SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6fbt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A52_A_ESTA1_1
(ESTROGEN RECEPTOR)		 6fbt LYTIC MUREIN
TRANSGLYCOSYLASE
(Pseudomonas
aeruginosa) 		5 / 10 ALA A 293
LEU A 316
LEU A 317
ARG A 322
LEU A 283
 None
 1.46A 1a52A-6fbtA:
undetectable		 1a52A-6fbtA:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_H_ACTH3006_0
(BETA-CARBONIC
ANHYDRASE)		 6fbt LYTIC MUREIN
TRANSGLYCOSYLASE
(Pseudomonas
aeruginosa) 		4 / 6 GLN A 629
ASP A 633
VAL A 570
HIS A 635
 None
 1.43A 1ekjG-6fbtA:
undetectable
1ekjH-6fbtA:
undetectable		 1ekjG-6fbtA:
undetectable
1ekjH-6fbtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_A_ESTA600_1
(ESTROGEN RECEPTOR)		 6fbt LYTIC MUREIN
TRANSGLYCOSYLASE
(Pseudomonas
aeruginosa) 		5 / 9 ALA A 293
LEU A 316
LEU A 317
ARG A 322
LEU A 283
 None
 1.46A 1ereA-6fbtA:
undetectable		 1ereA-6fbtA:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_B_ESTB600_1
(ESTROGEN RECEPTOR)		 6fbt LYTIC MUREIN
TRANSGLYCOSYLASE
(Pseudomonas
aeruginosa) 		5 / 9 ALA A 293
LEU A 316
LEU A 317
ARG A 322
LEU A 283
 None
 1.48A 1ereB-6fbtA:
undetectable		 1ereB-6fbtA:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_C_ESTC600_1
(ESTROGEN RECEPTOR)		 6fbt LYTIC MUREIN
TRANSGLYCOSYLASE
(Pseudomonas
aeruginosa) 		5 / 9 ALA A 293
LEU A 316
LEU A 317
ARG A 322
LEU A 283
 None
 1.46A 1ereC-6fbtA:
undetectable		 1ereC-6fbtA:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_D_ESTD600_1
(ESTROGEN RECEPTOR)		 6fbt LYTIC MUREIN
TRANSGLYCOSYLASE
(Pseudomonas
aeruginosa) 		5 / 9 ALA A 293
LEU A 316
LEU A 317
ARG A 322
LEU A 283
 None
 1.46A 1ereD-6fbtA:
undetectable		 1ereD-6fbtA:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GRM_A_DVAA6_0
(GRAMICIDIN A)		 6fbt LYTIC MUREIN
TRANSGLYCOSYLASE
(Pseudomonas
aeruginosa) 		3 / 3 ALA A 188
VAL A 155
TRP A 153
 None
 0.66A 1grmA-6fbtA:
undetectable		 1grmA-6fbtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GRM_B_DVAB6_0
(GRAMICIDIN A)		 6fbt LYTIC MUREIN
TRANSGLYCOSYLASE
(Pseudomonas
aeruginosa) 		3 / 3 ALA A 188
VAL A 155
TRP A 153
 None
 0.66A 1grmB-6fbtA:
undetectable		 1grmB-6fbtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_B_115B1_2
(HMG-COA REDUCTASE)		 6fbt LYTIC MUREIN
TRANSGLYCOSYLASE
(Pseudomonas
aeruginosa) 		4 / 8 VAL A 619
SER A 616
ASN A 613
ASP A 373
 None
 1.20A 1hwiB-6fbtA:
undetectable		 1hwiB-6fbtA:
10.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_C_115C4_1
(HMG-COA REDUCTASE)		 6fbt LYTIC MUREIN
TRANSGLYCOSYLASE
(Pseudomonas
aeruginosa) 		4 / 7 VAL A 619
SER A 616
ASN A 613
ASP A 373
 None
 1.24A 1hwiC-6fbtA:
undetectable		 1hwiC-6fbtA:
10.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_D_115D3_2
(HMG-COA REDUCTASE)		 6fbt LYTIC MUREIN
TRANSGLYCOSYLASE
