SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6f79'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N6C_A_SAMA402_0
(SET
DOMAIN-CONTAINING
PROTEIN 7)		 6f79 -
(-) 		5 / 11 ALA A  70
GLY A 116
GLU A 117
ASN A 112
HIS A  68
 None
 1.48A 1n6cA-6f79A:
undetectable		 1n6cA-6f79A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P93_B_DEXB2999_1
(GLUCOCORTICOID
RECEPTOR)		 6f79 -
(-) 		5 / 12 MET A 240
ASN A 244
MET A  78
LEU A  85
ILE A 210
 None
 1.27A 1p93B-6f79A:
undetectable		 1p93B-6f79A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BTE_A_LEUA1894_0
(AMINOACYL-TRNA
SYNTHETASE)		 6f79 -
(-) 		4 / 8 ASP A 260
TYR A 149
HIS A  69
HIS A  68
 0X9  A 407 (-4.3A)
None
ZN  A 401 ( 3.1A)
None
 1.25A 2bteA-6f79A:
undetectable		 2bteA-6f79A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BTE_D_LEUD1893_0
(AMINOACYL-TRNA
SYNTHETASE)		 6f79 -
(-) 		4 / 8 ASP A 260
TYR A 149
HIS A  69
HIS A  68
 0X9  A 407 (-4.3A)
None
ZN  A 401 ( 3.1A)
None
 1.21A 2bteD-6f79A:
1.4		 2bteD-6f79A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BYT_A_LEUA1301_0
(LEUCYL-TRNA
SYNTHETASE)		 6f79 -
(-) 		4 / 7 ASP A 260
TYR A 149
HIS A  69
HIS A  68
 0X9  A 407 (-4.3A)
None
ZN  A 401 ( 3.1A)
None
 1.27A 2bytA-6f79A:
undetectable		 2bytA-6f79A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BYT_D_LEUD1601_0
(LEUCYL-TRNA
SYNTHETASE)		 6f79 -
(-) 		4 / 7 ASP A 260
TYR A 149
HIS A  69
HIS A  68
 0X9  A 407 (-4.3A)
None
ZN  A 401 ( 3.1A)
None
 1.26A 2bytD-6f79A:
undetectable		 2bytD-6f79A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_B_NCAB1246_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 6f79 -
(-) 		4 / 7 GLY A 286
SER A 207
PHE A 287
GLU A 277
 None
None
None
0X9  A 407 (-3.2A)
 1.02A 2c8aB-6f79A:
undetectable		 2c8aB-6f79A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_D_NCAD1247_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 6f79 -
(-) 		4 / 7 GLY A 286
SER A 207
PHE A 287
GLU A 277
 None
None
None
0X9  A 407 (-3.2A)
 1.09A 2c8aD-6f79A:
undetectable		 2c8aD-6f79A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBL_A_CAMA517_0
(CYTOCHROME P450-CAM)		 6f79 -
(-) 		4 / 7 PHE A   2
LEU A  67
VAL A  76
THR A  75
 None
 0.92A 2qblA-6f79A:
undetectable		 2qblA-6f79A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0G_A_LEUA1887_0
(AMINOACYL-TRNA
SYNTHETASE)		 6f79 -
(-) 		4 / 8 ASP A 260
TYR A 149
HIS A  69
HIS A  68
 0X9  A 407 (-4.3A)
None
ZN  A 401 ( 3.1A)
None
 1.24A 2v0gA-6f79A:
1.7		 2v0gA-6f79A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_A_HSMA1162_1
(ALLERGEN ARG R 1)		 6f79 -
(-) 		4 / 4 GLU A 277
ASP A 144
HIS A  69
GLU A  72
 0X9  A 407 (-3.2A)
0X9  A 407 ( 4.9A)
ZN  A 401 ( 3.1A)
ZN  A 401 ( 1.9A)
 1.48A 2x45A-6f79A:
undetectable		 2x45A-6f79A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_B_HSMB1162_1
(ALLERGEN ARG R 1)		 6f79 -
(-) 		3 / 3 GLU A 277
