SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6f1s'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V2O_B_CLQB1079_0 (SAPOSIN-B)	6f1s	CGLIIR PROTEIN (Corynebacterium glutamicum)	3 / 3	MET A 516 GLU A 546 LEU A 552	None	0.73A	4v2oB-6f1sA: undetectable	4v2oB-6f1sA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XDQ_A_BEZA306_0 (GLYCOSIDE HYDROLASE FAMILY PROTEIN)	6f1s	CGLIIR PROTEIN (Corynebacterium glutamicum)	3 / 3	ARG A 593 ASP A 498 TRP A 615	FMT A 701 ( 4.7A) None None	1.17A	4xdqA-6f1sA: undetectable	4xdqA-6f1sA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4YIA_B_IMNB401_1 (THYROXINE-BINDING GLOBULIN)	6f1s	CGLIIR PROTEIN (Corynebacterium glutamicum)	5 / 10	SER A 611 SER A 610 LEU A 501 LEU A 591 LEU A 523	None	1.06A	4yiaA-6f1sA: undetectable	4yiaA-6f1sA: 12.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UIG_A_EDTA501_0 (ADENOSINE RECEPTOR A2A,SOLUBLE CYTOCHROME B562,ADENOSINE RECEPTOR A2A)	6f1s	CGLIIR PROTEIN (Corynebacterium glutamicum)	4 / 6	ASN A 598 THR A 608 ILE A 594 GLU A 595	None None None FMT A 701 ( 3.9A)	1.32A	5uigA-6f1sA: undetectable	5uigA-6f1sA: undetectable

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["4V2O_B_CLQB1079_0","SAPOSIN-B","6f1s","CGLIIR PROTEIN","Corynebacterium glutamicum",3,"MET A 516;GLU A 546;LEU A 552","None","0.73A","4v2oB-6f1sA:undetectable","4v2oB-6f1sA:undetectable"],["4XDQ_A_BEZA306_0","GLYCOSIDE HYDROLASE FAMILY PROTEIN","6f1s","CGLIIR PROTEIN","Corynebacterium glutamicum",3,"ARG A 593;ASP A 498;TRP A 615","FMT A 701 ( 4.7A);None;None","1.17A","4xdqA-6f1sA:undetectable","4xdqA-6f1sA:undetectable"],["4YIA_B_IMNB401_1","THYROXINE-BINDING GLOBULIN;THYROXINE-BINDING GLOBULIN","6f1s","CGLIIR PROTEIN","Corynebacterium glutamicum",5,"SER A 611;SER A 610;LEU A 501;LEU A 591;LEU A 523","None","1.06A","4yiaA-6f1sA:undetectable","4yiaA-6f1sA:12.36"],["5UIG_A_EDTA501_0","ADENOSINE RECEPTOR A2A,SOLUBLE CYTOCHROME B562,ADENOSINE RECEPTOR A2A","6f1s","CGLIIR PROTEIN","Corynebacterium glutamicum",4,"ASN A 598;THR A 608;ILE A 594;GLU A 595","None;None;None;FMT A 701 ( 3.9A)","1.32A","5uigA-6f1sA:undetectable","5uigA-6f1sA:undetectable"]]