SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6f9n'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_B_DVAB8_0
(GRAMICIDIN A)		 6f9n PRE-MRNA 3' END
PROCESSING PROTEIN
WDR33
(Homo
sapiens) 		3 / 3 VAL B 135
VAL B 124
TRP B 146
 None
 0.90A 1bdwA-6f9nB:
undetectable
1bdwB-6f9nB:
undetectable		 1bdwA-6f9nB:
undetectable
1bdwB-6f9nB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_A_803A311_1
(ANTIGEN CD11A (P180))		 6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1
(Homo
sapiens) 		5 / 10 LEU A 963
ILE A 899
GLU A 848
LEU A 864
VAL A 943
 None
 1.03A 1cqpA-6f9nA:
undetectable
1cqpB-6f9nA:
undetectable		 1cqpA-6f9nA:
19.23
1cqpB-6f9nA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_A_803A311_1
(ANTIGEN CD11A (P180))		 6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1
(Homo
sapiens) 		5 / 10 LEU A1182
ILE A1141
TYR A1164
GLU A1098
VAL A1172
 None
 1.13A 1cqpA-6f9nA:
undetectable
1cqpB-6f9nA:
undetectable		 1cqpA-6f9nA:
19.23
1cqpB-6f9nA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_0
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1
(Homo
sapiens) 		4 / 4 THR A 321
LEU A 322
LEU A 269
GLN A 207
 None
 1.03A 1fbmA-6f9nA:
undetectable		 1fbmA-6f9nA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1
(Homo
sapiens) 		4 / 7 GLY A1343
HIS A1307
THR A1340
THR A  35
 None
 0.91A 1gtfL-6f9nA:
undetectable
1gtfM-6f9nA:
undetectable		 1gtfL-6f9nA:
undetectable
1gtfM-6f9nA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JFF_B_TA1B601_1
(TUBULIN BETA CHAIN)		 6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1
PRE-MRNA 3' END
PROCESSING PROTEIN
WDR33
(Homo
sapiens) 		5 / 12 HIS B 384
SER B  62
THR B 150
ARG B 133
GLY A1187
 None
 1.06A 1jffB-6f9nB:
undetectable		 1jffB-6f9nB:
10.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_A_SAMA293_1
(GLYCINE
N-METHYLTRANSFERASE)		 6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1
(Homo
sapiens) 		4 / 5 ARG A1382
ASP A1342
ASN A 471
TYR A   5
 None
 1.37A 1nbiA-6f9nA:
1.5		 1nbiA-6f9nA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_B_SAMB1293_1
(GLYCINE
N-METHYLTRANSFERASE)		 6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1
(Homo
sapiens) 		4 / 5 ARG A1382
ASP A1342
ASN A 471
TYR A   5
 None
 1.37A 1nbiB-6f9nA:
1.5		 1nbiB-6f9nA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_J_FUAJ711_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1
(Homo
sapiens) 		4 / 4 ALA A1035
VAL A1025
ALA A1026
HIS A1028
 None
 1.25A 1q23K-6f9nA:
undetectable		 1q23K-6f9nA:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_A_SAMA801_1
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1
PRE-MRNA 3' END
PROCESSING PROTEIN
WDR33
(Homo
sapiens;
Homo
sapiens) 		4 / 6 ASP B  85
TYR B  88
ASP B  91
GLU A1061
 None
 1.29A 1rjdA-6f9nB:
undetectable		 1rjdA-6f9nB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_B_SAMB802_1
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1
PRE-MRNA 3' END
PROCESSING PROTEIN
WDR33
(Homo
sapiens;
Homo
sapiens) 		4 / 6 ASP B  85
TYR B  88
ASP B  91
GLU A1061
 None
 1.29A 1rjdB-6f9nB:
undetectable		 1rjdB-6f9nB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_C_SAMC803_1
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1
PRE-MRNA 3' END
