SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6fdg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1352_1
(PROSTAGLANDIN
REDUCTASE 2)		 6fdg 4-HYDROXYBENZOYL-COA
THIOESTERASE
(Staphylococcus
aureus) 		4 / 7 TYR A  45
TYR A  90
LEU A  35
TYR A 133
 None
 1.44A 2w98A-6fdgA:
undetectable
2w98B-6fdgA:
undetectable		 2w98A-6fdgA:
15.05
2w98B-6fdgA:
15.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_B_HSMB1160_1
(ALLERGEN ARG R 1)		 6fdg 4-HYDROXYBENZOYL-COA
THIOESTERASE
(Staphylococcus
aureus) 		4 / 7 TYR A  83
VAL A  80
TYR A  90
ILE A  38
 None
 0.96A 2x45B-6fdgA:
undetectable		 2x45B-6fdgA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_C_HSMC1160_1
(ALLERGEN ARG R 1)		 6fdg 4-HYDROXYBENZOYL-COA
THIOESTERASE
(Staphylococcus
aureus) 		4 / 7 TYR A  83
VAL A  80
TYR A  90
ILE A  38
 None
 0.97A 2x45C-6fdgA:
undetectable		 2x45C-6fdgA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A27_A_SAMA250_1
(UNCHARACTERIZED
PROTEIN MJ1557)		 6fdg 4-HYDROXYBENZOYL-COA
THIOESTERASE
(Staphylococcus
aureus) 		3 / 3 MET A   1
GLU A  93
ASN A  63
 None
 1.03A 3a27A-6fdgA:
undetectable		 3a27A-6fdgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK3_A_0LIA1_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 6fdg 4-HYDROXYBENZOYL-COA
THIOESTERASE
(Staphylococcus
aureus) 		4 / 7 LEU A  41
VAL A  74
ILE A   5
ARG A  11
 None
 1.28A 3ik3A-6fdgA:
undetectable		 3ik3A-6fdgA:
14.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK3_B_0LIB2_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 6fdg 4-HYDROXYBENZOYL-COA
THIOESTERASE
(Staphylococcus
aureus) 		4 / 7 LEU A  41
VAL A  74
ILE A   5
ARG A  11
 None
 1.22A 3ik3B-6fdgA:
undetectable		 3ik3B-6fdgA:
14.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROD_C_NCAC302_0
(NICOTINAMIDE
N-METHYLTRANSFERASE)		 6fdg 4-HYDROXYBENZOYL-COA
THIOESTERASE
(Staphylococcus
aureus) 		5 / 10 ASP A  36
ALA A  33
TYR A  37
SER A   4
TYR A  92
 None
 1.45A 3rodC-6fdgA:
undetectable		 3rodC-6fdgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROD_C_NCAC302_0
(NICOTINAMIDE
N-METHYLTRANSFERASE)		 6fdg 4-HYDROXYBENZOYL-COA
THIOESTERASE
(Staphylococcus
aureus) 		5 / 10 TYR A 133
ASP A  36
ALA A  33
TYR A  37
SER A   4
 None
 1.36A 3rodC-6fdgA:
undetectable		 3rodC-6fdgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JHD_E_EDTE301_0
(BETA-2-MICROGLOBULIN
TCRBETA CHAIN)		 6fdg 4-HYDROXYBENZOYL-COA
THIOESTERASE
(Staphylococcus
aureus) 		4 / 8 SER A   4
THR A   6
ARG A  34
ILE A  38
 None
 1.11A 5jhdE-6fdgA:
undetectable
5jhdG-6fdgA:
undetectable		 5jhdE-6fdgA:
undetectable
5jhdG-6fdgA:
undetectable