SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6f9c'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K0B_B_SAMB504_0
(S-ADENOSYLMETHIONINE
SYNTHASE)
6f9c GLYCOPROTEIN
(Rift
Valley
fever
phlebovirus)
4 / 8 ASP A 370
LEU A 368
ASN A 366
ILE A 442
None
0.84A 4k0bA-6f9cA:
undetectable
4k0bA-6f9cA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L7I_B_SAMB501_0
(S-ADENOSYLMETHIONINE
SYNTHASE)
6f9c GLYCOPROTEIN
(Rift
Valley
fever
phlebovirus)
4 / 8 ASP A 370
LEU A 368
ASN A 366
ILE A 442
None
0.87A 4l7iA-6f9cA:
undetectable
4l7iA-6f9cA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKW_A_198A1001_1
(ANDROGEN RECEPTOR)
6f9c GLYCOPROTEIN
(Rift
Valley
fever
phlebovirus)
5 / 12 LEU A 302
GLY A 458
GLN A 300
ILE A 445
VAL A 447
None
1.26A 4okwA-6f9cA:
undetectable
4okwA-6f9cA:
16.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UYM_A_VORA590_1
(14-ALPHA STEROL
DEMETHYLASE)
6f9c GLYCOPROTEIN
(Rift
Valley
fever
phlebovirus)
4 / 7 ALA A 257
SER A 296
ILE A 169
LEU A 212
None
1.07A 4uymA-6f9cA:
undetectable
4uymA-6f9cA:
10.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NY7_A_NCAA303_0
(AMIDASE)
6f9c GLYCOPROTEIN
(Rift
Valley
fever
phlebovirus)
4 / 6 ARG A 161
GLY A 163
PRO A 162
GLU A 214
None
0.85A 5ny7A-6f9cA:
undetectable
5ny7A-6f9cA:
undetectable