PROCESSING PROTEIN
WDR33
(Homo
sapiens;
Homo
sapiens) 		4 / 6 ASP B  85
TYR B  88
ASP B  91
GLU A1061
 None
 1.28A 1rjdC-6f9nB:
undetectable		 1rjdC-6f9nB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN5_C_T3C601_2
(TRANSTHYRETIN)		 6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1
(Homo
sapiens) 		4 / 8 GLU A1165
THR A1125
ALA A1123
VAL A1100
 None
 0.85A 1sn5C-6f9nA:
undetectable		 1sn5C-6f9nA:
26.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V2X_A_SAMA400_0
(TRNA (GM18)
METHYLTRANSFERASE)		 6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1
(Homo
sapiens) 		5 / 12 GLY A1170
GLY A1137
ILE A1212
MET A1215
SER A1184
 None
 0.96A 1v2xA-6f9nA:
undetectable		 1v2xA-6f9nA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WSV_A_THHA3001_1
(AMINOMETHYLTRANSFERA
SE)		 6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1
PRE-MRNA 3' END
PROCESSING PROTEIN
WDR33
(Homo
sapiens;
Homo
sapiens) 		3 / 3 ASP B 409
GLU A1058
TYR A1066
 None
 0.75A 1wsvA-6f9nB:
undetectable		 1wsvA-6f9nB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X7P_A_SAMA301_0
(RRNA
METHYLTRANSFERASE)		 6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1
(Homo
sapiens) 		5 / 11 GLY A1170
GLY A1137
ILE A1212
MET A1215
SER A1184
 None
 0.96A 1x7pA-6f9nA:
undetectable
1x7pB-6f9nA:
undetectable		 1x7pA-6f9nA:
undetectable
1x7pB-6f9nA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_A_STRA1001_2
(MINERALOCORTICOID
RECEPTOR)		 6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1
(Homo
sapiens) 		4 / 4 LEU A 289
LEU A 286
SER A 285
LEU A 312
 None
 1.17A 1ya3A-6f9nA:
undetectable		 1ya3A-6f9nA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1436_1
(CHITINASE)		 6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1
(Homo
sapiens) 		3 / 3 ASP A 969
PHE A 490
ARG A 997
 None
 0.80A 2a3aA-6f9nA:
undetectable		 2a3aA-6f9nA:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DDW_A_PXLA1003_1
(PYRIDOXINE KINASE)		 6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1
PRE-MRNA 3' END
PROCESSING PROTEIN
WDR33
(Homo
sapiens) 		4 / 8 VAL B  63
VAL A1227
PRO B  95
ASP A1226
 None
 1.07A 2ddwA-6f9nB:
undetectable		 2ddwA-6f9nB:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HXF_B_TA1B601_1
(TUBULIN BETA CHAIN)		 6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1
PRE-MRNA 3' END
PROCESSING PROTEIN
WDR33
(Homo
sapiens) 		5 / 12 HIS B 384
SER B  62
THR B 150
ARG B 133
GLY A1187
 None
 1.06A 2hxfB-6f9nB:
undetectable		 2hxfB-6f9nB:
10.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HXH_B_TA1B601_1
(TUBULIN BETA CHAIN)		 6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1
PRE-MRNA 3' END
PROCESSING PROTEIN
WDR33
(Homo
sapiens) 		5 / 12 HIS B 384
SER B  62
THR B 150
ARG B 133
GLY A1187
 None
 1.06A 2hxhB-6f9nB:
undetectable		 2hxhB-6f9nB:
10.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P4N_B_TA1B601_1
(TUBULIN BETA CHAIN)		 6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1
PRE-MRNA 3' END
PROCESSING PROTEIN
WDR33
(Homo
sapiens) 		5 / 12 HIS B 384
SER B  62
THR B 150
ARG B 133
GLY A1187
 None
 1.06A 2p4nB-6f9nB:
undetectable		 2p4nB-6f9nB:
10.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q5K_A_AB1A201_1
(PROTEASE)		 6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1