HIS A  69
GLU A  72
 0X9  A 407 (-3.2A)
ZN  A 401 ( 3.1A)
ZN  A 401 ( 1.9A)
 0.77A 2x45B-6f79A:
undetectable		 2x45B-6f79A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_C_HSMC1162_1
(ALLERGEN ARG R 1)		 6f79 -
(-) 		3 / 3 GLU A 277
HIS A  69
GLU A  72
 0X9  A 407 (-3.2A)
ZN  A 401 ( 3.1A)
ZN  A 401 ( 1.9A)
 0.80A 2x45C-6f79A:
undetectable		 2x45C-6f79A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_B_SALB404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 6f79 -
(-) 		4 / 7 ASN A 110
PRO A 113
ARG A 132
ALA A  70
 None
 1.13A 3twpB-6f79A:
undetectable		 3twpB-6f79A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_C_SALC404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 6f79 -
(-) 		4 / 7 ASN A 110
PRO A 113
ARG A 132
ALA A  70
 None
 1.13A 3twpC-6f79A:
undetectable		 3twpC-6f79A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9K_A_CAMA424_0
(CYTOCHROME P450)		 6f79 -
(-) 		5 / 9 TYR A 149
THR A 179
THR A 202
LEU A 145
VAL A 108
 None
 1.41A 4c9kA-6f79A:
undetectable		 4c9kA-6f79A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FJP_A_NPSA711_1
(LACTOTRANSFERRIN)		 6f79 -
(-) 		4 / 6 GLY A 115
PRO A 113
ASN A 112
GLY A  41
 None
 0.82A 4fjpA-6f79A:
undetectable		 4fjpA-6f79A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M5M_A_DX4A401_0
(2-AMINO-4-HYDROXY-6-
HYDROXYMETHYLDIHYDRO
PTERIDINE
PYROPHOSPHOKINASE)		 6f79 -
(-) 		4 / 8 GLY A 170
THR A 179
ASN A 148
ARG A 171
 None
 0.95A 4m5mA-6f79A:
undetectable		 4m5mA-6f79A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R82_A_ACTA205_0
(OXIDOREDUCTASE)		 6f79 -
(-) 		4 / 5 SER A  38
GLY A  41
ARG A  42
GLU A  40
 None
 1.28A 4r82A-6f79A:
undetectable
4r82B-6f79A:
undetectable		 4r82A-6f79A:
undetectable
4r82B-6f79A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_I_Z80I401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 6f79 -
(-) 		4 / 9 PHE A 174
ASN A 146
ASP A 263
TRP A 264
 None
0X9  A 407 (-3.9A)
None
SO4  A 406 (-3.8A)
 1.02A 5lg3I-6f79A:
undetectable		 5lg3I-6f79A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZV2_A_LEVA801_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1)		 6f79 -
(-) 		3 / 3 LYS A 302
LEU A  99
ASP A  93
 None
 0.75A 5zv2A-6f79A:
undetectable		 5zv2A-6f79A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BEC_C_RBTC601_1
(SCAFFOLD PROTEIN D13)		 6f79 -
(-) 		5 / 12 PRO A 213
VAL A 308
PHE A 185
PHE A 274
ILE A 201
 None
 1.19A 6becA-6f79A:
undetectable
6becB-6f79A:
undetectable
6becC-6f79A:
undetectable		 6becA-6f79A:
undetectable
6becB-6f79A:
undetectable
6becC-6f79A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_B_ZOLB401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 6f79 -
(-) 		4 / 6 ASP A 260
ASP A 263
ARG A 147
GLN A 211
 0X9  A 407 (-4.3A)
None
0X9  A 407 (-2.9A)
0X9  A 407 (-3.0A)
 1.39A 6g31B-6f79A:
undetectable		 6g31B-6f79A:
undetectable