SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6f1t'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QD3_A_CHDA502_0 (FERROCHELATASE)	6f1t	CYTOPLASMIC DYNEIN 1 HEAVY CHAIN 1,CYTOPLASMIC DYNEIN 1 HEAVY CHAIN 1,CYTOPLASMIC DYNEIN 1 HEAVY CHAIN 1,DYNEIN HEAVY CHAIN,CYTOPLASMIC DYNEIN 1 HEAVY CHAIN 1,CYTOPLASMIC DYNEIN 1 HEAVY CHAIN 1,CYTOPLASMIC DYNEIN 1 HEAVY CHAIN 1,CYTOPLASMIC DYNEIN 1 HEAVY CHAIN 1,DYNEIN HEAVY CHAIN,CYTOPLASMIC DYNEIN 1 HEAVY CHAIN 1,CYTOPLASMIC DYNEIN 1 HEAVY CHAIN 1 (Homo sapiens)	4 / 8	ARG e 309 VAL e 249 GLY e 248 TRP e 252	None	1.14A	2qd3A-6f1te: undetectable	2qd3A-6f1te: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2RLF_A_RIMA199_1 (MATRIX PROTEIN 2)	6f1t	CYTOPLASMIC DYNEIN 1 HEAVY CHAIN 1,CYTOPLASMIC DYNEIN 1 HEAVY CHAIN 1,CYTOPLASMIC DYNEIN 1 HEAVY CHAIN 1,DYNEIN HEAVY CHAIN,CYTOPLASMIC DYNEIN 1 HEAVY CHAIN 1,CYTOPLASMIC DYNEIN 1 HEAVY CHAIN 1,CYTOPLASMIC DYNEIN 1 HEAVY CHAIN 1,CYTOPLASMIC DYNEIN 1 HEAVY CHAIN 1,DYNEIN HEAVY CHAIN,CYTOPLASMIC DYNEIN 1 HEAVY CHAIN 1,CYTOPLASMIC DYNEIN 1 HEAVY CHAIN 1 (Homo sapiens)	4 / 6	LEU e 285 LEU e 281 ILE e 288 ARG e 287	None	0.96A	2rlfA-6f1te: undetectable 2rlfB-6f1te: undetectable	2rlfA-6f1te: 24.05 2rlfB-6f1te: 24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2RLF_C_RIMC399_1 (MATRIX PROTEIN 2)	6f1t	CYTOPLASMIC DYNEIN 1 HEAVY CHAIN 1,CYTOPLASMIC DYNEIN 1 HEAVY CHAIN 1,CYTOPLASMIC DYNEIN 1 HEAVY CHAIN 1,DYNEIN HEAVY CHAIN,CYTOPLASMIC DYNEIN 1 HEAVY CHAIN 1,CYTOPLASMIC DYNEIN 1 HEAVY CHAIN 1,CYTOPLASMIC DYNEIN 1 HEAVY CHAIN 1,CYTOPLASMIC DYNEIN 1 HEAVY CHAIN 1,DYNEIN HEAVY CHAIN,CYTOPLASMIC DYNEIN 1 HEAVY CHAIN 1,CYTOPLASMIC DYNEIN 1 HEAVY CHAIN 1 (Homo sapiens)	4 / 6	LEU e 285 LEU e 281 ILE e 288 ARG e 287	None	0.96A	2rlfC-6f1te: undetectable 2rlfD-6f1te: undetectable	2rlfC-6f1te: 24.05 2rlfD-6f1te: 24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2X8O_A_OINA1314_1 (CHOLINE-BINDING PROTEIN F)	6f1t	BICD FAMILY-LIKE CARGO ADAPTER 1,BICD FAMILY-LIKE CARGO ADAPTER 1,BICD FAMILY-LIKE CARGO ADAPTER 1,BICDR-1 (Mus musculus)	4 / 5	LYS X 198 ASP X 195 ARG X 196 GLU X 193	None	1.33A	2x8oA-6f1tX: undetectable	2x8oA-6f1tX: 12.54

