SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6fd7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VM1_A_TAZA504_1
(BETA-LACTAMASE SHV-1)
6fd7 -
(-)
3 / 3 ASP A 223
TYR A 204
GLU A 229
None
0.81A 1vm1A-6fd7A:
undetectable
1vm1A-6fd7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROD_D_NCAD302_0
(NICOTINAMIDE
N-METHYLTRANSFERASE)
6fd7 -
(-)
4 / 7 LEU A 136
ASP A 154
ALA A 152
TYR A 156
None
1.17A 3rodD-6fd7A:
undetectable
3rodD-6fd7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YV5_A_SVRA205_2
(BASIC PHOSPHOLIPASE
A2 HOMOLOG 2)
6fd7 -
(-)
4 / 6 LEU A 196
ASN A 166
PRO A 167
ARG A 226
None
1.44A 4yv5B-6fd7A:
undetectable
4yv5B-6fd7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZV2_B_LEVB801_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1)
6fd7 -
(-)
3 / 3 TYR A 143
LEU A 136
ASP A 161
None
0.87A 5zv2B-6fd7A:
undetectable
5zv2B-6fd7A:
undetectable