SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6fel'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4G_B_ZMRB466_1
(NEURAMINIDASE)		 6fel 14-3-3 PROTEIN GAMMA
(Homo
sapiens) 		5 / 12 ARG A  61
GLU A 185
ARG A 132
ASN A 178
ARG A  57
 None
 1.20A 1a4gB-6felA:
undetectable		 1a4gB-6felA:
10.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NNC_A_ZMRA479_1
(NEURAMINIDASE N9)		 6fel 14-3-3 PROTEIN GAMMA
(Homo
sapiens) 		5 / 12 ARG A  61
GLU A 185
ARG A 132
ASN A 178
ARG A  57
 None
 1.11A 1nncA-6felA:
undetectable		 1nncA-6felA:
11.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_A_ZMRA1477_1
(NEURAMINIDASE)		 6fel 14-3-3 PROTEIN GAMMA
(Homo
sapiens) 		5 / 12 ARG A  61
GLU A 185
ARG A 132
ASN A 178
ARG A  57
 None
 1.13A 2cmlA-6felA:
undetectable		 2cmlA-6felA:
11.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_B_ZMRB2477_1
(NEURAMINIDASE)		 6fel 14-3-3 PROTEIN GAMMA
(Homo
sapiens) 		5 / 12 ARG A  61
GLU A 185
ARG A 132
ASN A 178
ARG A  57
 None
 1.11A 2cmlB-6felA:
undetectable		 2cmlB-6felA:
11.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_C_ZMRC3477_1
(NEURAMINIDASE)		 6fel 14-3-3 PROTEIN GAMMA
(Homo
sapiens) 		5 / 12 ARG A  61
GLU A 185
ARG A 132
ASN A 178
ARG A  57
 None
 1.12A 2cmlC-6felA:
undetectable		 2cmlC-6felA:
11.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_D_ZMRD4477_1
(NEURAMINIDASE)		 6fel 14-3-3 PROTEIN GAMMA
(Homo
sapiens) 		5 / 12 ARG A  61
GLU A 185
ARG A 132
ASN A 178
ARG A  57
 None
 1.15A 2cmlD-6felA:
undetectable		 2cmlD-6felA:
11.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VUF_A_FUAA2002_1
(SERUM ALBUMIN)		 6fel 14-3-3 PROTEIN GAMMA
(Homo
sapiens) 		4 / 9 ILE A 186
ALA A 144
VAL A 147
GLU A 148
 None
 0.51A 2vufA-6felA:
3.5		 2vufA-6felA:
11.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CKZ_A_ZMRA469_1
(NEURAMINIDASE)		 6fel 14-3-3 PROTEIN GAMMA
(Homo
sapiens) 		5 / 12 ARG A  61
GLU A 185
ARG A 132
ASN A 178
ARG A  57
 None
 1.17A 3ckzA-6felA:
undetectable		 3ckzA-6felA:
11.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SAN_A_ZMRA901_1
(NEURAMINIDASE)		 6fel 14-3-3 PROTEIN GAMMA
(Homo
sapiens) 		5 / 12 ARG A  61
GLU A 185
ARG A 132
ASN A 178
ARG A  57
 None
 1.18A 3sanA-6felA:
undetectable		 3sanA-6felA:
13.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SAN_B_ZMRB901_1
(NEURAMINIDASE)		 6fel 14-3-3 PROTEIN GAMMA
(Homo
sapiens) 		5 / 12 ARG A  61
GLU A 185
ARG A 132
ASN A 178
ARG A  57
 None
 1.17A 3sanB-6felA:
undetectable		 3sanB-6felA:
13.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFU_C_RBVC601_1
(RNA POLYMERASE)		 6fel 14-3-3 PROTEIN GAMMA
(Homo
sapiens) 		5 / 11 ARG A  57
LEU A  93
LEU A 101
GLY A 128
ASP A 129
 None
 1.30A 3sfuC-6felA:
undetectable		 3sfuC-6felA:
9.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TI5_A_ZMRA1002_1
(NEURAMINIDASE)		 6fel 14-3-3 PROTEIN GAMMA
(Homo
sapiens) 		5 / 12 ARG A  61
GLU A 185
ARG A 132
ASN A 178
ARG A  57
 None
 1.18A 3ti5A-6felA:
undetectable		 3ti5A-6felA:
11.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TI5_B_ZMRB1002_1
(NEURAMINIDASE)		 6fel 14-3-3 PROTEIN GAMMA
(Homo
sapiens) 		5 / 12 ARG A  61
GLU A 185
ARG A 132
ASN A 178
ARG A  57
 None
 1.17A 3ti5B-6felA:
undetectable		 3ti5B-6felA:
11.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TIC_A_ZMRA1002_1
(NEURAMINIDASE)		 6fel 14-3-3 PROTEIN GAMMA
(Homo
sapiens) 		5 / 12 ARG A  61
GLU A 185
ARG A 132
ASN A 178
ARG A  57
 None
 1.12A 3ticA-6felA:
