SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6f9m'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JFF_B_TA1B601_1
(TUBULIN BETA CHAIN)		 6f9m SERINE PROTEASE
(Planococcus
plakortidis) 		5 / 12 VAL A 150
LEU A 306
SER A 152
LEU A 304
THR A 289
 None
 1.22A 1jffB-6f9mA:
undetectable		 1jffB-6f9mA:
10.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JNO_A_DVAA6_0
(GRAMICIDIN A)		 6f9m SERINE PROTEASE
(Planococcus
plakortidis) 		3 / 3 ALA A  96
VAL A 107
TRP A  34
 NA  A 402 ( 4.7A)
None
None
 0.85A 1jnoA-6f9mA:
undetectable		 1jnoA-6f9mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JNO_B_DVAB6_0
(GRAMICIDIN A)		 6f9m SERINE PROTEASE
(Planococcus
plakortidis) 		3 / 3 ALA A  96
VAL A 107
TRP A  34
 NA  A 402 ( 4.7A)
None
None
 0.85A 1jnoB-6f9mA:
undetectable		 1jnoB-6f9mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO3_A_DVAA6_0
(GRAMICIDIN B)		 6f9m SERINE PROTEASE
(Planococcus
plakortidis) 		3 / 3 ALA A  96
VAL A 107
TRP A  34
 NA  A 402 ( 4.7A)
None
None
 0.69A 1jo3A-6f9mA:
undetectable		 1jo3A-6f9mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO3_B_DVAB6_0
(GRAMICIDIN B)		 6f9m SERINE PROTEASE
(Planococcus
plakortidis) 		3 / 3 ALA A  96
VAL A 107
TRP A  34
 NA  A 402 ( 4.7A)
None
None
 0.69A 1jo3B-6f9mA:
undetectable		 1jo3B-6f9mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO4_A_DVAA6_0
(GRAMICIDIN C)		 6f9m SERINE PROTEASE
(Planococcus
plakortidis) 		3 / 3 ALA A  96
VAL A 107
TRP A  34
 NA  A 402 ( 4.7A)
None
None
 0.88A 1jo4A-6f9mA:
undetectable		 1jo4A-6f9mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO4_B_DVAB6_0
(GRAMICIDIN C)		 6f9m SERINE PROTEASE
(Planococcus
plakortidis) 		3 / 3 ALA A  96
VAL A 107
TRP A  34
 NA  A 402 ( 4.7A)
None
None
 0.88A 1jo4B-6f9mA:
undetectable		 1jo4B-6f9mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LWF_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 6f9m SERINE PROTEASE
(Planococcus
plakortidis) 		5 / 9 LEU A 304
VAL A 207
VAL A 210
GLY A 208
LEU A 285
 None
 1.42A 1lwfA-6f9mA:
1.0		 1lwfA-6f9mA:
9.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAG_A_DVAA6_0
(GRAMICIDIN A)		 6f9m SERINE PROTEASE
(Planococcus
plakortidis) 		3 / 3 ALA A  96
VAL A 107
TRP A  34
 NA  A 402 ( 4.7A)
None
None
 0.94A 1magA-6f9mA:
undetectable		 1magA-6f9mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAG_B_DVAB6_0
(GRAMICIDIN A)		 6f9m SERINE PROTEASE
(Planococcus
plakortidis) 		3 / 3 ALA A  96
VAL A 107
TRP A  34
 NA  A 402 ( 4.7A)
None
None
 0.94A 1magB-6f9mA:
undetectable		 1magB-6f9mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_A_DVAA6_0
(GRAMICIDIN A)		 6f9m SERINE PROTEASE
(Planococcus
plakortidis) 		3 / 3 ALA A  96
VAL A 107
TRP A  34
 NA  A 402 ( 4.7A)
None
None
 0.81A 1ng8A-6f9mA:
undetectable		 1ng8A-6f9mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_B_DVAB6_0
(GRAMICIDIN A)		 6f9m SERINE PROTEASE
(Planococcus
plakortidis) 		3 / 3 ALA A  96
VAL A 107
TRP A  34
 NA  A 402 ( 4.7A)
None
None
 0.81A 1ng8B-6f9mA:
undetectable		 1ng8B-6f9mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRM_A_DVAA6_0
(GRAMICIDIN A)		 6f9m SERINE PROTEASE
(Planococcus
plakortidis) 		3 / 3 ALA A  96
VAL A 107
TRP A  34
 NA  A 402 ( 4.7A)
None
None
 0.90A 1nrmA-6f9mA:
undetectable		 1nrmA-6f9mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRM_B_DVAB6_0
(GRAMICIDIN A)		 6f9m SERINE PROTEASE
(Planococcus
plakortidis) 		3 / 3 ALA A  96
VAL A 107
TRP A  34
 NA  A 402 ( 4.7A)
None
None
 0.90A 1nrmB-6f9mA:
undetectable		 1nrmB-6f9mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRU_A_DVAA6_0
(GRAMICIDIN A)		 6f9m SERINE PROTEASE
(Planococcus
