SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6fbk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEO_A_SAMA328_0
(MODIFICATION
METHYLASE HHAI)		 6fbk SERINE/THREONINE-PRO
TEIN KINASE WNK2
SERINE/THREONINE-PRO
TEIN KINASE WNK1
(Homo
sapiens;
Homo
sapiens) 		5 / 12 PHE A 498
GLY P1255
ASP A 501
ILE A 532
LEU A 476
 None
 0.91A 3eeoA-6fbkA:
undetectable		 3eeoA-6fbkA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KR3_A_GLYA701_0
(GLYCINE--TRNA LIGASE)		 6fbk SERINE/THREONINE-PRO
TEIN KINASE WNK2
SERINE/THREONINE-PRO
TEIN KINASE WNK1
(Homo
sapiens;
Homo
sapiens) 		4 / 6 GLU A 505
GLU A 509
ARG P1256
GLU A 513
 None
 1.21A 4kr3A-6fbkA:
undetectable		 4kr3A-6fbkA:
undetectable