SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6f2d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EUP_A_ASDA452_1
(CYTOCHROME P450ERYF)		 6f2d FLAGELLAR
BIOSYNTHETIC PROTEIN
FLIP
FLAGELLAR
BIOSYNTHETIC PROTEIN
FLIQ
FLAGELLAR
BIOSYNTHETIC PROTEIN
FLIR
(Salmonella
enterica) 		4 / 8 ILE F 226
LEU F 222
LEU A 198
LEU G  25
 None
 0.86A 1eupA-6f2dF:
undetectable		 1eupA-6f2dF:
12.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QCA_A_FUAA221_1
(TYPE III
CHLORAMPHENICOL
ACETYLTRANSFERASE)		 6f2d FLAGELLAR
BIOSYNTHETIC PROTEIN
FLIP
FLAGELLAR
BIOSYNTHETIC PROTEIN
FLIQ
(Salmonella
enterica) 		4 / 7 THR A 188
PHE A 193
PHE G  81
LEU A 239
 None
 1.11A 1qcaA-6f2dA:
undetectable		 1qcaA-6f2dA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TZ8_B_DESB128_1
(TRANSTHYRETIN)		 6f2d FLAGELLAR
BIOSYNTHETIC PROTEIN
FLIQ
FLAGELLAR
BIOSYNTHETIC PROTEIN
FLIR
(Salmonella
enterica) 		5 / 11 LEU F 204
LEU F 211
SER F 212
LEU G  29
SER G  36
 None
 1.15A 1tz8A-6f2dF:
undetectable
1tz8B-6f2dF:
undetectable		 1tz8A-6f2dF:
22.22
1tz8B-6f2dF:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TZ8_B_DESB128_1
(TRANSTHYRETIN)		 6f2d FLAGELLAR
BIOSYNTHETIC PROTEIN
FLIQ
FLAGELLAR
BIOSYNTHETIC PROTEIN
FLIR
(Salmonella
enterica) 		5 / 11 LEU G  29
SER G  36
LEU F 204
LEU F 211
SER F 212
 None
 1.13A 1tz8A-6f2dG:
undetectable
1tz8B-6f2dG:
undetectable		 1tz8A-6f2dG:
23.20
1tz8B-6f2dG:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_B_STRB2001_2
(MINERALOCORTICOID
RECEPTOR)		 6f2d FLAGELLAR
BIOSYNTHETIC PROTEIN
FLIP
FLAGELLAR
BIOSYNTHETIC PROTEIN
FLIQ
FLAGELLAR
BIOSYNTHETIC PROTEIN
FLIR
(Salmonella
enterica) 		3 / 3 LEU F 125
LEU A 194
MET G  14
 None
 0.52A 1ya3B-6f2dF:
undetectable		 1ya3B-6f2dF:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BDM_A_TMIA501_1
(CYTOCHROME P450 2B4)		 6f2d FLAGELLAR
BIOSYNTHETIC PROTEIN
FLIR
(Salmonella
enterica) 		4 / 7 LEU F  26
GLY F  85
THR F  87
ILE F 254
 None
 1.04A 2bdmA-6f2dF:
undetectable		 2bdmA-6f2dF:
9.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNH_B_9CRB501_1
(CYTOCHROME P450 2C8)		 6f2d FLAGELLAR
BIOSYNTHETIC PROTEIN
FLIP
FLAGELLAR
BIOSYNTHETIC PROTEIN
FLIR
(Salmonella
enterica) 		5 / 9 ARG A 168
ILE A 169
PRO F  56
ILE F  54
VAL F 151
 None
 1.30A 2nnhB-6f2dA:
undetectable		 2nnhB-6f2dA:
9.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_C_ECNC403_1
(FLAVOHEMOGLOBIN)		 6f2d FLAGELLAR
BIOSYNTHETIC PROTEIN
FLIP
(Salmonella
enterica) 		5 / 9 ILE A 189
THR A 188
PHE A 187
GLN A 184
LEU A  73
 None
 1.25A 4g1bC-6f2dA:
undetectable		 4g1bC-6f2dA:
11.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KM0_B_CP6B201_1
(DIHYDROFOLATE
REDUCTASE)		 6f2d FLAGELLAR
BIOSYNTHETIC PROTEIN
FLIP
FLAGELLAR
BIOSYNTHETIC PROTEIN
FLIR
(Salmonella
enterica) 		5 / 12 ILE F  54
ALA A 154
ILE A 169
THR A 176
ILE F  50
 None
 1.13A 4km0B-6f2dF:
undetectable		 4km0B-6f2dF:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KM2_B_TOPB202_1
(DIHYDROFOLATE
REDUCTASE)		 6f2d FLAGELLAR
BIOSYNTHETIC PROTEIN
FLIP
FLAGELLAR
BIOSYNTHETIC PROTEIN
FLIR
(Salmonella
enterica) 		5 / 12 ILE F  54
ALA A 154
ILE A 169
THR A 176
ILE F  50
 None
 1.09A 4km2B-6f2dF:
undetectable		 4km2B-6f2dF:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADL_B_H4BB600_1
(ENDOTHELIAL NITRIC
OXIDE SYNTHASE)		 6f2d FLAGELLAR
BIOSYNTHETIC PROTEIN
FLIP
(Salmonella
enterica) 		4 / 7 PHE A 183
GLU A 178
SER A 177
VAL A 175
 None
 1.41A 5adlA-6f2dA:
undetectable
5adlB-6f2dA:
undetectable		 5adlA-6f2dA:
11.43
5adlB-6f2dA:
11.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_O_BEZO801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 6f2d FLAGELLAR
BIOSYNTHETIC PROTEIN
FLIP
FLAGELLAR
BIOSYNTHETIC PROTEIN
FLIR
