SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6fej'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_B_VIBB503_1
(YKOF)		 6fej ALL4940 PROTEIN
(Nostoc
sp.
PCC
7120) 		4 / 7 PHE A  43
ILE A  19
ILE A  24
THR A 123
 None
URE  A 201 (-3.6A)
None
None
 0.76A 1sbrB-6fejA:
undetectable		 1sbrB-6fejA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LS4_H_TCIH220_1
(HEAVY CHAIN OF
ANTIBODY FAB
FRAGMENT)		 6fej ALL4940 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 10 VAL A  95
VAL A  93
TYR A  27
GLY A  81
GLY A  18
 None
None
URE  A 202 (-4.7A)
None
None
 1.14A 3ls4H-6fejA:
undetectable		 3ls4H-6fejA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E72_A_SAMA400_0
(N2,
N2-DIMETHYLGUANOSINE
TRNA
METHYLTRANSFERASE)		 6fej ALL4940 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 12 ILE A  57
PHE A  53
ALA A 136
PRO A  52
LEU A 127
 None
 0.81A 5e72A-6fejA:
undetectable		 5e72A-6fejA:
undetectable