SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6f4a'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QXY_B_SAMB6735_0
(N-LYSINE
METHYLTRANSFERASE
SETD6
TRANSCRIPTION FACTOR
P65)		 6f4a EXORIBONUCLEASE II,
MITOCHONDRIAL
([Candida]
glabrata) 		5 / 11 ALA A 372
GLY A 373
TYR A 370
ALA A 322
TYR A 326
 None
 1.44A 3qxyB-6f4aA:
undetectable
3qxyQ-6f4aA:
undetectable		 3qxyB-6f4aA:
undetectable
3qxyQ-6f4aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3N_B_MIYB2001_1
(TETX2 PROTEIN)		 6f4a EXORIBONUCLEASE II,
MITOCHONDRIAL
([Candida]
glabrata) 		4 / 8 PHE A 503
HIS A 781
GLY A 501
GLY A 771
 None
 0.74A 3v3nB-6f4aA:
undetectable		 3v3nB-6f4aA:
12.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3N_C_MIYC2001_1
(TETX2 PROTEIN)		 6f4a EXORIBONUCLEASE II,
MITOCHONDRIAL
([Candida]
glabrata) 		4 / 8 PHE A 503
HIS A 781
GLY A 501
GLY A 771
 None
 0.74A 3v3nC-6f4aA:
undetectable		 3v3nC-6f4aA:
12.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTZ_B_LDPB501_1
(CYTOCHROME P450 BM3
VARIANT 8C8)		 6f4a EXORIBONUCLEASE II,
MITOCHONDRIAL
([Candida]
glabrata) 		4 / 6 ALA A 689
ALA A 760
PRO A 752
THR A 759
 None
 1.10A 4dtzB-6f4aA:
undetectable		 4dtzB-6f4aA:
11.88