SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6fe4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T7I_A_017A200_2
(POL POLYPROTEIN)		 6fe4 NB113
(Vicugna
pacos) 		4 / 7 ASP F  62
VAL F  64
GLY F  50
ILE F  51
 None
 0.81A 1t7iB-6fe4F:
undetectable		 1t7iB-6fe4F:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T7J_A_478A200_2
(POL POLYPROTEIN)		 6fe4 NB113
(Vicugna
pacos) 		4 / 7 ASP F  62
VAL F  64
GLY F  50
ILE F  51
 None
 0.84A 1t7jB-6fe4F:
undetectable		 1t7jB-6fe4F:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 6fe4 NB113
(Vicugna
pacos) 		6 / 11 PHE F  29
ASN F  74
GLY F  55
THR F  58
ILE F  70
LEU F  79
 None
 1.46A 1z11A-6fe4F:
undetectable		 1z11A-6fe4F:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXV_C_MTXC2000_1
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 6fe4 NB113
(Vicugna
pacos) 		5 / 11 VAL F   2
ALA F  24
MET F  34
ARG F  72
ASN F  74
 None
 0.81A 3qxvC-6fe4F:
20.8		 3qxvC-6fe4F:
66.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_A_1GNA607_1
(PHIAB6 TAILSPIKE)		 6fe4 NB113
(Vicugna
pacos) 		3 / 3 THR F  28
SER F  31
TYR F  32
 None
 0.86A 5jsdA-6fe4F:
undetectable		 5jsdA-6fe4F:
7.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB618_1
(PHIAB6 TAILSPIKE)		 6fe4 NB113
(Vicugna
pacos) 		3 / 3 THR F  28
SER F  31
TYR F  32
 None
 0.87A 5jsdB-6fe4F:
undetectable		 5jsdB-6fe4F:
7.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_C_1GNC608_1
(PHIAB6 TAILSPIKE)		 6fe4 NB113
(Vicugna
pacos) 		3 / 3 THR F  28
SER F  31
TYR F  32
 None
 0.86A 5jsdC-6fe4F:
undetectable		 5jsdC-6fe4F:
7.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_A_1GNA608_1
(PHIAB6 TAILSPIKE)		 6fe4 NB113
(Vicugna
pacos) 		3 / 3 THR F  28
SER F  31
TYR F  32
 None
 0.88A 5jseA-6fe4F:
undetectable		 5jseA-6fe4F:
7.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_B_1GNB611_1
(PHIAB6 TAILSPIKE)		 6fe4 NB113
(Vicugna
pacos) 		3 / 3 THR F  28
SER F  31
TYR F  32
 None
 0.88A 5jseB-6fe4F:
undetectable		 5jseB-6fe4F:
7.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_C_1GNC611_1
(PHIAB6 TAILSPIKE)		 6fe4 NB113
(Vicugna
pacos) 		3 / 3 THR F  28
SER F  31
TYR F  32
 None
 0.87A 5jseC-6fe4F:
2.8		 5jseC-6fe4F:
7.60