SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6fd5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6N_A_T1CA392_1
(TETX2 PROTEIN)
6fd5 -
(-)
5 / 11 PHE A  71
GLY A  68
ALA A  41
GLY A  44
GLU A   5
None
1.33A 4a6nA-6fd5A:
undetectable
4a6nA-6fd5A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IL1_A_SAMA601_0
(METTL3)
6fd5 -
(-)
5 / 12 ASP A  65
ILE A  86
ARG A  87
LEU A  92
GLU A 141
None
1.01A 5il1A-6fd5A:
undetectable
5il1A-6fd5A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K7U_A_SAMA601_0
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)
6fd5 -
(-)
5 / 12 ASP A  65
ILE A  86
ARG A  87
LEU A  92
GLU A 141
None
1.04A 5k7uA-6fd5A:
2.2
5k7uA-6fd5A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH8_A_ACTA302_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)
6fd5 -
(-)
3 / 3 CYH A 153
MET A 136
ASN A 137
None
1.15A 5qh8A-6fd5A:
undetectable
5qh8A-6fd5A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA303_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)
6fd5 -
(-)
3 / 3 GLU A 180
TYR A 179
ARG A  27
None
0.87A 5uunA-6fd5A:
undetectable
5uunA-6fd5A:
undetectable