SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6f71'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_A_CCSA381_0
(ESTROGEN RECEPTOR)		 6f71 GLUTATHIONE
TRANSFERASE
(Trametes
versicolor) 		4 / 5 GLU A 225
ALA A 227
SER A  13
HIS A  19
 None
 1.10A 1errA-6f71A:
undetectable
1errB-6f71A:
undetectable		 1errA-6f71A:
undetectable
1errB-6f71A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P33_A_MTXA351_1
(PTERIDINE REDUCTASE
1)		 6f71 GLUTATHIONE
TRANSFERASE
(Trametes
versicolor) 		5 / 12 PHE A 113
ASP A 165
LEU A 149
LEU A 172
LEU A 121
 None
 1.26A 1p33A-6f71A:
undetectable		 1p33A-6f71A:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WLJ_A_SPMA1303_1
(POTASSIUM CHANNEL)		 6f71 GLUTATHIONE
TRANSFERASE
(Trametes
versicolor) 		3 / 3 ARG A 174
ARG A  20
PRO A  18
 None
 1.07A 2wljA-6f71A:
undetectable		 2wljA-6f71A:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCR_A_CHDA424_0
(FERROCHELATASE,
MITOCHONDRIAL)		 6f71 GLUTATHIONE
TRANSFERASE
(Trametes
versicolor) 		4 / 8 PRO A 101
SER A 102
GLY A 158
PRO A 159
 None
 1.15A 3hcrA-6f71A:
undetectable		 3hcrA-6f71A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBQ_B_URFB400_1
(URIDINE
PHOSPHORYLASE 1)		 6f71 GLUTATHIONE
TRANSFERASE
(Trametes
versicolor) 		4 / 8 ARG A  20
LEU A 121
LEU A 122
ILE A 171
 None
 0.91A 3nbqB-6f71A:
undetectable		 3nbqB-6f71A:
11.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBQ_C_URFC400_1
(URIDINE
PHOSPHORYLASE 1)		 6f71 GLUTATHIONE
TRANSFERASE
(Trametes
versicolor) 		4 / 8 ARG A  20
LEU A 121
LEU A 122
ILE A 171
 None
 0.92A 3nbqC-6f71A:
undetectable		 3nbqC-6f71A:
11.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VLN_A_ASCA904_0
(GLUTATHIONE
S-TRANSFERASE
OMEGA-1)		 6f71 GLUTATHIONE
TRANSFERASE
(Trametes
versicolor) 		5 / 6 PHE A  17
ARG A  20
PRO A  58
GLU A  82
SER A  83
 None
 0.42A 3vlnA-6f71A:
21.4		 3vlnA-6f71A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_G_ACTG306_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 6f71 GLUTATHIONE
TRANSFERASE
(Trametes
versicolor) 		3 / 3 ARG A  22
ARG A 174
ASP A 224
 None
 0.91A 3wipG-6f71A:
undetectable
3wipH-6f71A:
undetectable		 3wipG-6f71A:
undetectable
3wipH-6f71A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7G_A_ACTA514_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 6f71 GLUTATHIONE
TRANSFERASE
(Trametes
versicolor) 		4 / 4 ALA A 164
VAL A 168
ASP A 165
LEU A 149
 None
 0.95A 4e7gA-6f71A:
undetectable		 4e7gA-6f71A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJQ_A_27RA401_1
(DNA POLYMERASE III
SUBUNIT BETA)		 6f71 GLUTATHIONE
TRANSFERASE
(Trametes
versicolor) 		4 / 5 ARG A  54
TYR A  51
PRO A  81
VAL A  85
 None
 1.16A 4mjqA-6f71A:
undetectable		 4mjqA-6f71A:
11.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM4_B_8PRB603_2
(TRANSPORTER)		 6f71 GLUTATHIONE
TRANSFERASE
(Trametes
versicolor) 		3 / 3 SER A  13
MET A  11
ASP A  41
 None
 0.88A 4mm4B-6f71A:
undetectable		 4mm4B-6f71A:
8.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OQR_A_2UOA502_1
(CYP105AS1)		 6f71 GLUTATHIONE
TRANSFERASE
(Trametes
versicolor) 		5 / 9 PRO A 170
VAL A  21
VAL A 228
ALA A  14
VAL A  57
 None
 1.23A 4oqrA-6f71A:
undetectable		 4oqrA-6f71A:
10.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RYA_A_ACTA502_0
(ABC TRANSPORTER
SUBSTRATE BINDING
PROTEIN (SORBITOL))		 6f71 GLUTATHIONE
TRANSFERASE
(Trametes
versicolor) 		4 / 4 LYS A 238
ARG A 235
GLY A 234
ASP A  41
 None
 1.39A 4ryaA-6f71A:
undetectable		 4ryaA-6f71A:
undetectable