SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6fg8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7W_A_MTXA301_1
(PTERIDINE REDUCTASE)		 6fg8 SOMATIC
EMBRYOGENESIS
RECEPTOR KINASE 1
(Arabidopsis
thaliana) 		5 / 12 ASP A 123
LEU A 148
TYR A 125
LEU A 143
LEU A 167
 None
 1.43A 1e7wA-6fg8A:
undetectable		 1e7wA-6fg8A:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EIZ_A_SAMA301_0
(FTSJ)		 6fg8 PROBABLE INACTIVE
RECEPTOR KINASE
AT1G27190
(Arabidopsis
thaliana) 		5 / 12 GLY B 134
GLY B 135
LEU B 103
LEU B 108
LEU B 120
 None
 0.98A 1eizA-6fg8B:
undetectable		 1eizA-6fg8B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H9Z_A_RWFA3001_1
(SERUM ALBUMIN)		 6fg8 PROBABLE INACTIVE
RECEPTOR KINASE
AT1G27190
(Arabidopsis
thaliana) 		5 / 11 ALA B  85
LEU B 108
LEU B  38
LEU B  34
SER B  91
 None
 1.16A 1h9zA-6fg8B:
undetectable		 1h9zA-6fg8B:
9.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_B_THAB2_1
(LIVER
CARBOXYLESTERASE I)		 6fg8 SOMATIC
EMBRYOGENESIS
RECEPTOR KINASE 1
(Arabidopsis
thaliana) 		5 / 11 LEU A 137
VAL A  74
LEU A 119
LEU A  95
LEU A 148
 None
 1.34A 1mx1B-6fg8A:
undetectable		 1mx1B-6fg8A:
11.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_L_TFPL202_1
(PROTEIN S100-A4)		 6fg8 SOMATIC
EMBRYOGENESIS
RECEPTOR KINASE 1
(Arabidopsis
thaliana) 		5 / 12 LEU A 148
ASP A 171
LEU A 137
ILE A 133
PHE A 187
 None
 1.18A 3ko0K-6fg8A:
undetectable
3ko0L-6fg8A:
undetectable
3ko0M-6fg8A:
undetectable
3ko0N-6fg8A:
undetectable		 3ko0K-6fg8A:
18.00
3ko0L-6fg8A:
18.00
3ko0M-6fg8A:
18.00
3ko0N-6fg8A:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		 6fg8 SOMATIC
EMBRYOGENESIS
RECEPTOR KINASE 1
(Arabidopsis
thaliana) 		4 / 6 THR A 162
ASN A 163
GLY A 138
ILE A 133
 NAG  A 308 (-3.8A)
NAG  A 310 ( 1.8A)
None
None
 1.00A 3w9tF-6fg8A:
undetectable		 3w9tF-6fg8A:
10.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KT0_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 6fg8 PROBABLE INACTIVE
RECEPTOR KINASE
AT1G27190
(Arabidopsis
thaliana) 		5 / 11 GLY B 193
ALA B 177
LEU B 176
ILE B  88
LEU B  92
 None
 1.03A 4kt0A-6fg8B:
undetectable
4kt0J-6fg8B:
undetectable		 4kt0A-6fg8B:
7.32
4kt0J-6fg8B:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KT0_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 6fg8 PROBABLE INACTIVE
RECEPTOR KINASE
AT1G27190
(Arabidopsis
thaliana) 		5 / 11 GLY B 194
ALA B 177
LEU B 176
ILE B  88
LEU B  92
 None
 1.00A 4kt0A-6fg8B:
undetectable
4kt0J-6fg8B:
undetectable		 4kt0A-6fg8B:
7.32
4kt0J-6fg8B:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WCX_C_SAMC503_0
(BIOTIN AND THIAMIN
SYNTHESIS ASSOCIATED)		 6fg8 SOMATIC
EMBRYOGENESIS
RECEPTOR KINASE 1
(Arabidopsis
thaliana) 		5 / 12 TYR A 101
GLY A  77
LEU A 119