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2QD3_A_CHDA502_0","FERROCHELATASE","6f1t","CYTOPLASMIC DYNEIN 1 HEAVY CHAIN 1,CYTOPLASMIC DYNEIN 1 HEAVY CHAIN 1,CYTOPLASMIC DYNEIN 1 HEAVY CHAIN 1,DYNEIN HEAVY CHAIN,CYTOPLASMIC DYNEIN 1 HEAVY CHAIN 1,CYTOPLASMIC DYNEIN 1 HEAVY CHAIN 1,CYTOPLASMIC DYNEIN 1 HEAVY CHAIN 1,CYTOPLASMIC DYNEIN 1 HEAVY CHAIN 1,DYNEIN HEAVY CHAIN,CYTOPLASMIC DYNEIN 1 HEAVY CHAIN 1,CYTOPLASMIC DYNEIN 1 HEAVY CHAIN 1","Homo sapiens",4,"ARG e 309;VAL e 249;GLY e 248;TRP e 252","None","1.14A","2qd3A-6f1te:undetectable","2qd3A-6f1te:undetectable"],["2RLF_A_RIMA199_1","MATRIX PROTEIN 2;MATRIX PROTEIN 2","6f1t","CYTOPLASMIC DYNEIN 1 HEAVY CHAIN 1,CYTOPLASMIC DYNEIN 1 HEAVY CHAIN 1,CYTOPLASMIC DYNEIN 1 HEAVY CHAIN 1,DYNEIN HEAVY CHAIN,CYTOPLASMIC DYNEIN 1 HEAVY CHAIN 1,CYTOPLASMIC DYNEIN 1 HEAVY CHAIN 1,CYTOPLASMIC DYNEIN 1 HEAVY CHAIN 1,CYTOPLASMIC DYNEIN 1 HEAVY CHAIN 1,DYNEIN HEAVY CHAIN,CYTOPLASMIC DYNEIN 1 HEAVY CHAIN 1,CYTOPLASMIC DYNEIN 1 HEAVY CHAIN 1","Homo sapiens",4,"LEU e 285;LEU e 281;ILE e 288;ARG e 287","None","0.96A","2rlfA-6f1te:undetectable;2rlfB-6f1te:undetectable","2rlfA-6f1te:24.05;2rlfB-6f1te:24.05"],["2RLF_C_RIMC399_1","MATRIX PROTEIN 2;MATRIX PROTEIN 2","6f1t","CYTOPLASMIC DYNEIN 1 HEAVY CHAIN 1,CYTOPLASMIC DYNEIN 1 HEAVY CHAIN 1,CYTOPLASMIC DYNEIN 1 HEAVY CHAIN 1,DYNEIN HEAVY CHAIN,CYTOPLASMIC DYNEIN 1 HEAVY CHAIN 1,CYTOPLASMIC DYNEIN 1 HEAVY CHAIN 1,CYTOPLASMIC DYNEIN 1 HEAVY CHAIN 1,CYTOPLASMIC DYNEIN 1 HEAVY CHAIN 1,DYNEIN HEAVY CHAIN,CYTOPLASMIC DYNEIN 1 HEAVY CHAIN 1,CYTOPLASMIC DYNEIN 1 HEAVY CHAIN 1","Homo sapiens",4,"LEU e 285;LEU e 281;ILE e 288;ARG e 287","None","0.96A","2rlfC-6f1te:undetectable;2rlfD-6f1te:undetectable","2rlfC-6f1te:24.05;2rlfD-6f1te:24.05"],["2X8O_A_OINA1314_1","CHOLINE-BINDING PROTEIN F","6f1t","BICD FAMILY-LIKE CARGO ADAPTER 1,BICD FAMILY-LIKE CARGO ADAPTER 1,BICD FAMILY-LIKE CARGO ADAPTER 1,BICDR-1","Mus musculus",4,"LYS X 198;ASP X 195;ARG X 196;GLU X 193","None","1.33A","2x8oA-6f1tX:undetectable","2x8oA-6f1tX:12.54"]]