SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6f8l'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MUI_B_AB1B100_1
(PROTEASE)		 6f8l -
(-) 		5 / 10 ASP G 401
GLY G 403
ALA G 404
VAL G 429
GLY G 425
 None
 0.90A 1muiA-6f8lG:
undetectable		 1muiA-6f8lG:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AB2_B_SNLB503_2
(MINERALOCORTICOID
RECEPTOR)		 6f8l -
(-) 		4 / 5 LEU G 453
LEU G 428
LEU G 408
LEU G 406
 None
 1.05A 2ab2B-6f8lG:
undetectable		 2ab2B-6f8lG:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q1E_C_T44C128_1
(5-HYDROXYISOURATE
HYDROLASE)		 6f8l -
(-) 		4 / 6 LEU G 343
LEU G 345
LEU G 365
LEU G 369
 None
 1.02A 3q1eA-6f8lG:
undetectable
3q1eC-6f8lG:
undetectable		 3q1eA-6f8lG:
undetectable
3q1eC-6f8lG:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q1E_C_T44C128_1
(5-HYDROXYISOURATE
HYDROLASE)		 6f8l -
(-) 		4 / 6 LEU G 365
LEU G 369
LEU G 343
LEU G 345
 None
 0.96A 3q1eA-6f8lG:
undetectable
3q1eC-6f8lG:
undetectable		 3q1eA-6f8lG:
undetectable
3q1eC-6f8lG:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O0W_A_ADNA501_1
(AURORA KINASE A)		 6f8l -
(-) 		5 / 6 LEU G 365
GLY G 337
VAL G 351
ALA G 354
LEU G 380
 None
 1.31A 4o0wA-6f8lG:
undetectable		 4o0wA-6f8lG:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OK1_A_198A1001_2
(ANDROGEN RECEPTOR)		 6f8l -
(-) 		4 / 8 LEU G 439
ASN G 437
LEU G 412
ILE G 467
 None
 1.01A 4ok1A-6f8lG:
undetectable		 4ok1A-6f8lG:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_H_CHDH401_0
(BILE SALT HYDROLASE)		 6f8l -
(-) 		5 / 10 ILE G 438
LEU G 441
LEU G 448
ALA G 447
LEU G 412
 None
 1.14A 5y7pH-6f8lG:
undetectable		 5y7pH-6f8lG:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6N_A_SREA508_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 6f8l -
(-) 		5 / 10 ILE G 467
VAL G 444
ALA G 447
LEU G 431
LEU G 430
 None
 1.02A 6f6nA-6f8lG:
undetectable
6f6nB-6f8lG:
undetectable		 6f6nA-6f8lG:
undetectable
6f6nB-6f8lG:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA824_0
(GEPHYRIN)		 6f8l -
(-) 		4 / 4 LEU G 388
ASP G 434
PRO G 435
ARG G 436
 None
 0.73A 6fgdA-6f8lG:
undetectable		 6fgdA-6f8lG:
undetectable