LEU A 143
ARG A 144
 None
 1.12A 4wcxC-6fg8A:
undetectable		 4wcxC-6fg8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YIA_B_IMNB401_1
(THYROXINE-BINDING
GLOBULIN)		 6fg8 PROBABLE INACTIVE
RECEPTOR KINASE
AT1G27190
(Arabidopsis
thaliana) 		5 / 10 SER B 100
LEU B  34
SER B  76
LEU B  77
LEU B  84
 None
 1.16A 4yiaA-6fg8B:
undetectable		 4yiaA-6fg8B:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_F_4LEF401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 6fg8 SOMATIC
EMBRYOGENESIS
RECEPTOR KINASE 1
(Arabidopsis
thaliana) 		4 / 8 LEU A  89
THR A  39
LEU A  40
LEU A  36
 None
 0.69A 4z90F-6fg8A:
undetectable
4z90G-6fg8A:
undetectable
4z90H-6fg8A:
undetectable
4z90I-6fg8A:
undetectable
4z90J-6fg8A:
undetectable		 4z90F-6fg8A:
10.87
4z90G-6fg8A:
10.87
4z90H-6fg8A:
10.87
4z90I-6fg8A:
10.87
4z90J-6fg8A:
10.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EB3_A_UEGA202_1
(YFIR)		 6fg8 PROBABLE INACTIVE
RECEPTOR KINASE
AT1G27190
(Arabidopsis
thaliana) 		4 / 4 LEU B 120
ILE B 116
PRO B  89
LEU B 103
 None
 1.25A 5eb3A-6fg8B:
undetectable		 5eb3A-6fg8B:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_A_SAMA301_0
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 6fg8 PROBABLE INACTIVE
RECEPTOR KINASE
AT1G27190
(Arabidopsis
thaliana) 		5 / 12 LEU B 152
SER B 175
LEU B 133
GLY B 105
SER B 104
 None
 1.33A 5jglA-6fg8B:
undetectable		 5jglA-6fg8B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MWY_A_YNUA1101_0
(MINERALOCORTICOID
RECEPTOR)		 6fg8 PROBABLE INACTIVE
RECEPTOR KINASE
AT1G27190
(Arabidopsis
thaliana) 		5 / 12 LEU B 165
LEU B 150
SER B 129
LEU B 128
LEU B 157
 None
 1.11A 5mwyA-6fg8B:
undetectable		 5mwyA-6fg8B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TOA_A_ESTA601_1
(ESTROGEN RECEPTOR
BETA)		 6fg8 PROBABLE INACTIVE
RECEPTOR KINASE
AT1G27190
(Arabidopsis
thaliana) 		5 / 12 LEU B  34
LEU B  31
LEU B  98
ILE B  88
LEU B 120
 None
 1.03A 5toaA-6fg8B:
undetectable		 5toaA-6fg8B:
14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZJI_A_PQNA844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 6fg8 PROBABLE INACTIVE
RECEPTOR KINASE
AT1G27190
SOMATIC
EMBRYOGENESIS
RECEPTOR KINASE 1
(Arabidopsis
thaliana) 		5 / 10 PHE A 195
SER A 173
ARG A 147
ILE B  75
LEU A 170
 None
 1.32A 5zjiA-6fg8A:
undetectable
5zjiJ-6fg8A:
undetectable		 5zjiA-6fg8A:
15.85
5zjiJ-6fg8A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G9B_A_IXXA609_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN
ENVELOPE
GLYCOPROTEIN)		 6fg8 SOMATIC
EMBRYOGENESIS
RECEPTOR KINASE 1
(Arabidopsis
thaliana) 		5 / 7 LEU A  85
VAL A  74
LEU A  98
LEU A 116
LEU A  33
 None
 1.08A 6g9bA-6fg8A:
undetectable
6g9bB-6fg8A:
undetectable		 6g9bA-6fg8A:
24.14
6g9bB-6fg8A:
14.77