SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6fay'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D0V_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 6fay ODZ3 PROTEIN
(Mus
musculus) 		4 / 8 GLY A1759
GLY A1727
LEU A1728
GLY A2013
 None
 0.68A 1d0vA-6fayA:
undetectable		 1d0vA-6fayA:
13.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_B_ADNB602_2
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 6fay ODZ3 PROTEIN
(Mus
musculus) 		4 / 5 THR A1643
THR A1644
GLU A1002
THR A1004
 None
 1.33A 1d4fB-6fayA:
undetectable		 1d4fB-6fayA:
10.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA206_1
(CARDIAC TROPONIN C)		 6fay ODZ3 PROTEIN
(Mus
musculus) 		4 / 8 GLN A2011
PRO A2014
ASP A2017
ARG A2018
 None
 1.20A 1dtlA-6fayA:
undetectable		 1dtlA-6fayA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM4_A_DXCA1001_0
(MAJOR POLLEN
ALLERGEN BET V 1-L)		 6fay ODZ3 PROTEIN
(Mus
musculus) 		5 / 12 PHE A2398
PRO A2397
THR A1879
ILE A1896
GLN A1892
 None
 1.18A 1fm4A-6fayA:
undetectable		 1fm4A-6fayA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IIU_A_RTLA176_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 6fay ODZ3 PROTEIN
(Mus
musculus) 		5 / 11 LEU A2269
ALA A2031
TYR A2266
LEU A2248
HIS A2277
 None
 1.26A 1iiuA-6fayA:
undetectable		 1iiuA-6fayA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JDV_E_ADNE4260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 6fay ODZ3 PROTEIN
(Mus
musculus) 		5 / 12 ARG A2475
GLY A1141
GLU A1114
GLU A1144
SER A1014
 None
 1.44A 1jdvE-6fayA:
undetectable
1jdvF-6fayA:
undetectable		 1jdvE-6fayA:
16.03
1jdvF-6fayA:
16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHA_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 6fay ODZ3 PROTEIN
(Mus
musculus) 		4 / 8 GLY A1759
GLY A1727
LEU A1728
GLY A2013
 None
 0.71A 1jhaA-6fayA:
undetectable		 1jhaA-6fayA:
13.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NW3_A_ACTA600_0
(HISTONE
METHYLTRANSFERASE
DOT1L)		 6fay ODZ3 PROTEIN
(Mus
musculus) 		4 / 5 LEU A2269
VAL A2043
TYR A2035
THR A2270
 None
 1.19A 1nw3A-6fayA:
undetectable		 1nw3A-6fayA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NW3_A_SAMA500_0
(HISTONE
METHYLTRANSFERASE
DOT1L)		 6fay ODZ3 PROTEIN
(Mus
musculus) 		5 / 12 GLU A2307
VAL A2090
ALA A2320
PHE A2111
ASN A2325
 None
 1.28A 1nw3A-6fayA:
undetectable		 1nw3A-6fayA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_I_URFI2041_1
(URIDINE
PHOSPHORYLASE)		 6fay ODZ3 PROTEIN
(Mus
musculus) 		4 / 8 THR A2094
GLN A2294
ILE A2085
VAL A2077
 None
 0.99A 1rxcI-6fayA:
undetectable		 1rxcI-6fayA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLS_B_C2FB266_0
(THYMIDYLATE SYNTHASE)		 6fay ODZ3 PROTEIN
(Mus
musculus) 		5 / 12 HIS A2355
ILE A2366
GLY A2369
PHE A2368
TYR A2266
 None
 1.11A 1tlsB-6fayA:
undetectable		 1tlsB-6fayA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BDM_A_TMIA501_1
(CYTOCHROME P450 2B4)		 6fay ODZ3 PROTEIN
(Mus
musculus) 		4 / 7 LEU A2358
GLY A2356
THR A2317
ILE A2332
 None
 1.08A 2bdmA-6fayA:
undetectable		 2bdmA-6fayA:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTJ_B_THRB402_0
(ASPARTOKINASE)		 6fay ODZ3 PROTEIN
(Mus
musculus) 		5 / 9 ILE A1330
GLY A1292
GLU A1296
ALA A1294
THR A1276
 None
 1.39A 2dtjA-6fayA:
undetectable
2dtjB-6fayA:
undetectable		 2dtjA-6fayA:
undetectable