PRE-MRNA 3' END
PROCESSING PROTEIN
WDR33
(Homo
sapiens) 		5 / 9 ASP B  58
VAL B  63
GLY A1187
ILE A1186
ILE B  64
 None
 0.97A 2q5kA-6f9nB:
undetectable		 2q5kA-6f9nB:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBN_A_CAMA442_0
(CYTOCHROME P450-CAM)		 6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1
(Homo
sapiens) 		4 / 7 TYR A 874
VAL A 813
VAL A 846
VAL A 867
 None
 0.97A 2qbnA-6f9nA:
undetectable		 2qbnA-6f9nA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WBE_B_TA1B1439_1
(TUBULIN BETA-2B
CHAIN)		 6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1
PRE-MRNA 3' END
PROCESSING PROTEIN
WDR33
(Homo
sapiens) 		5 / 12 HIS B 384
SER B  62
THR B 150
ARG B 133
GLY A1187
 None
 1.06A 2wbeB-6f9nB:
undetectable		 2wbeB-6f9nB:
10.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YOE_C_FL7C1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1
(Homo
sapiens) 		4 / 8 GLY A 389
ASN A 509
ILE A 344
SER A 391
 None
 0.89A 2yoeB-6f9nA:
undetectable
2yoeC-6f9nA:
undetectable		 2yoeB-6f9nA:
13.07
2yoeC-6f9nA:
13.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOC_C_ERYC3402_0
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1
(Homo
sapiens) 		5 / 12 PHE A 164
ILE A 247
PHE A 208
LEU A  96
GLU A 107
 None
 1.34A 3aocC-6f9nA:
undetectable		 3aocC-6f9nA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF502_3
(PHOSPHOLIPASE A2)		 6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1
(Homo
sapiens) 		5 / 12 ILE A 937
PRO A 977
PHE A 978
THR A 537
LYS A 569
 None
 1.27A 3bjwF-6f9nA:
undetectable		 3bjwF-6f9nA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 6f9n PRE-MRNA 3' END
PROCESSING PROTEIN
WDR33
(Homo
sapiens) 		4 / 4 SER B 263
GLY B 262
GLY B 244
GLY B 242
 None
 0.91A 3bogB-6f9nB:
undetectable
3bogD-6f9nB:
undetectable		 3bogB-6f9nB:
undetectable
3bogD-6f9nB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCO_B_TA1B601_1
(BOVINE BETA TUBULIN)		 6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1
PRE-MRNA 3' END
PROCESSING PROTEIN
WDR33
(Homo
sapiens) 		5 / 12 HIS B 384
SER B  62
THR B 150
ARG B 133
GLY A1187
 None
 1.06A 3dcoB-6f9nB:
undetectable		 3dcoB-6f9nB:
10.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EDL_B_TA1B601_1
(BETA TUBULIN)		 6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1
PRE-MRNA 3' END
PROCESSING PROTEIN
WDR33
(Homo
sapiens) 		5 / 12 HIS B 384
SER B  62
THR B 150
ARG B 133
GLY A1187
 None
 1.06A 3edlB-6f9nB:
undetectable		 3edlB-6f9nB:
10.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKX_B_1UNB201_1
(PROTEASE)		 6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1
PRE-MRNA 3' END
PROCESSING PROTEIN
WDR33
(Homo
sapiens) 		5 / 11 ASP B  58
VAL B  63
GLY A1187
ILE A1186
ILE B  64
 None
 0.96A 3ekxA-6f9nB:
undetectable		 3ekxA-6f9nB:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IZ0_B_TA1B820_1
(BETA TUBULIN, CHAIN
B FROM PDB 1JFF)		 6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1
PRE-MRNA 3' END
PROCESSING PROTEIN
WDR33
(Homo
sapiens) 		5 / 12 HIS B 384
SER B  62
THR B 150
ARG B 133
GLY A1187
 None
 1.05A 3iz0B-6f9nB:
undetectable		 3iz0B-6f9nB:
10.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_S_TFPS202_1