(Pseudomonas
aeruginosa) 		4 / 7 VAL A 619
SER A 616
ASN A 613
ASP A 373
 None
 1.25A 1hwiD-6fbtA:
undetectable		 1hwiD-6fbtA:
10.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_A_117A2_1
(HMG-COA REDUCTASE)		 6fbt LYTIC MUREIN
TRANSGLYCOSYLASE
(Pseudomonas
aeruginosa) 		4 / 8 VAL A 619
SER A 616
ASN A 613
ASP A 373
 None
 1.22A 1hwkA-6fbtA:
undetectable		 1hwkA-6fbtA:
10.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_C_117C4_1
(HMG-COA REDUCTASE)		 6fbt LYTIC MUREIN
TRANSGLYCOSYLASE
(Pseudomonas
aeruginosa) 		4 / 8 VAL A 619
SER A 616
ASN A 613
ASP A 373
 None
 1.21A 1hwkC-6fbtA:
undetectable		 1hwkC-6fbtA:
10.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWK_D_117D3_2
(HMG-COA REDUCTASE)		 6fbt LYTIC MUREIN
TRANSGLYCOSYLASE
(Pseudomonas
aeruginosa) 		4 / 8 VAL A 619
SER A 616
ASN A 613
ASP A 373
 None
 1.20A 1hwkD-6fbtA:
undetectable		 1hwkD-6fbtA:
10.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO3_A_DVAA6_0
(GRAMICIDIN B)		 6fbt LYTIC MUREIN
TRANSGLYCOSYLASE
(Pseudomonas
aeruginosa) 		3 / 3 ALA A 188
VAL A 155
TRP A 153
 None
 0.93A 1jo3A-6fbtA:
undetectable		 1jo3A-6fbtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO3_B_DVAB6_0
(GRAMICIDIN B)		 6fbt LYTIC MUREIN
TRANSGLYCOSYLASE
(Pseudomonas
aeruginosa) 		3 / 3 ALA A 188
VAL A 155
TRP A 153
 None
 0.93A 1jo3B-6fbtA:
undetectable		 1jo3B-6fbtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO4_A_DVAA6_0
(GRAMICIDIN C)		 6fbt LYTIC MUREIN
TRANSGLYCOSYLASE
(Pseudomonas
aeruginosa) 		3 / 3 ALA A 188
VAL A 155
TRP A 153
 None
 0.78A 1jo4A-6fbtA:
undetectable		 1jo4A-6fbtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO4_B_DVAB6_0
(GRAMICIDIN C)		 6fbt LYTIC MUREIN
TRANSGLYCOSYLASE
(Pseudomonas
aeruginosa) 		3 / 3 ALA A 188
VAL A 155
TRP A 153
 None
 0.78A 1jo4B-6fbtA:
undetectable		 1jo4B-6fbtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PCG_B_ESTB2_1
(ESTROGEN RECEPTOR)		 6fbt LYTIC MUREIN
TRANSGLYCOSYLASE
(Pseudomonas
aeruginosa) 		5 / 10 ALA A 293
LEU A 316
LEU A 317
ARG A 322
LEU A 283
 None
 1.44A 1pcgB-6fbtA:
undetectable		 1pcgB-6fbtA:
16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UKB_A_BEZA1301_0
(2-HYDROXY-6-OXO-7-ME
THYLOCTA-2,4-DIENOAT
E HYDROLASE)		 6fbt LYTIC MUREIN
TRANSGLYCOSYLASE
(Pseudomonas
aeruginosa) 		4 / 6 ARG A 319
LEU A 571
ALA A 574
LEU A 587
 None
 0.91A 1ukbA-6fbtA:
undetectable		 1ukbA-6fbtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOF_C_FRDC305_2
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 6fbt LYTIC MUREIN
TRANSGLYCOSYLASE
(Pseudomonas
aeruginosa) 		4 / 5 LEU A 260
ASP A 261
PRO A 253
ALA A 256
 None
 0.98A 2aofB-6fbtA:
undetectable		 2aofB-6fbtA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA503_0
(CHORISMATE SYNTHASE)		 6fbt LYTIC MUREIN
TRANSGLYCOSYLASE
