SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6f1v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GXS_A_BEZA601_0
(P-(S)-HYDROXYMANDELO
NITRILE LYASE CHAIN
A
P-(S)-HYDROXYMANDELO
NITRILE LYASE CHAIN
B)		 6f1v CYTOPLASMIC DYNEIN 1
HEAVY CHAIN 1
(Homo
sapiens) 		4 / 7 GLY f 646
PRO f 643
SER f 636
HIS f 637
 None
 0.62A 1gxsA-6f1vf:
undetectable
1gxsB-6f1vf:
undetectable		 1gxsA-6f1vf:
undetectable
1gxsB-6f1vf:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CL9_A_MTXA602_2
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE (DHFR-TS))		 6f1v CYTOPLASMIC DYNEIN 1
HEAVY CHAIN 1
(Homo
sapiens) 		4 / 4 VAL f 644
ARG f 704
ILE f 764
THR f 695
 None
 1.39A 3cl9A-6f1vf:
undetectable		 3cl9A-6f1vf:
11.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_A_ZPCA1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 6f1v CYTOPLASMIC DYNEIN 1
HEAVY CHAIN 1
(Homo
sapiens) 		4 / 7 TYR f 527
VAL f 523
ILE f 520
ASN f 524
 None
 1.06A 4a97E-6f1vf:
5.5		 4a97E-6f1vf:
12.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MGH_A_ACTA1320_0
(PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
SYNTHASE)		 6f1v CYTOPLASMIC DYNEIN 1
HEAVY CHAIN 1
(Homo
sapiens) 		4 / 5 VAL f 665
LEU f 682
ILE f 609
LEU f 608
 None
 0.78A 4mghA-6f1vf:
undetectable		 4mghA-6f1vf:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZC_B_ACTB401_0
(PROTON-GATED ION
CHANNEL)		 6f1v CYTOPLASMIC DYNEIN 1
HEAVY CHAIN 1
(Homo
sapiens) 		4 / 6 ILE f 877
ARG f 914
ILE f 910
GLU f 865
 None
 1.43A 4zzcB-6f1vf:
2.6
4zzcC-6f1vf:
2.5		 4zzcB-6f1vf:
undetectable
4zzcC-6f1vf:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DNU_A_BEZA319_0
(SHKAI2IB)		 6f1v CYTOPLASMIC DYNEIN 1
HEAVY CHAIN 1
(Homo
sapiens) 		4 / 5 GLN f 813
ILE f 816
ILE f 820
TYR f 788
 None
 1.16A 5dnuA-6f1vf:
undetectable		 5dnuA-6f1vf:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DNV_A_BEZA304_0
(SHKAI2IB)		 6f1v CYTOPLASMIC DYNEIN 1
HEAVY CHAIN 1
(Homo
sapiens) 		4 / 5 GLN f 813
ILE f 816
ILE f 820
TYR f 788
 None
 1.13A 5dnvA-6f1vf:
undetectable		 5dnvA-6f1vf:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 6f1v CYTOPLASMIC DYNEIN 1
HEAVY CHAIN 1
(Homo
sapiens) 		4 / 5 ARG f 664
MET f 662
THR f 659
LEU f 658
 None
 1.44A 5x1bJ-6f1vf:
undetectable		 5x1bJ-6f1vf:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_J_CHDJ102_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 6f1v CYTOPLASMIC DYNEIN 1
HEAVY CHAIN 1
(Homo
sapiens) 		4 / 5 ARG f 664
MET f 662
THR f 659
LEU f 658
 None
 1.43A 6nknJ-6f1vf:
undetectable		 6nknJ-6f1vf:
undetectable