(Salmonella
enterica;
Salmonella
enterica) 		4 / 6 SER F  34
HIS F 143
MET F 134
LEU A 179
 None
 1.06A 5dzka-6f2dF:
undetectable
5dzko-6f2dF:
undetectable		 5dzka-6f2dF:
undetectable
5dzko-6f2dF:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_P_BEZP801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 6f2d FLAGELLAR
BIOSYNTHETIC PROTEIN
FLIP
FLAGELLAR
BIOSYNTHETIC PROTEIN
FLIR
(Salmonella
enterica;
Salmonella
enterica) 		4 / 5 SER F  34
HIS F 143
MET F 134
LEU A 179
 None
 1.01A 5dzkb-6f2dF:
undetectable
5dzkp-6f2dF:
undetectable		 5dzkb-6f2dF:
undetectable
5dzkp-6f2dF:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_P_BEZP801_1
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 6f2d FLAGELLAR
BIOSYNTHETIC PROTEIN
FLIP
FLAGELLAR
BIOSYNTHETIC PROTEIN
FLIR
(Salmonella
enterica;
Salmonella
enterica) 		4 / 6 SER F  34
HIS F 143
MET F 134
LEU A 179
 None
 1.16A 5dzkB-6f2dF:
undetectable
5dzkP-6f2dF:
undetectable		 5dzkB-6f2dF:
undetectable
5dzkP-6f2dF:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_Q_BEZQ801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 6f2d FLAGELLAR
BIOSYNTHETIC PROTEIN
FLIP
FLAGELLAR
BIOSYNTHETIC PROTEIN
FLIR
(Salmonella
enterica;
Salmonella
enterica) 		4 / 5 SER F  34
HIS F 143
MET F 134
LEU A 179
 None
 1.04A 5dzkc-6f2dF:
undetectable
5dzkq-6f2dF:
undetectable		 5dzkc-6f2dF:
undetectable
5dzkq-6f2dF:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_R_BEZR801_1
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 6f2d FLAGELLAR
BIOSYNTHETIC PROTEIN
FLIP
FLAGELLAR
BIOSYNTHETIC PROTEIN
FLIR
(Salmonella
enterica;
Salmonella
enterica) 		4 / 8 SER F  34
HIS F 143
MET F 134
LEU A 179
 None
 1.15A 5dzkd-6f2dF:
undetectable
5dzkr-6f2dF:
undetectable		 5dzkd-6f2dF:
undetectable
5dzkr-6f2dF:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_S_BEZS801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 6f2d FLAGELLAR
BIOSYNTHETIC PROTEIN
FLIP
FLAGELLAR
BIOSYNTHETIC PROTEIN
FLIR
(Salmonella
enterica;
Salmonella
enterica) 		4 / 6 SER F  34
HIS F 143
MET F 134
LEU A 179
 None
 1.03A 5dzke-6f2dF:
undetectable
5dzks-6f2dF:
undetectable		 5dzke-6f2dF:
undetectable
5dzks-6f2dF:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_T_BEZT801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 6f2d FLAGELLAR
BIOSYNTHETIC PROTEIN
FLIP
FLAGELLAR
BIOSYNTHETIC PROTEIN
FLIR
(Salmonella
enterica;
Salmonella
enterica) 		4 / 5 SER F  34
HIS F 143
MET F 134
LEU A 179
 None
 1.07A 5dzkf-6f2dF:
undetectable
5dzkt-6f2dF:
undetectable		 5dzkf-6f2dF:
undetectable
5dzkt-6f2dF:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_T_BEZT801_1
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 6f2d FLAGELLAR
BIOSYNTHETIC PROTEIN
FLIP
FLAGELLAR
BIOSYNTHETIC PROTEIN
FLIR
(Salmonella
enterica;
Salmonella
enterica) 		4 / 8 SER F  34
HIS F 143
MET F 134
LEU A 179
 None
 1.08A 5dzkF-6f2dF:
undetectable
5dzkT-6f2dF:
undetectable		 5dzkF-6f2dF:
undetectable
5dzkT-6f2dF:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_U_BEZU801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 6f2d FLAGELLAR
BIOSYNTHETIC PROTEIN
FLIP
FLAGELLAR
BIOSYNTHETIC PROTEIN
FLIR
(Salmonella
enterica;
Salmonella
enterica) 		4 / 6 SER F  34
HIS F 143
MET F 134
LEU A 179
 None
 1.04A 5dzkg-6f2dF:
undetectable
5dzku-6f2dF:
undetectable		 5dzkg-6f2dF:
undetectable
5dzku-6f2dF:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OTR_A_ACTA402_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 6f2d FLAGELLAR
BIOSYNTHETIC PROTEIN
FLIP
FLAGELLAR
BIOSYNTHETIC PROTEIN
FLIQ
(Salmonella
enterica;
Salmonella
enterica) 		4 / 5 TYR G  76
VAL G  16
PRO A 192
ALA G  13
 None
 1.03A 5otrA-6f2dG:
undetectable		 5otrA-6f2dG:
undetectable