SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6fg7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_A_CELA602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 6fg7 INACTIVE LRR
RECEPTOR-LIKE
SERINE/THREONINE-PRO
TEIN KINASE BIR2
(Arabidopsis
thaliana) 		5 / 12 LEU A 109
ALA A 102
GLY A  39
SER A  43
LEU A  44
 None
 0.97A 5jw1A-6fg7A:
undetectable		 5jw1A-6fg7A:
9.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UAN_B_REAB503_1
(RETINOIC ACID
RECEPTOR BETA)		 6fg7 INACTIVE LRR
RECEPTOR-LIKE
SERINE/THREONINE-PRO
TEIN KINASE BIR2
(Arabidopsis
thaliana) 		5 / 12 LEU A 147
ILE A 143
ILE A 167
PHE A 180
VAL A 153
 None
 1.25A 5uanB-6fg7A:
undetectable		 5uanB-6fg7A:
11.54