SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6f9g'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DMI_A_BHSA1610_1 (NITRIC OXIDE SYNTHASE)	6f9g	METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPU (Pseudomonas putida)	4 / 8	VAL A 306 ALA A 267 TRP A 304 PHE A 73	None	0.95A	1dmiA-6f9gA: undetectable 1dmiB-6f9gA: undetectable	1dmiA-6f9gA: 12.16 1dmiB-6f9gA: 12.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1S3Z_B_RIOB501_0 (AMINOGLYCOSIDE 6'-N-ACETYLTRANSFERA SE)	6f9g	METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPU (Pseudomonas putida)	4 / 8	TYR A 152 VAL A 211 TRP A 186 GLU A 164	PUT A 401 ( 3.5A) None PUT A 401 (-3.5A) None	1.30A	1s3zA-6f9gA: undetectable 1s3zB-6f9gA: undetectable	1s3zA-6f9gA: undetectable 1s3zB-6f9gA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2NV4_B_SAMB202_0 (UPF0066 PROTEIN AF_0241)	6f9g	METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPU (Pseudomonas putida)	5 / 12	GLN A 191 TYR A 120 PRO A 219 GLY A 231 LEU A 187	None PUT A 401 (-4.2A) None None None	1.35A	2nv4B-6f9gA: undetectable	2nv4B-6f9gA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2NYU_B_SAMB201_0 (PUTATIVE RIBOSOMAL RNA METHYLTRANSFERASE 2)	6f9g	METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPU (Pseudomonas putida)	5 / 12	SER A 109 ALA A 84 GLY A 82 LEU A 220 LEU A 98	None	1.02A	2nyuB-6f9gA: undetectable	2nyuB-6f9gA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G2O_A_SAMA500_0 (PCZA361.24)	6f9g	METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPU (Pseudomonas putida)	5 / 12	ALA A 267 GLY A 268 LEU A 242 LEU A 265 GLY A 235	None	1.05A	3g2oA-6f9gA: undetectable	3g2oA-6f9gA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G2O_B_SAMB600_0 (PCZA361.24)	6f9g	METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPU (Pseudomonas putida)	5 / 12	ALA A 267 GLY A 268 LEU A 242 LEU A 265 GLY A 235	None	1.08A	3g2oB-6f9gA: undetectable	3g2oB-6f9gA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3Q70_A_RITA2001_2 (CANDIDAPEPSIN-2)	6f9g	METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPU (Pseudomonas putida)	4 / 6	THR A 188 SER A 215 TYR A 202 ASP A 173	None PUT A 401 ( 4.2A) None None	1.05A	3q70A-6f9gA: undetectable	3q70A-6f9gA: 11.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ZBR_A_NPSA602_1 (SERUM ALBUMIN)	6f9g	METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPU (Pseudomonas putida)	5 / 12	LEU A 119 PHE A 149 LEU A 102 GLY A 142 SER A 109	None	1.36A	4zbrA-6f9gA: undetectable	4zbrA-6f9gA: 7.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5B2Q_A_ACTA1728_0 (CRISPR-ASSOCIATED ENDONUCLEASE CAS9)	6f9g	METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPU (Pseudomonas putida)	3 / 3	ASN A 269 SER A 258 ARG A 290	None	0.84A	5b2qA-6f9gA: undetectable	5b2qA-6f9gA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5M54_E_TA1E502_1 (TUBULIN BETA-2B CHAIN)	6f9g	METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPU (Pseudomonas putida)	5 / 12	ASP A 129 PHE A 83 ARG A 104 GLY A 142 LEU A 151	None	0.99A	5m54E-6f9gA: undetectable	5m54E-6f9gA: 11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZGB_B_PQNB844_1 (PSAB)	6f9g	METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPU (Pseudomonas putida)	5 / 9	ILE A 117 ARG A 107 ALA A 111 LEU A 110 ALA A 106	None	1.29A	5zgbB-6f9gA: undetectable	5zgbB-6f9gA: 21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZGH_B_PQNB843_1 (PSAB)	6f9g	METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPU (Pseudomonas putida)	5 / 9	ILE A 117 ARG A 107 ALA A 111 LEU A 110 ALA A 106	None	1.20A	5zghB-6f9gA: 1.0	5zghB-6f9gA: 21.