(Pseudomonas
aeruginosa) 		4 / 5 GLN A 347
THR A 330
ARG A 331
ALA A 328
 None
 1.14A 2qhfA-6fbtA:
undetectable		 2qhfA-6fbtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WLJ_A_SPMA1303_1
(POTASSIUM CHANNEL)		 6fbt LYTIC MUREIN
TRANSGLYCOSYLASE
(Pseudomonas
aeruginosa) 		3 / 3 ARG A 426
ARG A 459
PRO A 456
 None
 1.02A 2wljA-6fbtA:
undetectable		 2wljA-6fbtA:
13.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2N_B_X2NB1479_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 6fbt LYTIC MUREIN
TRANSGLYCOSYLASE
(Pseudomonas
aeruginosa) 		5 / 12 PHE A 115
TYR A 119
ALA A 143
ALA A 162
LEU A 152
 None
 1.21A 2x2nB-6fbtA:
undetectable		 2x2nB-6fbtA:
11.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_C_ZMRC1776_1
(NEURAMINIDASE A)		 6fbt LYTIC MUREIN
TRANSGLYCOSYLASE
(Pseudomonas
aeruginosa) 		5 / 12 ARG A 438
ILE A 442
ASP A 439
ARG A 392
TYR A 466
 None
 1.26A 2ya7C-6fbtA:
undetectable		 2ya7C-6fbtA:
10.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_D_ZMRD1776_1
(NEURAMINIDASE A)		 6fbt LYTIC MUREIN
TRANSGLYCOSYLASE
(Pseudomonas
aeruginosa) 		5 / 12 ARG A 438
ILE A 442
ASP A 439
ARG A 392
TYR A 466
 None
 1.21A 2ya7D-6fbtA:
undetectable		 2ya7D-6fbtA:
10.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZT7_A_GLYA1300_0
(GLYCYL-TRNA
SYNTHETASE)		 6fbt LYTIC MUREIN
TRANSGLYCOSYLASE
(Pseudomonas
aeruginosa) 		4 / 7 GLU A  81
ARG A  84
ARG A  73
GLU A  69
 None
 1.12A 2zt7A-6fbtA:
2.3		 2zt7A-6fbtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_G_SVRG506_1
(PHOSPHOLIPASE A2)		 6fbt LYTIC MUREIN
TRANSGLYCOSYLASE
(Pseudomonas
aeruginosa) 		4 / 8 VAL A 240
VAL A 241
GLY A 244
LYS A 274
 None
 0.70A 3bjwA-6fbtA:
1.7		 3bjwA-6fbtA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL0_A_1UNA201_2
(PROTEASE)		 6fbt LYTIC MUREIN
TRANSGLYCOSYLASE
(Pseudomonas
aeruginosa) 		5 / 9 LEU A 470
VAL A 619
ILE A 631
GLY A 376
ILE A 620
 None
 0.98A 3el0B-6fbtA:
undetectable		 3el0B-6fbtA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWS_X_T3X500_1
(THYROID HORMONE
RECEPTOR BETA)		 6fbt LYTIC MUREIN
TRANSGLYCOSYLASE
(Pseudomonas
aeruginosa) 		5 / 12 ILE A 442
ILE A 461
ALA A 445
ALA A 433
LEU A 441
 None
 0.98A 3gwsX-6fbtA:
undetectable		 3gwsX-6fbtA:
14.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_A_SAMA301_0
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 6fbt LYTIC MUREIN
TRANSGLYCOSYLASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A 518
ASP A 548
ILE A 551
THR A 481
LEU A 519
 None
 1.27A 3iv6A-6fbtA:
undetectable		 3iv6A-6fbtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LD6_B_KKKB602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 6fbt LYTIC MUREIN
TRANSGLYCOSYLASE
(Pseudomonas
aeruginosa) 		5 / 12 PHE A 289
TRP A 312
ALA A 276
ILE A 281
MET A 297
