SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6ffl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N4F_A_ASRA141_0
(LYSOZYME C)		 6ffl MALTOSE/MALTODEXTRIN
TRANSPORT PERMEASE
HOMOLOGUE
(Bdellovibrio
bacteriovorus) 		4 / 6 ASP A 182
GLY A 183
THR A 185
PRO A 186
 None
 0.68A 1n4fA-6fflA:
undetectable		 1n4fA-6fflA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T85_A_CAMA422_0
(CYTOCHROME P450-CAM)		 6ffl MALTOSE/MALTODEXTRIN
TRANSPORT PERMEASE
HOMOLOGUE
(Bdellovibrio
bacteriovorus) 		4 / 7 PHE A  90
TYR A  89
THR A 295
LEU A 291
 None
 1.03A 1t85A-6fflA:
undetectable		 1t85A-6fflA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T87_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 6ffl MALTOSE/MALTODEXTRIN
TRANSPORT PERMEASE
HOMOLOGUE
(Bdellovibrio
bacteriovorus) 		4 / 7 PHE A  90
TYR A  89
THR A 295
LEU A 291
 None
 1.06A 1t87A-6fflA:
undetectable		 1t87A-6fflA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FEU_A_CAMA1420_0
(CYTOCHROME P450-CAM)		 6ffl MALTOSE/MALTODEXTRIN
TRANSPORT PERMEASE
HOMOLOGUE
(Bdellovibrio
bacteriovorus) 		4 / 6 PHE A  90
TYR A  89
THR A 295
LEU A 291
 None
 1.01A 2feuA-6fflA:
undetectable		 2feuA-6fflA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FEU_B_CAMB1421_0
(CYTOCHROME P450-CAM)		 6ffl MALTOSE/MALTODEXTRIN
TRANSPORT PERMEASE
HOMOLOGUE
(Bdellovibrio
bacteriovorus) 		4 / 7 PHE A  90
TYR A  89
THR A 295
LEU A 291
 None
 1.01A 2feuB-6fflA:
undetectable		 2feuB-6fflA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QWX_B_ML1B233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 6ffl MALTOSE/MALTODEXTRIN
TRANSPORT PERMEASE
HOMOLOGUE
(Bdellovibrio
bacteriovorus) 		4 / 7 GLY A 234
MET A 117
GLY A  14
PHE A 248
 None
 0.81A 2qwxA-6fflA:
undetectable
2qwxB-6fflA:
undetectable		 2qwxA-6fflA:
15.45
2qwxB-6fflA:
15.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R2V_D_ACTD37_0
(GCN4 LEUCINE ZIPPER)		 6ffl MALTOSE/MALTODEXTRIN
TRANSPORT PERMEASE
HOMOLOGUE
(Bdellovibrio
bacteriovorus) 		3 / 3 LYS A 279
ARG A   4
VAL A   3
 None
 1.09A 2r2vC-6fflA:
undetectable
2r2vD-6fflA:
undetectable		 2r2vC-6fflA:
undetectable
2r2vD-6fflA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUH_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 6ffl MALTOSE/MALTODEXTRIN
TRANSPORT PERMEASE
HOMOLOGUE
(Bdellovibrio
bacteriovorus) 		4 / 6 PHE A  90
TYR A  89
THR A 295
LEU A 291
 None
 1.04A 2zuhA-6fflA:
undetectable		 2zuhA-6fflA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUI_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 6ffl MALTOSE/MALTODEXTRIN
TRANSPORT PERMEASE
HOMOLOGUE
(Bdellovibrio
bacteriovorus) 		4 / 6 PHE A  90
TYR A  89
THR A 295
LEU A 291
 None
 1.04A 2zuiA-6fflA:
undetectable		 2zuiA-6fflA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWT_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 6ffl MALTOSE/MALTODEXTRIN
TRANSPORT PERMEASE
HOMOLOGUE
(Bdellovibrio
bacteriovorus) 		4 / 7 PHE A  90
TYR A  89
THR A 295
LEU A 291
 None
 1.04A 2zwtA-6fflA:
undetectable		 2zwtA-6fflA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWU_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 6ffl MALTOSE/MALTODEXTRIN
TRANSPORT PERMEASE
HOMOLOGUE
(Bdellovibrio
bacteriovorus) 		4 / 7 PHE A  90
TYR A  89
THR A 295
LEU A 291
 None
 1.04A 2zwuA-6fflA:
undetectable		 2zwuA-6fflA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCJ_B_THHB401_0
(PROBABLE
5'-PHOSPHORIBOSYLGLY
CINAMIDE
FORMYLTRANSFERASE
PURN)		 6ffl MALTOSE/MALTODEXTRIN
TRANSPORT PERMEASE
HOMOLOGUE
(Bdellovibrio
bacteriovorus) 		4 / 8 LEU A 310
LEU A 328
VAL A 322
GLY A 308
 None
 0.84A 3dcjB-6fflA:
undetectable		 3dcjB-6fflA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 6ffl MALTOSE/MALTODEXTRIN
TRANSPORT PERMEASE
HOMOLOGUE
(Bdellovibrio
bacteriovorus) 		4 / 7 PHE A  90
TYR A  89
THR A 295
LEU A 291
 None
 0.98A 3fwfA-6fflA:
undetectable		 3fwfA-6fflA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_B_CAMB420_0
(CAMPHOR
5-MONOOXYGENASE)		 6ffl MALTOSE/MALTODEXTRIN
TRANSPORT PERMEASE
HOMOLOGUE
(Bdellovibrio
bacteriovorus) 		4 / 7 PHE A  90
TYR A  89
THR A 295
LEU A 291
 None
 0.99A 3fwfB-6fflA:
undetectable		 3fwfB-6fflA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWJ_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 6ffl MALTOSE/MALTODEXTRIN
TRANSPORT PERMEASE
HOMOLOGUE
(Bdellovibrio
bacteriovorus) 		4 / 7 PHE A  90
TYR A  89
THR A 295
LEU A 291
 None
 1.02A 3fwjA-6fflA:
undetectable		 3fwjA-6fflA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L63_A_CAMA440_0
(CAMPHOR
5-MONOOXYGENASE)		 6ffl MALTOSE/MALTODEXTRIN
TRANSPORT PERMEASE
HOMOLOGUE
(Bdellovibrio
bacteriovorus) 		4 / 7 PHE A  90
TYR A  89
THR A 295
LEU A 291
 None
 0.99A 3l63A-6fflA:
undetectable		 3l63A-6fflA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NRR_A_D16A520_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 6ffl MALTOSE/MALTODEXTRIN
TRANSPORT PERMEASE
HOMOLOGUE
(Bdellovibrio
bacteriovorus) 		5 / 12 ALA A 168
LEU A 354
THR A 190
PRO A 368
LEU A 188
 None
 1.22A 3nrrA-6fflA:
undetectable		 3nrrA-6fflA:
10.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NRR_B_D16B520_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 6ffl MALTOSE/MALTODEXTRIN
TRANSPORT PERMEASE
HOMOLOGUE
(Bdellovibrio
bacteriovorus) 		5 / 12 ALA A 168
LEU A 354
THR A 190
PRO A 368
LEU A 188
 None
 1.20A 3nrrB-6fflA:
undetectable		 3nrrB-6fflA:
10.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRH_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 6ffl MALTOSE/MALTODEXTRIN
TRANSPORT PERMEASE
HOMOLOGUE
(Bdellovibrio
bacteriovorus) 		4 / 7 PHE A  90
TYR A  89
THR A 295
LEU A 291
 None
 1.03A 3wrhA-6fflA:
undetectable		 3wrhA-6fflA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRJ_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 6ffl MALTOSE/MALTODEXTRIN
TRANSPORT PERMEASE
HOMOLOGUE
(Bdellovibrio
bacteriovorus) 		4 / 7 PHE A  90
TYR A  89
THR A 295
LEU A 291
 None
 1.01A 3wrjA-6fflA:
undetectable		 3wrjA-6fflA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRL_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 6ffl MALTOSE/MALTODEXTRIN
TRANSPORT PERMEASE
HOMOLOGUE
(Bdellovibrio
bacteriovorus) 		4 / 7 PHE A  90
TYR A  89
THR A 295
LEU A 291
 None
 1.01A 3wrlA-6fflA:
undetectable		 3wrlA-6fflA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRL_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 6ffl MALTOSE/MALTODEXTRIN
TRANSPORT PERMEASE
HOMOLOGUE
(Bdellovibrio
bacteriovorus) 		4 / 7 PHE A  90
TYR A  89
THR A 295
LEU A 291
 None
 1.01A 3wrlE-6fflA:
undetectable		 3wrlE-6fflA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 6ffl MALTOSE/MALTODEXTRIN
TRANSPORT PERMEASE
HOMOLOGUE
(Bdellovibrio
bacteriovorus) 		4 / 7 PHE A  90
TYR A  89
THR A 295
LEU A 291
 None
 1.00A 3wrmA-6fflA:
undetectable		 3wrmA-6fflA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_F_CAMF503_0
(CAMPHOR
5-MONOOXYGENASE)		 6ffl MALTOSE/MALTODEXTRIN
TRANSPORT PERMEASE
HOMOLOGUE
(Bdellovibrio
bacteriovorus) 		4 / 7 PHE A  90
TYR A  89
THR A 295
LEU A 291
 None
 1.01A 3wrmF-6fflA:
undetectable		 3wrmF-6fflA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4G_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 6ffl MALTOSE/MALTODEXTRIN
TRANSPORT PERMEASE
