SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6ffj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2R_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		 6ffj -
(-) 		4 / 4 HIS A 454
GLU A  99
HIS A  35
LEU A  45
 None
 1.33A 4m2rA-6ffjA:
undetectable		 4m2rA-6ffjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M7K_H_ACTH302_0
(10H10 HEAVY CHAIN)		 6ffj -
(-) 		4 / 5 VAL A   2
TYR A  27
ARG A  98
TYR A 114
 None
 0.38A 4m7kH-6ffjA:
21.6		 4m7kH-6ffjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UIL_H_QI9H1223_0
(FAB 314.1)		 6ffj -
(-) 		6 / 12 HIS A  35
GLN A 488
GLN A 489
GLY A 490
LEU A 493
PRO A 495
 None
 0.77A 4uilH-6ffjA:
21.4
4uilL-6ffjA:
20.7		 4uilH-6ffjA:
undetectable
4uilL-6ffjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UIN_H_QI9H1226_0
(FAB 314.3)		 6ffj -
(-) 		5 / 12 HIS A  35
TRP A  47
GLU A  99
GLY A 490
PRO A 495
 None
 1.03A 4uinH-6ffjA:
21.9
4uinL-6ffjA:
20.7		 4uinH-6ffjA:
undetectable
4uinL-6ffjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UIN_H_QI9H1226_0
(FAB 314.3)		 6ffj -
(-) 		5 / 12 HIS A  35
TRP A  47
GLY A 490
LEU A 493
PRO A 495
 None
 0.77A 4uinH-6ffjA:
21.9
4uinL-6ffjA:
20.7		 4uinH-6ffjA:
undetectable
4uinL-6ffjA:
undetectable