SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6fao'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CDQ_A_SAMA1500_0
(ASPARTOKINASE)		 6fao GLYCOSIDE HYDROLASE
FAMILY 6
(metagenome) 		4 / 8 ILE A 185
SER A 186
ASP A 157
LEU A 173
 None
 0.90A 2cdqA-6faoA:
undetectable		 2cdqA-6faoA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FXE_A_DR7A102_2
(POL PROTEIN)		 6fao GLYCOSIDE HYDROLASE
FAMILY 6
(metagenome) 		5 / 11 GLY A 142
ALA A 141
ILE A  75
ILE A 113
ILE A  98
 None
 0.91A 2fxeB-6faoA:
undetectable		 2fxeB-6faoA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_G_SVRG506_2
(PHOSPHOLIPASE A2)		 6fao GLYCOSIDE HYDROLASE
FAMILY 6
(metagenome) 		4 / 5 VAL A 217
VAL A 218
PHE A 156
ARG A 222
 None
 1.26A 3bjwB-6faoA:
undetectable		 3bjwB-6faoA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CAS_A_ASDA332_1
(3-OXO-5-BETA-STEROID
4-DEHYDROGENASE)		 6fao GLYCOSIDE HYDROLASE
FAMILY 6
(metagenome) 		5 / 10 TRP A  97
TYR A  94
SER A 186
VAL A 154
LEU A 145
 None
 1.45A 3casA-6faoA:
4.8		 3casA-6faoA:
13.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJO_A_EAAA211_1
(GLUTATHIONE
S-TRANSFERASE P)		 6fao GLYCOSIDE HYDROLASE
FAMILY 6
(metagenome) 		4 / 8 VAL A  54
GLN A 151
ILE A  98
GLY A 104
 None
 0.95A 3hjoA-6faoA:
undetectable		 3hjoA-6faoA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB513_1
(HEMOLYTIC LECTIN
CEL-III)		 6fao GLYCOSIDE HYDROLASE
FAMILY 6
(metagenome) 		4 / 6 THR A 195
ASN A 223
ASP A 219
ILE A 260
 None
 1.45A 3w9tB-6faoA:
undetectable		 3w9tB-6faoA:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HP1_A_PPFA602_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 6fao GLYCOSIDE HYDROLASE
FAMILY 6
(metagenome) 		4 / 6 LYS A 261
ARG A 222
GLY A 268
ASP A 235
 EDO  A 301 (-2.8A)
None
None
None
 1.21A 5hp1A-6faoA:
undetectable		 5hp1A-6faoA:
8.67