HOMOLOGUE
(Bdellovibrio
bacteriovorus) 		4 / 7 PHE A  90
TYR A  89
THR A 295
LEU A 291
 None
 1.02A 4l4gA-6fflA:
undetectable		 4l4gA-6fflA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_P_BEZP801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 6ffl MALTOSE/MALTODEXTRIN
TRANSPORT PERMEASE
HOMOLOGUE
(Bdellovibrio
bacteriovorus) 		4 / 5 SER A 331
ALA A 332
HIS A 115
LEU A 310
 None
 1.18A 5dzkb-6fflA:
undetectable
5dzkp-6fflA:
undetectable		 5dzkb-6fflA:
undetectable
5dzkp-6fflA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_P_BEZP801_1
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 6ffl MALTOSE/MALTODEXTRIN
TRANSPORT PERMEASE
HOMOLOGUE
(Bdellovibrio
bacteriovorus) 		4 / 6 SER A 331
ALA A 332
HIS A 115
LEU A 310
 None
 1.20A 5dzkB-6fflA:
undetectable
5dzkP-6fflA:
undetectable		 5dzkB-6fflA:
undetectable
5dzkP-6fflA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_Q_BEZQ801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 6ffl MALTOSE/MALTODEXTRIN
TRANSPORT PERMEASE
HOMOLOGUE
(Bdellovibrio
bacteriovorus) 		4 / 5 SER A 331
ALA A 332
HIS A 115
LEU A 310
 None
 1.18A 5dzkc-6fflA:
undetectable
5dzkq-6fflA:
undetectable		 5dzkc-6fflA:
undetectable
5dzkq-6fflA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_T_BEZT801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 6ffl MALTOSE/MALTODEXTRIN
TRANSPORT PERMEASE
HOMOLOGUE
(Bdellovibrio
bacteriovorus) 		4 / 5 SER A 331
ALA A 332
HIS A 115
LEU A 310
 None
 1.31A 5dzkf-6fflA:
undetectable
5dzkt-6fflA:
undetectable		 5dzkf-6fflA:
undetectable
5dzkt-6fflA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_T_BEZT801_1
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 6ffl MALTOSE/MALTODEXTRIN
TRANSPORT PERMEASE
HOMOLOGUE
(Bdellovibrio
bacteriovorus) 		4 / 8 SER A 331
ALA A 332
HIS A 115
LEU A 310
 None
 1.12A 5dzkF-6fflA:
undetectable
5dzkT-6fflA:
undetectable		 5dzkF-6fflA:
undetectable
5dzkT-6fflA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_U_BEZU801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 6ffl MALTOSE/MALTODEXTRIN
TRANSPORT PERMEASE
HOMOLOGUE
(Bdellovibrio
bacteriovorus) 		4 / 6 SER A 331
ALA A 332
HIS A 115
LEU A 310
 None
 1.19A 5dzkg-6fflA:
undetectable
5dzku-6fflA:
undetectable		 5dzkg-6fflA:
undetectable
5dzku-6fflA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L8D_B_ACTB601_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 6ffl MALTOSE/MALTODEXTRIN
TRANSPORT PERMEASE
HOMOLOGUE
(Bdellovibrio
bacteriovorus) 		3 / 3 THR A  42
PRO A  65
ASP A  67
 GLC  A 409 (-4.2A)
GLC  A 407 (-4.0A)
GLC  A 407 (-2.9A)
 0.88A 5l8dB-6fflA:
undetectable		 5l8dB-6fflA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MWU_B_ACTB601_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 6ffl MALTOSE/MALTODEXTRIN
TRANSPORT PERMEASE
HOMOLOGUE
(Bdellovibrio
bacteriovorus) 		3 / 3 THR A  42
PRO A  65
ASP A  67
 GLC  A 409 (-4.2A)
GLC  A 407 (-4.0A)
GLC  A 407 (-2.9A)
 0.88A 5mwuB-6fflA:
undetectable		 5mwuB-6fflA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WK9_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 6ffl MALTOSE/MALTODEXTRIN
TRANSPORT PERMEASE
HOMOLOGUE
(Bdellovibrio
bacteriovorus) 		4 / 7 PHE A  90
TYR A  89
THR A 295
LEU A 291
 None
 1.01A 5wk9A-6fflA:
undetectable		 5wk9A-6fflA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_A_ZOLA401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 6ffl MALTOSE/MALTODEXTRIN
TRANSPORT PERMEASE
HOMOLOGUE
(Bdellovibrio
bacteriovorus) 		4 / 7 ASP A 240
ARG A  16
GLN A 243
LYS A 224
 None
SO4  A 406 (-2.8A)
None
None
 1.42A 6g31A-6fflA:
undetectable		 6g31A-6fflA:
16.28