undetectable		 3ticA-6felA:
10.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TIC_B_ZMRB1002_1
(NEURAMINIDASE)		 6fel 14-3-3 PROTEIN GAMMA
(Homo
sapiens) 		5 / 12 ARG A  61
GLU A 185
ARG A 132
ASN A 178
ARG A  57
 None
 1.13A 3ticB-6felA:
undetectable		 3ticB-6felA:
10.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TIC_C_ZMRC1002_1
(NEURAMINIDASE)		 6fel 14-3-3 PROTEIN GAMMA
(Homo
sapiens) 		5 / 12 ARG A  61
GLU A 185
ARG A 132
ASN A 178
ARG A  57
 None
 1.13A 3ticC-6felA:
undetectable		 3ticC-6felA:
10.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TIC_D_ZMRD1002_1
(NEURAMINIDASE)		 6fel 14-3-3 PROTEIN GAMMA
(Homo
sapiens) 		5 / 12 ARG A  61
GLU A 185
ARG A 132
ASN A 178
ARG A  57
 None
 1.13A 3ticD-6felA:
undetectable		 3ticD-6felA:
10.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_D_SAMD401_0
(MNMC2)		 6fel 14-3-3 PROTEIN GAMMA
(Homo
sapiens) 		5 / 12 TYR A 183
GLY A 128
ALA A 157
PHE A 182
LEU A 175
 None
 1.17A 3vywD-6felA:
undetectable		 3vywD-6felA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7N_A_ZMRA601_1
(NEURAMINIDASE)		 6fel 14-3-3 PROTEIN GAMMA
(Homo
sapiens) 		5 / 12 ARG A  61
GLU A 185
ARG A 132
ASN A 178
ARG A  57
 None
 1.14A 4b7nA-6felA:
undetectable		 4b7nA-6felA:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPN_A_ZMRA700_1
(NEURAMINIDASE)		 6fel 14-3-3 PROTEIN GAMMA
(Homo
sapiens) 		5 / 12 ARG A  61
GLU A 185
ARG A 132
ASN A 178
ARG A  57
 None
 1.24A 4cpnA-6felA:
undetectable		 4cpnA-6felA:
10.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_A_ZMRA1471_1
(NEURAMINIDASE)		 6fel 14-3-3 PROTEIN GAMMA
(Homo
sapiens) 		5 / 12 ARG A  61
GLU A 185
ARG A 132
ASN A 178
ARG A  57
 None
 1.17A 4cpzA-6felA:
undetectable		 4cpzA-6felA:
10.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_B_ZMRB1471_1
(NEURAMINIDASE)		 6fel 14-3-3 PROTEIN GAMMA
(Homo
sapiens) 		5 / 12 ARG A  61
GLU A 185
ARG A 132
ASN A 178
ARG A  57
 None
 1.17A 4cpzB-6felA:
undetectable		 4cpzB-6felA:
10.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_C_ZMRC1470_1
(NEURAMINIDASE)		 6fel 14-3-3 PROTEIN GAMMA
(Homo
sapiens) 		5 / 12 ARG A  61
GLU A 185
ARG A 132
ASN A 178
ARG A  57
 None
 1.19A 4cpzC-6felA:
undetectable		 4cpzC-6felA:
10.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWR_A_ZMRA513_1
(NEURAMINIDASE)		 6fel 14-3-3 PROTEIN GAMMA
(Homo
sapiens) 		5 / 12 ARG A  61
GLU A 185
ARG A 132
ASN A 178
ARG A  57
 None
 1.13A 4mwrA-6felA:
undetectable		 4mwrA-6felA:
10.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWV_A_BCZA513_1
(NEURAMINIDASE)		 6fel 14-3-3 PROTEIN GAMMA
(Homo
sapiens) 		3 / 3 ARG A  61
GLU A 185
ARG A  57
 None
 0.97A 4mwvA-6felA:
undetectable		 4mwvA-6felA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WA5_A_ZMRA501_1
(NEURAMINIDASE)		 6fel 14-3-3 PROTEIN GAMMA
(Homo
sapiens) 		5 / 12 ARG A  61
GLU A 185
ARG A 132
ASN A 178
ARG A  57
 None
 1.14A 4wa5A-6felA:
undetectable		 4wa5A-6felA:
12.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 6fel 14-3-3 PROTEIN GAMMA
(Homo
sapiens) 		5 / 9 SER A 161
ALA A 157
ALA A 153
GLY A 174
ASP A 129
 None
 1.08A 5d0xK-6felA:
undetectable
5d0xL-6felA:
undetectable		 5d0xK-6felA:
16.26
5d0xL-6felA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 6fel 14-3-3 PROTEIN GAMMA
(Homo
sapiens) 		5 / 9 SER A 161
ALA A 157
ALA A 153
GLY A 174
ASP A 129
 None
 1.05A 5d0xY-6felA:
undetectable
5d0xZ-6felA:
undetectable		 5d0xY-6felA:
16.26
5d0xZ-6felA:
22.29