plakortidis) 		3 / 3 ALA A  96
VAL A 107
TRP A  34
 NA  A 402 ( 4.7A)
None
None
 0.89A 1nruA-6f9mA:
undetectable		 1nruA-6f9mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRU_B_DVAB6_0
(GRAMICIDIN A)		 6f9m SERINE PROTEASE
(Planococcus
plakortidis) 		3 / 3 ALA A  96
VAL A 107
TRP A  34
 NA  A 402 ( 4.7A)
None
None
 0.89A 1nruB-6f9mA:
undetectable		 1nruB-6f9mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OXR_A_AINA141_1
(PHOSPHOLIPASE A2
ISOFORM 3)		 6f9m SERINE PROTEASE
(Planococcus
plakortidis) 		4 / 4 LEU A 247
GLY A  85
ASP A  49
TYR A   9
 None
 1.17A 1oxrA-6f9mA:
undetectable		 1oxrA-6f9mA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_H_TACH4888_1
(ELONGATION FACTOR
EF-TU)		 6f9m SERINE PROTEASE
(Planococcus
plakortidis) 		4 / 7 SER A 152
VAL A 150
LEU A 306
THR A  93
 None
 1.05A 2hdnF-6f9mA:
undetectable
2hdnG-6f9mA:
undetectable
2hdnH-6f9mA:
undetectable		 2hdnF-6f9mA:
13.92
2hdnG-6f9mA:
22.78
2hdnH-6f9mA:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HXF_B_TA1B601_1
(TUBULIN BETA CHAIN)		 6f9m SERINE PROTEASE
(Planococcus
plakortidis) 		5 / 12 VAL A 150
LEU A 306
SER A 152
LEU A 304
THR A 289
 None
 1.22A 2hxfB-6f9mA:
undetectable		 2hxfB-6f9mA:
10.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HXH_B_TA1B601_1
(TUBULIN BETA CHAIN)		 6f9m SERINE PROTEASE
(Planococcus
plakortidis) 		5 / 12 VAL A 150
LEU A 306
SER A 152
LEU A 304
THR A 289
 None
 1.22A 2hxhB-6f9mA:
undetectable		 2hxhB-6f9mA:
10.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P4N_B_TA1B601_1
(TUBULIN BETA CHAIN)		 6f9m SERINE PROTEASE
(Planococcus
plakortidis) 		5 / 12 VAL A 150
LEU A 306
SER A 152
LEU A 304
THR A 289
 None
 1.22A 2p4nB-6f9mA:
undetectable		 2p4nB-6f9mA:
10.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WBE_B_TA1B1439_1
(TUBULIN BETA-2B
CHAIN)		 6f9m SERINE PROTEASE
(Planococcus
plakortidis) 		5 / 12 VAL A 150
LEU A 306
SER A 152
LEU A 304
THR A 289
 None
 1.22A 2wbeB-6f9mA:
undetectable		 2wbeB-6f9mA:
10.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN5_A_FUNA1356_1
(THYROXINE-BINDING
GLOBULIN)		 6f9m SERINE PROTEASE
(Planococcus
plakortidis) 		5 / 11 SER A 154
ALA A 181
LEU A 285
LEU A 228
SER A 251
 None
 1.11A 2xn5A-6f9mA:
undetectable		 2xn5A-6f9mA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YY8_B_SAMB500_0
(UPF0106 PROTEIN
PH0461)		 6f9m SERINE PROTEASE
(Planococcus
plakortidis) 		5 / 11 LEU A 164
ILE A 134
HIS A 135
GLU A 166
ALA A 167
 None
 1.14A 2yy8A-6f9mA:
2.2
2yy8B-6f9mA:
undetectable		 2yy8A-6f9mA:
undetectable
2yy8B-6f9mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z0Y_A_SAMA300_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0657)		 6f9m SERINE PROTEASE
(Planococcus
plakortidis) 		5 / 9 ALA A  46
VAL A  44
VAL A 116
GLY A  65
ALA A 137
 None
 0.96A 2z0yA-6f9mA:
3.0		 2z0yA-6f9mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z0Y_B_SAMB400_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0657)		 6f9m SERINE PROTEASE
(Planococcus
plakortidis) 		5 / 9 ALA A  46
VAL A  44
VAL A 116
GLY A  65
ALA A 137
 None
 0.85A 2z0yB-6f9mA:
undetectable		 2z0yB-6f9mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCO_B_TA1B601_1
(BOVINE BETA TUBULIN)		 6f9m SERINE PROTEASE
(Planococcus
plakortidis) 		5 / 12 VAL A 150
LEU A 306
SER A 152
LEU A 304
THR A 289
 None
 1.22A 3dcoB-6f9mA:
undetectable		 3dcoB-6f9mA:
10.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EDL_B_TA1B601_1
(BETA TUBULIN)		 6f9m SERINE PROTEASE
(Planococcus
plakortidis) 		5 / 12 VAL A 150
LEU A 306
SER A 152
LEU A 304
THR A 289
 None
 1.22A 3edlB-6f9mA:
undetectable		 3edlB-6f9mA:
10.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IZ0_B_TA1B820_1
