SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6f36'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4007_1
(SERUM ALBUMIN)		 6f36 MITOCHONDRIAL ATP
SYNTHASE SUBUNIT 6
MITOCHONDRIAL ATP
SYNTHASE SUBUNIT
ASA6
(Polytomella
sp.
Pringsheim
198.80) 		4 / 8 LEU M 251
HIS M 252
ASP N 102
LEU N 105
 None
 1.05A 1e7cA-6f36M:
3.1		 1e7cA-6f36M:
9.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G5Y_C_9CRC502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 6f36 MITOCHONDRIAL ATP
SYNTHASE SUBUNIT 6
MITOCHONDRIAL ATP
SYNTHASE SUBUNIT C
(Polytomella
sp.
Pringsheim
198.80) 		5 / 10 LEU M 236
SER M 235
ALA A 108
PHE M 299
ILE M 301
 None
 1.28A 1g5yC-6f36M:
undetectable		 1g5yC-6f36M:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT6_B_DESB128_1
(TRANSTHYRETIN)		 6f36 MITOCHONDRIAL ATP
SYNTHASE SUBUNIT 6
(Polytomella
sp.
Pringsheim
198.80) 		4 / 5 LEU M 167
ALA M 292
LEU M 164
SER M 161
 None
 1.05A 1tt6B-6f36M:
undetectable		 1tt6B-6f36M:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOQ_A_ROFA502_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 6f36 MITOCHONDRIAL ATP
SYNTHASE SUBUNIT 6
MITOCHONDRIAL ATP
SYNTHASE SUBUNIT
ASA6
(Polytomella
sp.
Pringsheim
198.80;
Polytomella
sp.
Pringsheim
198.80) 		3 / 3 ASN M 171
TRP N  85
GLN N  93
 None
 1.24A 1xoqA-6f36M:
undetectable		 1xoqA-6f36M:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_D_SNLD4001_2
(MINERALOCORTICOID
RECEPTOR)		 6f36 MITOCHONDRIAL ATP
SYNTHASE SUBUNIT 6
MITOCHONDRIAL ATP
SYNTHASE SUBUNIT
ASA6
(Polytomella
sp.
Pringsheim
198.80) 		4 / 5 LEU M 259
LEU N 105
CYH M 278
THR M 274
 None
 1.42A 2oaxD-6f36M:
undetectable		 2oaxD-6f36M:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MNE_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 6f36 MITOCHONDRIAL ATP
SYNTHASE SUBUNIT 6
MITOCHONDRIAL ATP
SYNTHASE SUBUNIT
ASA6
(Polytomella
sp.
Pringsheim
198.80) 		5 / 12 ASN M 163
GLY M 166
ARG N  89
LEU M 245
ILE M 159
 None
 1.29A 3mneA-6f36M:
undetectable		 3mneA-6f36M:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MNO_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 6f36 MITOCHONDRIAL ATP
SYNTHASE SUBUNIT 6
MITOCHONDRIAL ATP
SYNTHASE SUBUNIT
ASA6
(Polytomella
sp.
Pringsheim
198.80) 		5 / 12 ASN M 163
GLY M 166
ARG N  89
LEU M 245
ILE M 159
 None
 1.31A 3mnoA-6f36M:
undetectable		 3mnoA-6f36M:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MNO_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 6f36 MITOCHONDRIAL ATP
SYNTHASE SUBUNIT 6
MITOCHONDRIAL ATP
SYNTHASE SUBUNIT
ASA6
(Polytomella
sp.
Pringsheim
198.80) 		5 / 12 ASN M 163
GLY M 166
GLN N 109
LEU M 245
ILE M 159
 None
 1.41A 3mnoA-6f36M:
undetectable		 3mnoA-6f36M:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MNP_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 6f36 MITOCHONDRIAL ATP
SYNTHASE SUBUNIT 6
MITOCHONDRIAL ATP
SYNTHASE SUBUNIT
ASA6
(Polytomella
sp.
Pringsheim
198.80) 		5 / 12 ASN M 163
GLY M 166
ARG N  89
LEU M 245
ILE M 159
 None
 1.28A 3mnpA-6f36M:
undetectable		 3mnpA-6f36M:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_A_ZPCA1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 6f36 MITOCHONDRIAL ATP
SYNTHASE SUBUNIT
ASA6
(Polytomella
sp.
Pringsheim
198.80) 		4 / 7 PHE N 129
TYR N 126
VAL N 125
ILE N 120
 None
 1.11A 4a97E-6f36N:
undetectable		 4a97E-6f36N:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_D_ZPCD1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 6f36 MITOCHONDRIAL ATP
SYNTHASE SUBUNIT
ASA6
(Polytomella
sp.
Pringsheim
198.80) 		4 / 8 PHE N 129
TYR N 126
VAL N 125
ILE N 120
 None
 1.11A 4a97C-6f36N:
undetectable		 4a97C-6f36N:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_E_ZPCE1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 6f36 MITOCHONDRIAL ATP
SYNTHASE SUBUNIT
ASA6
(Polytomella
sp.
Pringsheim
198.80) 		4 / 8 PHE N 129
TYR N 126
VAL N 125
ILE N 120
 None
 1.09A 4a97D-6f36N:
undetectable		 4a97D-6f36N:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_H_ZPCH1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 6f36 MITOCHONDRIAL ATP
SYNTHASE SUBUNIT
ASA6
(Polytomella
sp.
Pringsheim
198.80) 		4 / 8 PHE N 129
TYR N 126
VAL N 125
ILE N 120
 None
 1.06A 4a97G-6f36N:
undetectable		 4a97G-6f36N:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_I_ZPCI1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 6f36 MITOCHONDRIAL ATP
SYNTHASE SUBUNIT
ASA6
(Polytomella
sp.
Pringsheim
198.80) 		4 / 7 PHE N 129
TYR N 126
VAL N 125
ILE N 120
 None
 1.08A 4a97H-6f36N:
undetectable		 4a97H-6f36N:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_J_ZPCJ1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 6f36 MITOCHONDRIAL ATP
SYNTHASE SUBUNIT
ASA6
(Polytomella
sp.
Pringsheim
198.80) 		4 / 8 PHE N 129
TYR N 126
VAL N 125
ILE N 120
 None
 1.08A 4a97I-6f36N:
undetectable		 4a97I-6f36N:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XOO_B_ADNB503_1
(GLYCOSAMINOGLYCAN
XYLOSYLKINASE)		 6f36 MITOCHONDRIAL ATP
SYNTHASE SUBUNIT 6
MITOCHONDRIAL ATP
SYNTHASE SUBUNIT
ASA6
(Polytomella
sp.
Pringsheim
198.80) 		4 / 5 LEU N 108
VAL M 285
GLU M 288
LEU M 251
 None
 1.10A 5xooB-6f36N:
undetectable		 5xooB-6f36N:
22.47