(PROTEIN S100-A4)		 6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1
(Homo
sapiens) 		4 / 6 LEU A 682
PHE A 668
ILE A 626
CYH A 649
 None
 1.01A 3ko0S-6f9nA:
undetectable		 3ko0S-6f9nA:
24.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NK7_A_SAMA770_0
(23S RRNA
METHYLTRANSFERASE)		 6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1
(Homo
sapiens) 		5 / 12 GLY A1170
GLY A1137
ILE A1212
MET A1215
SER A1184
 None
 1.06A 3nk7A-6f9nA:
undetectable		 3nk7A-6f9nA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SOA_A_DB8A445_1
(CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE TYPE II
SUBUNIT ALPHA WITH A
BETA 7 LINKER)		 6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1
(Homo
sapiens) 		4 / 6 VAL A1121
MET A1142
PHE A1160
VAL A1033
 None
 1.08A 3soaA-6f9nA:
undetectable		 3soaA-6f9nA:
11.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TEG_A_DAHA416_1
(PHENYLALANYL-TRNA
SYNTHETASE,
MITOCHONDRIAL)		 6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1
(Homo
sapiens) 		5 / 12 ARG A1276
THR A 372
GLY A  13
GLY A 385
GLY A  34
 None
 1.13A 3tegA-6f9nA:
undetectable		 3tegA-6f9nA:
10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKA_A_SAMA400_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE H)		 6f9n PRE-MRNA 3' END
PROCESSING PROTEIN
WDR33
(Homo
sapiens) 		5 / 12 GLY B 351
GLY B 354
HIS B 374
SER B 349
GLU B 207
 None
 1.26A 3tkaA-6f9nB:
undetectable		 3tkaA-6f9nB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U7S_A_017A202_1
(POL POLYPROTEIN)		 6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1
(Homo
sapiens) 		5 / 9 LEU A1296
ASP A1226
ILE A1212
ILE A1216
LEU A1233
 None
 1.11A 3u7sA-6f9nA:
undetectable		 3u7sA-6f9nA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_K_CLMK221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1
(Homo
sapiens) 		5 / 10 PHE A 123
LEU A  95
VAL A 143
PHE A 164
VAL A 105
 None
 1.50A 3u9fK-6f9nA:
undetectable		 3u9fK-6f9nA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW7_A_VPXA2001_2
(PROTEINASE-ACTIVATED
RECEPTOR 1, LYSOZYME)		 6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1
(Homo
sapiens) 		4 / 4 PRO A 483
LEU A1005
HIS A 964
LEU A 963
 None
 1.39A 3vw7A-6f9nA:
undetectable		 3vw7A-6f9nA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_30ZA1920_1
(ANDROGEN RECEPTOR)		 6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1
PRE-MRNA 3' END
PROCESSING PROTEIN
WDR33
(Homo
sapiens) 		4 / 6 PRO A 228
GLY A 229
ASN B 405
ASN B 104
 None
 0.91A 3zqtA-6f9nA:
undetectable		 3zqtA-6f9nA:
14.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AFT_D_QMRD301_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1
(Homo
sapiens) 		4 / 8 VAL A 788
TYR A 797
CYH A 785
VAL A 849
 None
 1.13A 4aftD-6f9nA:
undetectable
4aftE-6f9nA:
undetectable		 4aftD-6f9nA:
15.35
4aftE-6f9nA:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZS_A_SAMA1475_1
(METHYLTRANSFERASE
WBDD)		 6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1
PRE-MRNA 3' END
PROCESSING PROTEIN
WDR33
(Homo
sapiens;
Homo
sapiens) 		3 / 3 ARG B  74
ASP A 205
GLN A 207
 None
 0.79A 4azsA-6f9nB:
undetectable		 4azsA-6f9nB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O4D_A_ACTA406_0
(INOSITOL
HEXAKISPHOSPHATE
KINASE)		 6f9n PRE-MRNA 3' END
