SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6f7s'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HZE_A_RBFA98_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 6f7s SERRATE RNA EFFECTOR
MOLECULE
HOMOLOG,SERRATE RNA
EFFECTOR MOLECULE
HOMOLOG
(Homo
sapiens) 		5 / 9 LEU C 612
ASP C 609
LEU C 608
ILE C 515
ILE C 506
 None
 1.30A 1hzeA-6f7sC:
undetectable
1hzeB-6f7sC:
undetectable		 1hzeA-6f7sC:
16.33
1hzeB-6f7sC:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HZE_B_RBFB99_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 6f7s SERRATE RNA EFFECTOR
MOLECULE
HOMOLOG,SERRATE RNA
EFFECTOR MOLECULE
HOMOLOG
(Homo
sapiens) 		5 / 9 ILE C 506
LEU C 612
ASP C 609
LEU C 608
ILE C 515
 None
 1.30A 1hzeA-6f7sC:
undetectable
1hzeB-6f7sC:
undetectable		 1hzeA-6f7sC:
16.33
1hzeB-6f7sC:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I18_A_RBFA98_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 6f7s SERRATE RNA EFFECTOR
MOLECULE
HOMOLOG,SERRATE RNA
EFFECTOR MOLECULE
HOMOLOG
(Homo
sapiens) 		5 / 10 LEU C 612
ASP C 609
LEU C 608
ILE C 515
ILE C 506
 None
 1.35A 1i18A-6f7sC:
undetectable
1i18B-6f7sC:
undetectable		 1i18A-6f7sC:
16.33
1i18B-6f7sC:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I18_B_RBFB99_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 6f7s SERRATE RNA EFFECTOR
MOLECULE
HOMOLOG,SERRATE RNA
EFFECTOR MOLECULE
HOMOLOG
(Homo
sapiens) 		5 / 10 ILE C 506
LEU C 612
ASP C 609
LEU C 608
ILE C 515
 None
 1.33A 1i18A-6f7sC:
undetectable
1i18B-6f7sC:
undetectable		 1i18A-6f7sC:
16.33
1i18B-6f7sC:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_F_TFPF211_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 6f7s SERRATE RNA EFFECTOR
MOLECULE
HOMOLOG,SERRATE RNA
EFFECTOR MOLECULE
HOMOLOG
(Homo
sapiens) 		4 / 7 LEU C 439
PHE C 446
LEU C 491
PHE C 468
 None
 0.96A 1wrlE-6f7sC:
undetectable
1wrlF-6f7sC:
undetectable		 1wrlE-6f7sC:
20.45
1wrlF-6f7sC:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YFB_A_ACTA501_0
(METHYL-ACCEPTING
CHEMOTAXIS
TRANSDUCER)		 6f7s SERRATE RNA EFFECTOR
MOLECULE
HOMOLOG,SERRATE RNA
EFFECTOR MOLECULE
HOMOLOG
(Homo
sapiens) 		4 / 7 ASP C 609
ARG C 645
ILE C 520
TYR C 624
 None
 1.06A 2yfbA-6f7sC:
undetectable		 2yfbA-6f7sC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DQF_A_LCRA612_1
(SERUM ALBUMIN)		 6f7s SERRATE RNA EFFECTOR
MOLECULE
HOMOLOG,SERRATE RNA
EFFECTOR MOLECULE
HOMOLOG
(Homo
sapiens) 		5 / 9 LEU C 615
ASP C 519
LEU C 522
LEU C 526
LEU C 672
 None
 0.88A 5dqfA-6f7sC:
undetectable		 5dqfA-6f7sC:
7.80