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6FU4_A_HSMA401_1 (PROBABLE CHEMOTAXIS TRANSDUCER)	6f9g	METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPU (Pseudomonas putida)	7 / 9	TYR A 120 TYR A 152 GLU A 164 TRP A 186 TYR A 202 ASP A 204 ASP A 233	PUT A 401 (-4.2A) PUT A 401 ( 3.5A) None PUT A 401 (-3.5A) None PUT A 401 (-2.7A) PUT A 401 (-2.9A)	0.54A	6fu4A-6f9gA: 37.0	6fu4A-6f9gA: 68.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6FU4_B_HSMB401_1 (PROBABLE CHEMOTAXIS TRANSDUCER)	6f9g	METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPU (Pseudomonas putida)	7 / 9	TYR A 120 TYR A 152 GLU A 164 TRP A 186 TYR A 202 ASP A 204 ASP A 233	PUT A 401 (-4.2A) PUT A 401 ( 3.5A) None PUT A 401 (-3.5A) None PUT A 401 (-2.7A) PUT A 401 (-2.9A)	0.48A	6fu4B-6f9gA: 37.2	6fu4B-6f9gA: 68.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6FU4_C_HSMC401_1 (PROBABLE CHEMOTAXIS TRANSDUCER)	6f9g	METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPU (Pseudomonas putida)	7 / 9	TYR A 120 TYR A 152 GLU A 164 TRP A 186 TYR A 202 ASP A 204 ASP A 233	PUT A 401 (-4.2A) PUT A 401 ( 3.5A) None PUT A 401 (-3.5A) None PUT A 401 (-2.7A) PUT A 401 (-2.9A)	0.55A	6fu4C-6f9gA: 37.1	6fu4C-6f9gA: 68.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6FU4_D_HSMD401_1 (PROBABLE CHEMOTAXIS TRANSDUCER)	6f9g	METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPU (Pseudomonas putida)	7 / 9	TYR A 120 TYR A 152 GLU A 164 TRP A 186 TYR A 202 ASP A 204 ASP A 233	PUT A 401 (-4.2A) PUT A 401 ( 3.5A) None PUT A 401 (-3.5A) None PUT A 401 (-2.7A) PUT A 401 (-2.9A)	0.49A	6fu4D-6f9gA: 36.8	6fu4D-6f9gA: 68.75

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1DMI_A_BHSA1610_1","NITRIC OXIDE SYNTHASE;NITRIC OXIDE SYNTHASE","6f9g","METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPU","Pseudomonas putida",4,"VAL A 306;ALA A 267;TRP A 304;PHE A  73","None","0.95A","1dmiA-6f9gA:undetectable;1dmiB-6f9gA:undetectable","1dmiA-6f9gA:12.16;1dmiB-6f9gA:12.16"],["1S3Z_B_RIOB501_0","AMINOGLYCOSIDE 6'-N-ACETYLTRANSFERASE","6f9g","METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPU","Pseudomonas putida",4,"TYR A 152;VAL A 211;TRP A 186;GLU A 164","PUT A 401 ( 3.5A);None;PUT A 401 (-3.5A);None","1.30A","1s3zA-6f9gA:undetectable;1s3zB-6f9gA:undetectable","1s3zA-6f9gA:undetectable;1s3zB-6f9gA:undetectable"],["2NV4_B_SAMB202_0","UPF0066 PROTEIN AF_0241","6f9g","METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPU","Pseudomonas putida",5,"GLN A 191;TYR A 120;PRO A 219;GLY A 231;LEU A 187","None;PUT A 401 (-4.2A);None;None;None","1.35A","2nv4B-6f9gA:undetectable","2nv4B-6f9gA:undetectable"],["2NYU_B_SAMB201_0","PUTATIVE RIBOSOMAL RNA METHYLTRANSFERASE 2","6f9g","METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPU","Pseudomonas putida",5,"SER A 109;ALA A  84;GLY A  82;LEU A 220;LEU A  98","None","1.02A","2nyuB-6f9gA:undetectable","2nyuB-6f9gA:undetectable"],["3G2O_A_SAMA500_0","PCZA361.24","6f9g","METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPU","Pseudomonas