PROCESSING PROTEIN
WDR33
(Homo
sapiens) 		4 / 7 ASP B 214
THR B 213
PHE B 210
HIS B 171
 None
 1.22A 4o4dA-6f9nB:
undetectable		 4o4dA-6f9nB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QDJ_A_SAMA301_0
(MAGNESIUM-PROTOPORPH
YRIN
O-METHYLTRANSFERASE)		 6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1
(Homo
sapiens) 		5 / 12 VAL A  78
PHE A  74
GLY A1375
LEU A 103
LEU A 118
 None
 1.02A 4qdjA-6f9nA:
undetectable		 4qdjA-6f9nA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTB_A_SAMA501_1
(HYDG PROTEIN)		 6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1
(Homo
sapiens) 		3 / 3 GLU A1353
ARG A1357
GLN A1266
 None
 0.97A 4rtbA-6f9nA:
undetectable		 4rtbA-6f9nA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBE_A_2FAA401_1
(ADENOSINE KINASE)		 6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1
(Homo
sapiens) 		5 / 12 SER A 504
GLY A1343
GLY A 473
ASN A 471
ALA A 511
 None
 1.30A 4ubeA-6f9nA:
undetectable		 4ubeA-6f9nA:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_C_29SC601_2
(ESTROGEN RECEPTOR)		 6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1
(Homo
sapiens) 		4 / 6 LEU A 303
ASP A 323
ILE A1060
HIS A1068
 None
 1.09A 4xi3C-6f9nA:
undetectable		 4xi3C-6f9nA:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XV2_B_P06B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 6f9n PRE-MRNA 3' END
PROCESSING PROTEIN
WDR33
(Homo
sapiens) 		4 / 4 GLY B 244
VAL B 247
PHE B 272
ILE B 270
 None
 1.15A 4xv2B-6f9nB:
undetectable		 4xv2B-6f9nB:
13.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXD_A_RBVA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1
(Homo
sapiens) 		3 / 3 THR A 266
HIS A1068
LEU A 303
 None
 0.82A 5axdA-6f9nA:
undetectable		 5axdA-6f9nA:
11.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_A_ACTA403_0
(D-ALANINE--D-ALANINE
LIGASE)		 6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1
(Homo
sapiens) 		4 / 6 LYS A 364
GLY A 342
SER A 338
LEU A 339
 None
 1.08A 5bphA-6f9nA:
undetectable		 5bphA-6f9nA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_D_ACTD403_0
(D-ALANINE--D-ALANINE
LIGASE)		 6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1
(Homo
sapiens) 		4 / 6 LYS A 364
GLY A 342
SER A 338
LEU A 339
 None
 1.24A 5bphD-6f9nA:
undetectable		 5bphD-6f9nA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EU8_B_010B6_0
(N-[(5-METHYLISOXAZOL
-3-YL)CARBONYL]ALANY
L-L-VALYL-N~1~-((1R,
2Z)-4-(BENZYLOXY)-4-
OXO-1-{[(3R)-2-OXOPY
RROLIDIN-3-YL]METHYL
}BUT-2-ENYL)-L-LEUCI
NAMIDE
MAIN PROTEASE)		 6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1
(Homo
sapiens) 		4 / 5 LEU A1127
HIS A1099
THR A1101
CYH A1135
 None
 1.28A 5eu8A-6f9nA:
undetectable		 5eu8A-6f9nA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H5F_A_SAMA301_0
(PROTEIN ARGININE
N-METHYLTRANSFERASE
SFM1)		 6f9n PRE-MRNA 3' END
PROCESSING PROTEIN
WDR33
(Homo
sapiens) 		5 / 12 LEU B 356
PHE B 358
ARG B 328
LEU B 381
ALA B 348
 None
 1.12A 5h5fA-6f9nB:
undetectable		 5h5fA-6f9nB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_B_6V8B304_0
(PROTEASOME SUBUNIT
BETA TYPE-6
PROTEASOME SUBUNIT
BETA TYPE-7)		 6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1
(Homo
sapiens) 		5 / 12 TYR A1407
THR A1424
THR A1425
ALA A1419
THR A1355