2dtjB-6fayA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_F_TACF3888_1
(ELONGATION FACTOR
EF-TU)		 6fay ODZ3 PROTEIN
(Mus
musculus) 		4 / 7 SER A1830
ASP A2081
SER A1829
LEU A1791
 None
 0.92A 2hdnE-6fayA:
undetectable
2hdnF-6fayA:
undetectable
2hdnH-6fayA:
undetectable		 2hdnE-6fayA:
18.99
2hdnF-6fayA:
13.43
2hdnH-6fayA:
13.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_H_TACH4888_1
(ELONGATION FACTOR
EF-TU)		 6fay ODZ3 PROTEIN
(Mus
musculus) 		4 / 7 SER A1829
LEU A1791
SER A1830
ASP A2081
 None
 0.92A 2hdnF-6fayA:
undetectable
2hdnG-6fayA:
undetectable
2hdnH-6fayA:
undetectable		 2hdnF-6fayA:
13.43
2hdnG-6fayA:
18.99
2hdnH-6fayA:
13.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KOT_A_ANWA99_0
(PROTEIN S100-A13)		 6fay ODZ3 PROTEIN
(Mus
musculus) 		4 / 7 VAL A1996
PHE A1984
THR A1985
ARG A1967
 None
 1.02A 2kotA-6fayA:
undetectable		 2kotA-6fayA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KOT_A_ANWA99_0
(PROTEIN S100-A13)		 6fay ODZ3 PROTEIN
(Mus
musculus) 		4 / 7 VAL A1996
THR A1995
PHE A1984
ARG A1967
 None
 1.09A 2kotA-6fayA:
undetectable		 2kotA-6fayA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QL8_A_BEZA143_0
(PUTATIVE REDOX
PROTEIN)		 6fay ODZ3 PROTEIN
(Mus
musculus) 		4 / 7 ALA A1571
THR A1570
ARG A1584
TYR A1563
 None
 0.94A 2ql8A-6fayA:
undetectable
2ql8B-6fayA:
undetectable		 2ql8A-6fayA:
undetectable
2ql8B-6fayA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2REZ_A_ACTA155_0
(MULTIFUNCTIONAL
CYCLASE-DEHYDRATASE-
3-O-METHYL
TRANSFERASE TCMN)		 6fay ODZ3 PROTEIN
(Mus
musculus) 		4 / 5 TRP A2460
GLY A2439
PRO A2438
PHE A2041
 None
 1.44A 2rezA-6fayA:
undetectable		 2rezA-6fayA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W1B_A_DXCA2034_0
(ACRIFLAVIN
RESISTANCE PROTEIN B)		 6fay ODZ3 PROTEIN
(Mus
musculus) 		3 / 3 PHE A 983
SER A1692
LEU A1694
 None
 0.81A 2w1bA-6fayA:
undetectable		 2w1bA-6fayA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XNR_A_ACTA1001_0
(NUCLEAR
POLYADENYLATED
RNA-BINDING PROTEIN
3)		 6fay ODZ3 PROTEIN
(Mus
musculus) 		3 / 3 SER A1861
ARG A1864
GLN A1862
 None
 1.03A 2xnrA-6fayA:
undetectable		 2xnrA-6fayA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_B_ACHB1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 6fay ODZ3 PROTEIN
(Mus
musculus) 		4 / 8 TYR A1926
SER A2510
GLN A1919
ILE A1930
 None
 1.02A 2xz5B-6fayA:
undetectable
2xz5E-6fayA:
undetectable		 2xz5B-6fayA:
undetectable
2xz5E-6fayA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 6fay ODZ3 PROTEIN
(Mus
musculus) 		4 / 5 ILE A2391
TYR A1895
MET A1910
THR A1909
 None
 1.45A 3abkN-6fayA:
undetectable
3abkW-6fayA:
undetectable		 3abkN-6fayA:
undetectable
3abkW-6fayA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_C_ACTC610_0
(GBAA_1210 PROTEIN)		 6fay ODZ3 PROTEIN
(Mus
musculus) 		3 / 3 ASN A2314
ALA A2409
ARG A2131
 None
 0.88A 3tj7C-6fayA:
undetectable
3tj7D-6fayA:
undetectable		 3tj7C-6fayA:
undetectable
3tj7D-6fayA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYE_B_YTZB902_1
(DIHYDROPTEROATE
SYNTHASE)		 6fay ODZ3 PROTEIN
(Mus
musculus) 		3 / 3 PHE A1964
LYS A2226
SER A2225
 None
 1.27A 3tyeB-6fayA:
undetectable		 3tyeB-6fayA:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UY4_A_PAUA302_0
(PANTOTHENATE
SYNTHETASE)		 6fay ODZ3 PROTEIN
(Mus
musculus) 		4 / 8 HIS A1128
VAL A1130
ASP A1116
ARG A1584
 None
 1.09A 3uy4A-6fayA:
3.0		 3uy4A-6fayA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VXI_A_ASCA502_0
(DYP)		 6fay ODZ3 PROTEIN
(Mus
musculus) 		4 / 5 ASN A2168
ARG A2166
PRO A2188
HIS A2176
 None
 1.47A 3vxiA-6fayA:
undetectable		 3vxiA-6fayA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A3U_B_NCAB1359_0
(NADH:FLAVIN
OXIDOREDUCTASE/NADH
OXIDASE)		 6fay ODZ3 PROTEIN
(Mus
musculus) 		4 / 7 THR A2335
TRP A2165
TYR A2146
TYR A2341
 None
 1.32A 4a3uB-6fayA:
undetectable		 4a3uB-6fayA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6N_A_T1CA392_1
(TETX2 PROTEIN)		 6fay ODZ3 PROTEIN
(Mus
musculus) 		5 / 11 ARG A1797
PHE A1779
ASN A1777
ALA A1740
ASN A1744
 None
 1.26A 4a6nA-6fayA:
undetectable		 4a6nA-6fayA:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AGA_A_ACTA1131_0
(LYSOZYME C)		 6fay ODZ3 PROTEIN
(Mus
musculus) 		3 / 3 ASN A1371
ASP A1308
ASN A1310
 None
 0.73A 4agaA-6fayA:
undetectable		 4agaA-6fayA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZS_A_SAMA1475_0
(METHYLTRANSFERASE
WBDD)		 6fay ODZ3 PROTEIN
(Mus
musculus) 		5 / 12 GLN A1383
ALA A1393
ARG A1446
ILE A1434
GLU A1436
 None
 1.12A 4azsA-6fayA:
undetectable		 4azsA-6fayA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOG_A_C2FA302_0
(THYMIDYLATE SYNTHASE)		 6fay ODZ3 PROTEIN
(Mus
musculus) 		5 / 11 HIS A2355
ILE A2366
GLY A2369
PHE A2368
TYR A2266
 None
 1.12A 4fogA-6fayA:
undetectable		 4fogA-6fayA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOG_C_C2FC302_0
(THYMIDYLATE SYNTHASE)		 6fay ODZ3 PROTEIN
(Mus
musculus) 		5 / 11 HIS A2355
ILE A2366
GLY A2369
PHE A2368
TYR A2266
 None
 1.16A 4fogC-6fayA:
undetectable		 4fogC-6fayA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOX_A_D16A301_1
(THYMIDYLATE SYNTHASE)		 6fay ODZ3 PROTEIN
(Mus
musculus) 		5 / 12 HIS A2355
ILE A2366
GLY A2369
PHE A2368
TYR A2266
 None
 1.17A 4foxA-6fayA:
undetectable		 4foxA-6fayA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOX_E_D16E301_1
(THYMIDYLATE SYNTHASE)		 6fay ODZ3 PROTEIN
(Mus
musculus) 		5 / 12 HIS A2355
ILE A2366
GLY A2369
PHE A2368
TYR A2266
 None
 1.17A 4foxE-6fayA:
undetectable		 4foxE-6fayA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOX_F_D16F301_1
(THYMIDYLATE SYNTHASE)		 6fay ODZ3 PROTEIN
(Mus
musculus) 		5 / 11 HIS A2355
ILE A2366
GLY A2369
PHE A2368
TYR A2266
 None
 1.24A 4foxF-6fayA:
undetectable		 4foxF-6fayA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOX_G_D16G301_1
(THYMIDYLATE SYNTHASE)		 6fay ODZ3 PROTEIN
(Mus
musculus) 		5 / 12 HIS A2355
ILE A2366
GLY A2369
PHE A2368
TYR A2266
 None
 1.16A 4foxG-6fayA:
undetectable		 4foxG-6fayA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOX_H_D16H301_1
(THYMIDYLATE SYNTHASE)		 6fay ODZ3 PROTEIN
(Mus
musculus) 		5 / 11 HIS A2355
ILE A2366
GLY A2369
PHE A2368
TYR A2266
 None
 1.28A 4foxH-6fayA:
undetectable		 4foxH-6fayA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FQS_A_LYAA302_1
(THYMIDYLATE SYNTHASE)		 6fay ODZ3 PROTEIN
(Mus
musculus) 		5 / 12 HIS A2355
ILE A2366
GLY A2369
PHE A2368
TYR A2266
 None
 1.17A 4fqsA-6fayA:
undetectable		 4fqsA-6fayA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FQS_B_LYAB302_1
(THYMIDYLATE SYNTHASE)		 6fay ODZ3 PROTEIN
(Mus
musculus) 		5 / 12 HIS A2355
ILE A2366
GLY A2369
PHE A2368
TYR A2266
 None
 1.20A 4fqsB-6fayA:
undetectable		 4fqsB-6fayA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU8_A_ACTA304_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 6fay ODZ3 PROTEIN
(Mus
musculus) 		3 / 3 ARG A2251
HIS A2367
TYR A2243
 None
 1.23A 4fu8A-6fayA:
undetectable		 4fu8A-6fayA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU9_A_ACTA312_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 6fay ODZ3 PROTEIN
(Mus
musculus) 		3 / 3 ARG A2251
HIS A2367
TYR A2243
 None
 1.17A 4fu9A-6fayA:
undetectable		 4fu9A-6fayA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4H2F_A_ADNA601_1
(5'-NUCLEOTIDASE)		 6fay ODZ3 PROTEIN
(Mus
musculus) 		5 / 9 GLY A2356
GLY A2357
PHE A2368
GLY A2316
PHE A2354
 None
 1.37A 4h2fA-6fayA:
undetectable		 4h2fA-6fayA:
10.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4H2G_A_ADNA603_1
(5'-NUCLEOTIDASE)		 6fay ODZ3 PROTEIN
(Mus
musculus) 		5 / 9 GLY A2356
GLY A2357
PHE A2368
GLY A2316
PHE A2354
 None
 1.46A 4h2gA-6fayA:
undetectable		 4h2gA-6fayA:
10.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_D_AERD601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 6fay ODZ3 PROTEIN
(Mus
musculus) 		4 / 5 TYR A1481
GLY A1718
GLU A1735
VAL A1763
 None
 1.08A 4nkvD-6fayA:
undetectable		 4nkvD-6fayA:
10.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QGI_A_ROCA101_1
(PROTEASE)		 6fay ODZ3 PROTEIN
(Mus
musculus) 		5 / 11 ASP A1505
ILE A1445
GLY A1459
ILE A1460
THR A1437
 None
 0.97A 4qgiA-6fayA:
undetectable		 4qgiA-6fayA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTM_A_SAMA301_0
(DNA ADENINE
METHYLASE)		 6fay ODZ3 PROTEIN
(Mus
musculus) 		6 / 12 GLY A2356
GLY A2357
ILE A2103
ASN A2314
TYR A2291
GLN A2084
 None
 1.25A 4rtmA-6fayA:
undetectable		 4rtmA-6fayA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_F_377F402_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 6fay ODZ3 PROTEIN
(Mus
musculus) 		5 / 8 ALA A1236
ALA A1188
ALA A1494
SER A1492
ALA A1306
 None
 1.46A 4twdF-6fayA:
undetectable
4twdG-6fayA:
undetectable
4twdH-6fayA:
undetectable
4twdI-6fayA:
undetectable
4twdJ-6fayA:
undetectable		 4twdF-6fayA:
18.57
4twdG-6fayA:
18.57
4twdH-6fayA:
18.57
4twdI-6fayA:
18.57
4twdJ-6fayA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUD_A_SAMA303_0
(CATECHOL
O-METHYLTRANSFERASE)		 6fay ODZ3 PROTEIN
(Mus
musculus) 		5 / 12 GLU A1946
TYR A1944
TYR A1926
SER A 991
GLN A2471
 None
 1.47A 4xudA-6fayA:
undetectable		 4xudA-6fayA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_G_MZMG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 6fay ODZ3 PROTEIN
(Mus
musculus) 		5 / 12 LYS A1140
ASN A1142
HIS A1129
HIS A1546
THR A1549
 None
 1.33A 4yhaG-6fayA:
undetectable		 4yhaG-6fayA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YVX_A_GMRA401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 6fay ODZ3 PROTEIN
(Mus
musculus) 		5 / 12 LEU A2269
TYR A2035
LEU A2454
SER A2457
PHE A2021
 None
 1.25A 4yvxA-6fayA:
undetectable		 4yvxA-6fayA:
15.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTG_E_LFXE101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 6fay ODZ3 PROTEIN
(Mus
musculus) 		4 / 6 ALA A1616
ARG A1904
GLY A2497
GLU A2499
 None
 0.91A 5btgA-6fayA:
undetectable
5btgB-6fayA:
undetectable
5btgC-6fayA:
undetectable		 5btgA-6fayA:
11.41
5btgB-6fayA:
16.53
5btgC-6fayA:
11.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_H_SAMH301_1
