SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6fdt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F3T_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 6fdt -
(-) 		4 / 6 TYR A 349
LYS A 351
LEU A 379
GLU A 380
 None
 0.99A 4f3tA-6fdtA:
undetectable		 4f3tA-6fdtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 6fdt -
(-) 		4 / 6 TYR A 349
LYS A 351
LEU A 379
GLU A 380
 None
 0.94A 4z4cA-6fdtA:
undetectable		 4z4cA-6fdtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4D_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 6fdt -
(-) 		4 / 5 TYR A 349
LYS A 351
LEU A 379
GLU A 380
 None
 0.93A 4z4dA-6fdtA:
undetectable		 4z4dA-6fdtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4F_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 6fdt -
(-) 		4 / 7 TYR A 349
LYS A 351
LEU A 379
GLU A 380
 None
 0.95A 4z4fA-6fdtA:
undetectable		 4z4fA-6fdtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4H_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 6fdt -
(-) 		4 / 5 TYR A 349
LYS A 351
LEU A 379
GLU A 380
 None
 0.98A 4z4hA-6fdtA:
undetectable		 4z4hA-6fdtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CVT_B_ACTB200_0
(N5-CARBOXYAMINOIMIDA
ZOLE RIBONUCLEOTIDE
MUTASE)		 6fdt -
(-) 		3 / 3 ASN A 321
ALA A 320
ARG A 355
 None
 0.70A 5cvtB-6fdtA:
undetectable		 5cvtB-6fdtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JS1_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 6fdt -
(-) 		4 / 5 TYR A 349
LYS A 351
LEU A 379
GLU A 380
 None
 1.08A 5js1A-6fdtA:
undetectable		 5js1A-6fdtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WEA_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 6fdt -
(-) 		4 / 5 TYR A 349
LYS A 351
LEU A 379
GLU A 380
 None
 1.17A 5weaA-6fdtA:
undetectable		 5weaA-6fdtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CBD_A_TRPA901_0
(PROTEIN ARGONAUTE-2)		 6fdt -
(-) 		4 / 5 TYR A 349
LYS A 351
LEU A 379
GLU A 380
 None
 0.90A 6cbdA-6fdtA:
undetectable		 6cbdA-6fdtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MA7_A_TPFA602_0
(CYTOCHROME P450 3A4)		 6fdt -
(-) 		4 / 7 ARG A 356
ALA A 354
ILE A 343
ALA A 342
 None
 0.94A 6ma7A-6fdtA:
undetectable		 6ma7A-6fdtA:
undetectable