putida",5,"ALA A 267;GLY A 268;LEU A 242;LEU A 265;GLY A 235","None","1.05A","3g2oA-6f9gA:undetectable","3g2oA-6f9gA:undetectable"],["3G2O_B_SAMB600_0","PCZA361.24","6f9g","METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPU","Pseudomonas putida",5,"ALA A 267;GLY A 268;LEU A 242;LEU A 265;GLY A 235","None","1.08A","3g2oB-6f9gA:undetectable","3g2oB-6f9gA:undetectable"],["3Q70_A_RITA2001_2","CANDIDAPEPSIN-2","6f9g","METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPU","Pseudomonas putida",4,"THR A 188;SER A 215;TYR A 202;ASP A 173","None;PUT A 401 ( 4.2A);None;None","1.05A","3q70A-6f9gA:undetectable","3q70A-6f9gA:11.68"],["4ZBR_A_NPSA602_1","SERUM ALBUMIN","6f9g","METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPU","Pseudomonas putida",5,"LEU A 119;PHE A 149;LEU A 102;GLY A 142;SER A 109","None","1.36A","4zbrA-6f9gA:undetectable","4zbrA-6f9gA:7.20"],["5B2Q_A_ACTA1728_0","CRISPR-ASSOCIATED ENDONUCLEASE CAS9","6f9g","METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPU","Pseudomonas putida",3,"ASN A 269;SER A 258;ARG A 290","None","0.84A","5b2qA-6f9gA:undetectable","5b2qA-6f9gA:undetectable"],["5M54_E_TA1E502_1","TUBULIN BETA-2B CHAIN","6f9g","METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPU","Pseudomonas putida",5,"ASP A 129;PHE A  83;ARG A 104;GLY A 142;LEU A 151","None","0.99A","5m54E-6f9gA:undetectable","5m54E-6f9gA:11.03"],["5ZGB_B_PQNB844_1","PSAB","6f9g","METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPU","Pseudomonas putida",5,"ILE A 117;ARG A 107;ALA A 111;LEU A 110;ALA A 106","None","1.29A","5zgbB-6f9gA:undetectable","5zgbB-6f9gA:21.95"],["5ZGH_B_PQNB843_1","PSAB","6f9g","METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPU","Pseudomonas putida",5,"ILE A 117;ARG A 107;ALA A 111;LEU A 110;ALA A 106","None","1.20A","5zghB-6f9gA:1.0","5zghB-6f9gA:21.95"],["6FU4_A_HSMA401_1","PROBABLE CHEMOTAXIS TRANSDUCER","6f9g","METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPU","Pseudomonas putida",7,"TYR A 120;TYR A 152;GLU A 164;TRP A 186;TYR A 202;ASP A 204;ASP A 233","PUT A 401 (-4.2A);PUT A 401 ( 3.5A);None;PUT A 401 (-3.5A);None;PUT A 401 (-2.7A);PUT A 401 (-2.9A)","0.54A","6fu4A-6f9gA:37.0","6fu4A-6f9gA:68.75"],["6FU4_B_HSMB401_1","PROBABLE CHEMOTAXIS TRANSDUCER","6f9g","METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPU","Pseudomonas putida",7,"TYR A 120;TYR A 152;GLU A 164;TRP A 186;TYR A 202;ASP A 204;ASP A 233","PUT A 401 (-4.2A);PUT A 401 ( 3.5A);None;PUT A 401 (-3.5A);None;PUT A 401 (-2.7A);PUT A 401 (-2.9A)","0.48A","6fu4B-6f9gA:37.2","6fu4B-6f9gA:68.75"],["6FU4_C_HSMC401_1","PROBABLE CHEMOTAXIS TRANSDUCER","6f9g","METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPU","Pseudomonas putida",7,"TYR A 120;TYR A 152;GLU A 164;TRP A 186;TYR A 202;ASP A 204;ASP A 233","PUT A 401 (-4.2A);PUT A 401 ( 3.5A);None;PUT A 401 (-3.5A);None;PUT A 401 (-2.7A);PUT A 401 (-2.9A)","0.55A","6fu4C-6f9gA:37.1","6fu4C-6f9gA:68.75"],["6FU4_D_HSMD401_1","PROBABLE CHEMOTAXIS TRANSDUCER","6f9g","METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPU","Pseudomonas putida",7,"TYR A 120;TYR A 152;GLU A 164;TRP A 186;TYR A 202;ASP A 204;ASP A 233","PUT A 401 (-4.2A);PUT A 401 ( 3.5A);None;PUT A 401 (-3.5A);None;PUT A 401 (-2.7A);PUT A 401 (-2.9A)","0.49A","6fu4D-6f9gA:36.8","6fu4D-6f9gA:68.75"]]