(BETA TUBULIN, CHAIN
B FROM PDB 1JFF)		 6f9m SERINE PROTEASE
(Planococcus
plakortidis) 		5 / 12 VAL A 150
LEU A 306
SER A 152
LEU A 304
THR A 289
 None
 1.20A 3iz0B-6f9mA:
undetectable		 3iz0B-6f9mA:
10.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9S_C_BEZC264_0
(CARNITINYL-COA
DEHYDRATASE)		 6f9m SERINE PROTEASE
(Planococcus
plakortidis) 		4 / 6 ALA A 260
ILE A 264
LEU A 306
ALA A 230
 None
 0.83A 3r9sC-6f9mA:
2.5		 3r9sC-6f9mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U8Q_A_NPUA7231_1
(LACTOTRANSFERRIN)		 6f9m SERINE PROTEASE
(Planococcus
plakortidis) 		4 / 5 THR A  70
GLY A  75
PRO A  77
ASN A  68
 None
 1.14A 3u8qA-6f9mA:
undetectable		 3u8qA-6f9mA:
12.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K7G_B_ACTB902_0
(3-HYDROXYPROLINE
DEHYDRATSE)		 6f9m SERINE PROTEASE
(Planococcus
plakortidis) 		4 / 7 PRO A 255
SER A 251
HIS A  86
SER A 154
 None
 1.16A 4k7gB-6f9mA:
undetectable		 4k7gB-6f9mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1E_B_C2FB4000_0
(DIHYDROPTEROATE
SYNTHASE DHPS)		 6f9m SERINE PROTEASE
(Planococcus
plakortidis) 		5 / 12 ILE A 179
ILE A 216
LEU A 292
GLY A 300
ILE A 226
 None
 1.16A 4o1eB-6f9mA:
undetectable		 4o1eB-6f9mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNW_B_TA1B902_1
(TUBULIN BETA-2B
CHAIN)		 6f9m SERINE PROTEASE
(Planococcus
plakortidis) 		5 / 12 VAL A 150
LEU A 306
SER A 152
LEU A 304
THR A 289
 None
 1.15A 5hnwB-6f9mA:
undetectable		 5hnwB-6f9mA:
10.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNY_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 6f9m SERINE PROTEASE
(Planococcus
plakortidis) 		5 / 12 VAL A 150
LEU A 306
SER A 152
LEU A 304
THR A 289
 None
 1.18A 5hnyB-6f9mA:
undetectable		 5hnyB-6f9mA:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_B_SAMB501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 6f9m SERINE PROTEASE
(Planococcus
plakortidis) 		3 / 3 SER A  97
ALA A  96
THR A 238
 None
NA  A 402 ( 4.7A)
None
 0.57A 5n0xB-6f9mA:
1.6		 5n0xB-6f9mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YK2_A_ERYA501_0
(PROBABLE CONSERVED
ATP-BINDING PROTEIN
ABC TRANSPORTER)		 6f9m SERINE PROTEASE
(Planococcus
plakortidis) 		5 / 11 GLY A 259
ALA A 260
ALA A 108
PRO A 109
VAL A  45
 None
 0.98A 5yk2A-6f9mA:
undetectable		 5yk2A-6f9mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_C_SUEC1203_1
(NS3 PROTEASE)		 6f9m SERINE PROTEASE
(Planococcus
plakortidis) 		5 / 9 VAL A 118
GLY A 133
ILE A  63
LEU A 113
ASP A  82
 None
 1.44A 6c2mC-6f9mA:
undetectable		 6c2mC-6f9mA:
26.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F88_B_STRB502_1
(CYTOCHROME P450
CYP260A1)		 6f9m SERINE PROTEASE
(Planococcus
plakortidis) 		4 / 6 LEU A 247
ALA A 245
LEU A   6
THR A  50
 None
 0.96A 6f88B-6f9mA:
undetectable		 6f88B-6f9mA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GH9_A_MIXA1003_0
(UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 15)		 6f9m SERINE PROTEASE
(Planococcus
plakortidis) 		4 / 5 ASN A  84
GLY A 249
HIS A  86
ASP A  49
 None
 1.29A 6gh9A-6f9mA:
undetectable		 6gh9A-6f9mA:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD4_B_STIB602_1
(TYROSINE-PROTEIN
KINASE ABL1)		 6f9m SERINE PROTEASE
(Planococcus
plakortidis) 		4 / 6 LEU A 247
TYR A   9
VAL A 204
GLY A  85
 None
None
PGE  A 401 (-4.5A)
None
 1.02A 6hd4B-6f9mA:
undetectable		 6hd4B-6f9mA:
12.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD6_A_STIA603_1
(TYROSINE-PROTEIN
KINASE ABL1)		 6f9m SERINE PROTEASE
(Planococcus
plakortidis) 		4 / 5 LEU A 247
TYR A   9
ILE A 151
GLY A  85
 None
 0.89A 6hd6A-6f9mA:
undetectable		 6hd6A-6f9mA:
12.35