 None
 1.18A 5lf7V-6f9nA:
undetectable
5lf7b-6f9nA:
undetectable		 5lf7V-6f9nA:
undetectable
5lf7b-6f9nA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_N_6V8N305_0
(PROTEASOME SUBUNIT
BETA TYPE-6
PROTEASOME SUBUNIT
BETA TYPE-7)		 6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1
(Homo
sapiens) 		5 / 12 TYR A1407
THR A1424
THR A1425
ALA A1419
THR A1355
 None
 1.18A 5lf7H-6f9nA:
undetectable
5lf7N-6f9nA:
undetectable		 5lf7H-6f9nA:
undetectable
5lf7N-6f9nA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OGC_B_TA1B601_1
(TUBULIN BETA CHAIN)		 6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1
PRE-MRNA 3' END
PROCESSING PROTEIN
WDR33
(Homo
sapiens) 		5 / 12 HIS B 384
SER B  62
THR B 150
ARG B 133
GLY A1187
 None
 1.06A 5ogcB-6f9nB:
undetectable		 5ogcB-6f9nB:
10.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGJ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1
(Homo
sapiens) 		3 / 3 VAL A 621
VAL A 607
GLN A 648
 None
 0.54A 5qgjA-6f9nA:
undetectable		 5qgjA-6f9nA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGM_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1
(Homo
sapiens) 		3 / 3 VAL A 621
VAL A 607
GLN A 648
 None
 0.55A 5qgmA-6f9nA:
undetectable		 5qgmA-6f9nA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGN_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1
(Homo
sapiens) 		3 / 3 VAL A 621
VAL A 607
GLN A 648
 None
 0.58A 5qgnA-6f9nA:
undetectable		 5qgnA-6f9nA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGY_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1
(Homo
sapiens) 		3 / 3 VAL A 621
VAL A 607
GLN A 648
 None
 0.64A 5qgyA-6f9nA:
undetectable		 5qgyA-6f9nA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGZ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1
(Homo
sapiens) 		3 / 3 VAL A 621
VAL A 607
GLN A 648
 None
 0.63A 5qgzA-6f9nA:
undetectable		 5qgzA-6f9nA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH0_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1
(Homo
sapiens) 		3 / 3 VAL A 621
VAL A 607
GLN A 648
 None
 0.63A 5qh0A-6f9nA:
undetectable		 5qh0A-6f9nA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH2_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1
(Homo
sapiens) 		3 / 3 VAL A 621
VAL A 607
GLN A 648
 None
 0.65A 5qh2A-6f9nA:
undetectable		 5qh2A-6f9nA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH3_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1
(Homo
sapiens) 		3 / 3 VAL A 621
VAL A 607
GLN A 648
 None
 0.64A 5qh3A-6f9nA:
undetectable		 5qh3A-6f9nA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH5_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1
(Homo
sapiens) 		3 / 3 VAL A 621
VAL A 607
GLN A 648
 None
 0.62A 5qh5A-6f9nA:
undetectable		 5qh5A-6f9nA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH6_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1
(Homo
sapiens) 		3 / 3 VAL A 621
VAL A 607
GLN A 648
 None
 0.60A 5qh6A-6f9nA:
undetectable		 5qh6A-6f9nA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH7_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1
(Homo
sapiens) 		3 / 3 VAL A 621
VAL A 607
GLN A 648
 None
 0.62A 5qh7A-6f9nA:
undetectable		 5qh7A-6f9nA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHA_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1