 None
 1.47A 3ld6B-6fbtA:
undetectable		 3ld6B-6fbtA:
10.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M6V_A_SAMA465_0
(RRNA METHYLASE)		 6fbt LYTIC MUREIN
TRANSGLYCOSYLASE
(Pseudomonas
aeruginosa) 		5 / 12 ALA A 162
GLY A 168
ASP A 129
ASP A 164
PRO A 160
 None
None
None
PO4  A 701 (-3.0A)
None
 1.05A 3m6vA-6fbtA:
undetectable		 3m6vA-6fbtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M6V_B_SAMB465_0
(RRNA METHYLASE)		 6fbt LYTIC MUREIN
TRANSGLYCOSYLASE
(Pseudomonas
aeruginosa) 		5 / 12 ALA A 162
GLY A 168
ASP A 129
ASP A 164
PRO A 160
 None
None
None
PO4  A 701 (-3.0A)
None
 1.08A 3m6vB-6fbtA:
undetectable		 3m6vB-6fbtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBG_A_ACTA207_0
(FAD-LINKED
SULFHYDRYL OXIDASE
ALR)		 6fbt LYTIC MUREIN
TRANSGLYCOSYLASE
(Pseudomonas
aeruginosa) 		4 / 7 LEU A 131
ASP A 108
ARG A 104
ALA A 107
 None
 1.08A 3mbgA-6fbtA:
undetectable
3mbgB-6fbtA:
undetectable		 3mbgA-6fbtA:
undetectable
3mbgB-6fbtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UUD_B_ESTB600_1
(ESTROGEN RECEPTOR)		 6fbt LYTIC MUREIN
TRANSGLYCOSYLASE
(Pseudomonas
aeruginosa) 		5 / 10 ALA A 293
LEU A 316
LEU A 317
ARG A 322
LEU A 283
 None
 1.45A 3uudB-6fbtA:
undetectable		 3uudB-6fbtA:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BBO_B_ACTB1114_0
(BLR5658 PROTEIN)		 6fbt LYTIC MUREIN
TRANSGLYCOSYLASE
(Pseudomonas
aeruginosa) 		3 / 3 TRP A 586
TRP A 598
THR A 601
 None
 1.39A 4bboB-6fbtA:
undetectable		 4bboB-6fbtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7H_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE OXYGENASE)		 6fbt LYTIC MUREIN
TRANSGLYCOSYLASE
(Pseudomonas
aeruginosa) 		3 / 3 ARG A 608
THR A 340
TRP A 343
 None
 1.07A 4d7hA-6fbtA:
undetectable		 4d7hA-6fbtA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QN9_B_DXCB610_0
(N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D)		 6fbt LYTIC MUREIN
TRANSGLYCOSYLASE
(Pseudomonas
aeruginosa) 		3 / 3 GLY A 525
PRO A 524
ALA A 516
 None
 0.52A 4qn9B-6fbtA:
undetectable		 4qn9B-6fbtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UG5_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE OXYGENASE)		 6fbt LYTIC MUREIN
TRANSGLYCOSYLASE
(Pseudomonas
aeruginosa) 		3 / 3 ARG A 608
THR A 340
TRP A 343
 None
 1.15A 4ug5A-6fbtA:
undetectable		 4ug5A-6fbtA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UGL_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE)		 6fbt LYTIC MUREIN
TRANSGLYCOSYLASE
(Pseudomonas
aeruginosa) 		3 / 3 ARG A 608
THR A 340
TRP A 343
 None
 1.03A 4uglA-6fbtA:
undetectable		 4uglA-6fbtA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZME_B_ADNB902_1
(MYOSIN HEAVY CHAIN
KINASE A)		 6fbt LYTIC MUREIN
TRANSGLYCOSYLASE
(Pseudomonas
aeruginosa) 		5 / 10 PHE A 269
VAL A 241
LEU A 245
