)		 6f1j -
(-) 		4 / 5 ARG A  51
ASP A 160
ASP A 177
ARG A 237
 EDG  A 401 (-4.4A)
EDG  A 401 (-2.9A)
None
PEG  A 403 (-4.6A)
 1.25A 3naiC-6f1jA:
undetectable		 3naiC-6f1jA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_A_ADNA401_1
(ADENOSINE KINASE)		 6f1j -
(-) 		5 / 12 ASN A 267
LEU A 324
GLY A 269
ALA A 325
GLY A  38
 None
 1.13A 4n09A-6f1jA:
undetectable		 4n09A-6f1jA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V20_A_ACTA1444_0
(CELLOBIOHYDROLASE)		 6f1j -
(-) 		4 / 5 GLY A 179
THR A 207
HIS A 180
GLY A 153
 None
None
ZN  A 406 (-3.3A)
None
 1.12A 4v20A-6f1jA:
undetectable		 4v20A-6f1jA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_P_BEZP801_1
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 6f1j -
(-) 		4 / 6 PHE A 211
ALA A 175
HIS A 180
LEU A 210
 PEG  A 403 ( 4.7A)
None
ZN  A 406 (-3.3A)
None
 1.16A 5dzkB-6f1jA:
undetectable
5dzkP-6f1jA:
undetectable		 5dzkB-6f1jA:
undetectable
5dzkP-6f1jA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 6f1j -
(-) 		4 / 4 SER A  36
ALA A 270
GLN A 318
THR A 273
 None
 1.49A 5n0xA-6f1jA:
undetectable		 5n0xA-6f1jA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_ACTB804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6f1j -
(-) 		3 / 3 GLY A 248
TRP A 251
VAL A 202
 None
 0.73A 5vuoB-6f1jA:
undetectable		 5vuoB-6f1jA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DHB_A_BEZA202_0
(HEPATITIS A VIRUS
CELLULAR RECEPTOR 2)		 6f1j -
(-) 		4 / 6 ILE A 188
MET A 170
ASN A 169
ASP A 166
 None
 1.27A 6dhbA-6f1jA:
undetectable		 6dhbA-6f1jA:
undetectable