(Homo
sapiens) 		3 / 3 VAL A 621
VAL A 607
GLN A 648
 None
 0.62A 5qhaA-6f9nA:
undetectable		 5qhaA-6f9nA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHH_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1
(Homo
sapiens) 		3 / 3 VAL A 621
VAL A 607
GLN A 648
 None
 0.61A 5qhhA-6f9nA:
undetectable		 5qhhA-6f9nA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1
(Homo
sapiens) 		4 / 8 TYR A 701
THR A 782
GLN A 798
TRP A 784
 None
 1.23A 5tzoA-6f9nA:
undetectable		 5tzoA-6f9nA:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1
(Homo
sapiens) 		4 / 8 TYR A 701
THR A 782
GLN A 798
TRP A 784
 None
 1.26A 5tzoB-6f9nA:
undetectable		 5tzoB-6f9nA:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_C_7V7C202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1
(Homo
sapiens) 		4 / 8 TYR A 701
THR A 782
GLN A 798
TRP A 784
 None
 1.20A 5tzoC-6f9nA:
undetectable		 5tzoC-6f9nA:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_H_RITH602_2
(CYTOCHROME P450 3A5)		 6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1
(Homo
sapiens) 		4 / 5 ARG A 142
PHE A 221
LEU A 220
LEU A 159
 None
 1.25A 5veuH-6f9nA:
undetectable		 5veuH-6f9nA:
9.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YOD_D_BEZD201_0
(NS3 PROTEASE)		 6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1
(Homo
sapiens) 		4 / 5 ALA A1287
SER A1290
GLY A1293
TYR A1283
 None
 1.24A 5yodD-6f9nA:
undetectable		 5yodD-6f9nA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA412_0
(UNCHARACTERIZED
PROTEIN KDOO)		 6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1
(Homo
sapiens) 		3 / 3 LYS A  64
ASN A  44
SER A 856
 None
 0.81A 5yw0A-6f9nA:
undetectable		 5yw0A-6f9nA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_D_ECLD1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1
PRE-MRNA 3' END
PROCESSING PROTEIN
WDR33
(Homo
sapiens) 		4 / 7 ALA A1225
ILE B  64
LEU B  67
ILE A1186
 None
 0.87A 6b5vB-6f9nA:
undetectable
6b5vD-6f9nA:
undetectable		 6b5vB-6f9nA:
22.09
6b5vD-6f9nA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_B_SUEB1202_0
(NS3 PROTEASE)		 6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1
(Homo
sapiens) 		5 / 12 GLY A 986
VAL A 523
ARG A1014
GLY A 939
ALA A1003
 None
 1.18A 6c2mB-6f9nA:
undetectable		 6c2mB-6f9nA:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_A_EY4A501_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 6f9n PRE-MRNA 3' END
PROCESSING PROTEIN
WDR33
(Homo
sapiens) 		4 / 5 VAL B 260
TRP B 273
PRO B 275
THR B 283
 None
 1.43A 6cduA-6f9nB:
undetectable
6cduB-6f9nB:
undetectable		 6cduA-6f9nB:
undetectable
6cduB-6f9nB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_A_GMJA301_1
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1
(Homo
sapiens) 		4 / 6 SER A 582
ASP A 596
GLN A 603
GLU A 594
 None
 1.39A 6djzA-6f9nA:
undetectable		 6djzA-6f9nA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		 6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1
(Homo
sapiens) 		4 / 6 THR A 304
LEU A 303
THR A 314
LEU A 322
 None
 0.98A 6mvxA-6f9nA:
undetectable
6mvxB-6f9nA:
undetectable
6mvxC-6f9nA:
undetectable		 6mvxA-6f9nA:
undetectable
6mvxB-6f9nA:
undetectable
6mvxC-6f9nA:
undetectable