SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6f39'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QVT_A_PRLA311_0
(TRANSCRIPTIONAL
REGULATOR QACR)		 6f39 COMPLEMENT C1R
SUBCOMPONENT
(Homo
sapiens) 		4 / 8 GLU A 179
THR A 182
TYR A 181
ILE A 188
 None
 0.90A 1qvtA-6f39A:
undetectable		 1qvtA-6f39A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VOU_A_ACTA1397_0
(2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE)		 6f39 COMPLEMENT C1R
SUBCOMPONENT
(Homo
sapiens) 		3 / 3 PRO A 199
GLY A 276
TYR A 197
 None
CA  A 303 ( 3.9A)
None
 0.41A 2vouA-6f39A:
undetectable		 2vouA-6f39A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VOU_B_ACTB1391_0
(2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE)		 6f39 COMPLEMENT C1R
SUBCOMPONENT
(Homo
sapiens) 		3 / 3 PRO A 199
GLY A 276
TYR A 197
 None
CA  A 303 ( 3.9A)
None
 0.51A 2vouB-6f39A:
undetectable		 2vouB-6f39A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VOU_C_ACTC1391_0
(2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE)		 6f39 COMPLEMENT C1R
SUBCOMPONENT
(Homo
sapiens) 		3 / 3 PRO A 199
GLY A 276
TYR A 197
 None
CA  A 303 ( 3.9A)
None
 0.51A 2vouC-6f39A:
undetectable		 2vouC-6f39A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM9_A_FVXA603_1
(TRANSPORTER)		 6f39 COMPLEMENT C1R
SUBCOMPONENT
(Homo
sapiens) 		5 / 11 ASP A 226
TYR A 197
GLY A 252
PHE A 223
SER A 278
 CA  A 303 (-3.2A)
None
None
None
CA  A 303 ( 3.8A)
 1.14A 4mm9A-6f39A:
undetectable		 4mm9A-6f39A:
8.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMB_A_SREA603_1
(TRANSPORTER)		 6f39 COMPLEMENT C1R
SUBCOMPONENT
(Homo
sapiens) 		5 / 9 ASP A 226
TYR A 197
GLY A 252
PHE A 223
SER A 278
 CA  A 303 (-3.2A)
None
None
None
CA  A 303 ( 3.8A)
 1.14A 4mmbA-6f39A:
undetectable		 4mmbA-6f39A:
9.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMC_A_29JA603_1
(TRANSPORTER)		 6f39 COMPLEMENT C1R
SUBCOMPONENT
(Homo
sapiens) 		5 / 10 ASP A 226
TYR A 197
GLY A 252
PHE A 223
SER A 278
 CA  A 303 (-3.2A)
None
None
None
CA  A 303 ( 3.8A)
 1.04A 4mmcA-6f39A:
undetectable		 4mmcA-6f39A:
9.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMD_B_29EB603_1
(TRANSPORTER)		 6f39 COMPLEMENT C1R
SUBCOMPONENT
(Homo
sapiens) 		5 / 12 ASP A 226
TYR A 197
GLY A 252
PHE A 223
SER A 278
 CA  A 303 (-3.2A)
None
None
None
CA  A 303 ( 3.8A)
 1.10A 4mmdB-6f39A:
undetectable		 4mmdB-6f39A:
9.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MME_B_29QB603_1
(TRANSPORTER)		 6f39 COMPLEMENT C1R
SUBCOMPONENT
(Homo
sapiens) 		5 / 9 ASP A 226
TYR A 197
GLY A 252
PHE A 223
SER A 278
 CA  A 303 (-3.2A)
None
None
None
CA  A 303 ( 3.8A)
 1.14A 4mmeB-6f39A:
undetectable		 4mmeB-6f39A:
9.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 2)		 6f39 COMPLEMENT C1R
SUBCOMPONENT
(Homo
sapiens) 		3 / 3 PHE A  43
THR A  27
LEU A  48
 None
 0.62A 4qztA-6f39A:
undetectable		 4qztA-6f39A:
undetectable