LEU A 259
THR A 227
 None
 1.35A 4zmeB-6fbtA:
undetectable		 4zmeB-6fbtA:
13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXE_B_ESTB1000_1
(ESTROGEN RECEPTOR)		 6fbt LYTIC MUREIN
TRANSGLYCOSYLASE
(Pseudomonas
aeruginosa) 		5 / 10 ALA A 293
LEU A 316
LEU A 317
ARG A 322
LEU A 283
 None
 1.48A 5dxeB-6fbtA:
undetectable		 5dxeB-6fbtA:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_A_PZAA1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		 6fbt LYTIC MUREIN
TRANSGLYCOSYLASE
(Pseudomonas
aeruginosa) 		4 / 7 VAL A 217
SER A 216
GLY A 211
VAL A 240
 None
 0.79A 5fpdA-6fbtA:
undetectable		 5fpdA-6fbtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6C_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE OXYGENASE)		 6fbt LYTIC MUREIN
TRANSGLYCOSYLASE
(Pseudomonas
aeruginosa) 		3 / 3 ARG A 608
THR A 340
TRP A 343
 None
 1.07A 5g6cA-6fbtA:
undetectable		 5g6cA-6fbtA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HYR_A_ESTA601_1
(ESTROGEN RECEPTOR)		 6fbt LYTIC MUREIN
TRANSGLYCOSYLASE
(Pseudomonas
aeruginosa) 		5 / 10 ALA A 293
LEU A 316
LEU A 317
ARG A 322
LEU A 283
 None
 1.48A 5hyrA-6fbtA:
undetectable		 5hyrA-6fbtA:
15.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HYR_B_ESTB601_1
(ESTROGEN RECEPTOR)		 6fbt LYTIC MUREIN
TRANSGLYCOSYLASE
(Pseudomonas
aeruginosa) 		5 / 11 ALA A 293
LEU A 316
LEU A 317
ARG A 322
LEU A 283
 None
 1.47A 5hyrB-6fbtA:
undetectable		 5hyrB-6fbtA:
15.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_A_CVIA301_0
(REGULATORY PROTEIN
TETR)		 6fbt LYTIC MUREIN
TRANSGLYCOSYLASE
(Pseudomonas
aeruginosa) 		5 / 12 ALA A 448
GLU A 440
LEU A 401
ILE A 396
ASP A 437
 None
 1.19A 5vlmA-6fbtA:
undetectable		 5vlmA-6fbtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WGD_A_ESTA601_1
(ESTROGEN RECEPTOR)		 6fbt LYTIC MUREIN
TRANSGLYCOSYLASE
(Pseudomonas
aeruginosa) 		5 / 9 ALA A 293
LEU A 316
LEU A 317
ARG A 322
LEU A 283
 None
 1.49A 5wgdA-6fbtA:
undetectable		 5wgdA-6fbtA:
25.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WGQ_B_ESTB601_1
(ESTROGEN RECEPTOR)		 6fbt LYTIC MUREIN
TRANSGLYCOSYLASE
(Pseudomonas
aeruginosa) 		5 / 10 ALA A 293
LEU A 316
LEU A 317
ARG A 322
LEU A 283
 None
 1.48A 5wgqB-6fbtA:
undetectable		 5wgqB-6fbtA:
25.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_A_SAMA902_1
(MRNA CAPPING ENZYME
P5)		 6fbt LYTIC MUREIN
TRANSGLYCOSYLASE
(Pseudomonas
aeruginosa) 		3 / 3 TYR A 345
ASP A 381
ASP A 596
 None
 0.80A 5x6yA-6fbtA:
undetectable		 5x6yA-6fbtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6I0Y_A_TRPA3001_0
(23S RIBOSOMAL RNA
TRYPTOPHANASE OPERON
LEADER PEPTIDE)		 6fbt LYTIC MUREIN
TRANSGLYCOSYLASE
(Pseudomonas
aeruginosa) 		3 / 3 TRP A 346
ILE A 599
ASP A 596
 None
 0.90A 6i0y7-6fbtA:
undetectable		 6i0y7-6fbtA:
undetectable