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 6fay ODZ3 PROTEIN
(Mus
musculus) 		4 / 5 THR A1449
GLY A1430
GLU A1104
ASP A1451
 None
 1.20A 5c0oH-6fayA:
undetectable		 5c0oH-6fayA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I6X_A_8PRA705_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 6fay ODZ3 PROTEIN
(Mus
musculus) 		5 / 10 ILE A1313
TYR A1314
GLY A1328
GLY A1311
VAL A1273
 None
 1.18A 5i6xA-6fayA:
undetectable		 5i6xA-6fayA:
12.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_A_VDYA201_1
(CDL2.2)		 6fay ODZ3 PROTEIN
(Mus
musculus) 		5 / 12 LEU A1125
MET A1120
ILE A1006
GLU A1536
THR A1549
 None
 1.34A 5ienA-6fayA:
undetectable		 5ienA-6fayA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_A_VDYA201_1
(CDL2.2)		 6fay ODZ3 PROTEIN
(Mus
musculus) 		5 / 12 MET A1120
ILE A1006
GLU A1536
THR A1549
LEU A1580
 None
 1.02A 5ienA-6fayA:
undetectable		 5ienA-6fayA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGV_A_ZITA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 6fay ODZ3 PROTEIN
(Mus
musculus) 		5 / 12 GLY A2316
GLU A2132
ALA A2336
ILE A2135
TYR A2116
 None
 1.08A 5igvA-6fayA:
undetectable		 5igvA-6fayA:
13.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_A_ADNA502_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 6fay ODZ3 PROTEIN
(Mus
musculus) 		4 / 4 GLU A1003
THR A1004
THR A1644
LEU A1000
 None
 1.36A 5v96A-6fayA:
undetectable		 5v96A-6fayA:
12.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_B_ADNB502_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 6fay ODZ3 PROTEIN
(Mus
musculus) 		4 / 4 GLU A1003
THR A1004
THR A1644
LEU A1000
 None
 1.37A 5v96B-6fayA:
undetectable		 5v96B-6fayA:
12.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_C_ADNC502_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 6fay ODZ3 PROTEIN
(Mus
musculus) 		4 / 4 GLU A1003
THR A1004
THR A1644
LEU A1000
 None
 1.39A 5v96C-6fayA:
undetectable		 5v96C-6fayA:
12.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_D_ADND502_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 6fay ODZ3 PROTEIN
(Mus
musculus) 		4 / 4 GLU A1003
THR A1004
THR A1644
LEU A1000
 None
 1.37A 5v96D-6fayA:
undetectable		 5v96D-6fayA:
12.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCE_A_RITA602_2
(CYTOCHROME P450 3A4)		 6fay ODZ3 PROTEIN
(Mus
musculus) 		4 / 6 ARG A2008
ARG A2032
PHE A2023
ILE A2050
 None
 1.10A 5vceA-6fayA:
undetectable		 5vceA-6fayA:
10.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VIM_A_SAMA301_1
(METHYLTRANSFERASE)		 6fay ODZ3 PROTEIN
(Mus
musculus) 		4 / 4 SER A1575
THR A1554
ASP A1796
ASP A1818
 None
 1.16A 5vimA-6fayA:
undetectable		 5vimA-6fayA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VIM_B_SAMB301_1
(METHYLTRANSFERASE)		 6fay ODZ3 PROTEIN
(Mus
musculus) 		4 / 4 SER A1575
THR A1554
ASP A1796
ASP A1818
 None
 1.16A 5vimB-6fayA:
undetectable		 5vimB-6fayA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZW4_A_SAMA302_1
(PUTATIVE
O-METHYLTRANSFERASE
YRRM)		 6fay ODZ3 PROTEIN
(Mus
musculus) 		4 / 6 SER A1331
ARG A1256
ASP A1243
ASP A1325
 None
 1.17A 5zw4A-6fayA:
undetectable		 5zw4A-6fayA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GB9_A_ACTA508_0
(MOLYBDOPTERIN
BIOSYNTHESIS PROTEIN
CNX1)		 6fay ODZ3 PROTEIN
(Mus
musculus) 		3 / 3 VAL A1992
ALA A1990
GLN A2011
 None
 0.59A 6gb9A-6fayA:
undetectable		 6gb9A-6fayA:
undetectable