SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6fg9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9H_A_RAPA108_1
(FKBP12.6)		 6fg9 -
(-) 		5 / 12 GLU A 862
VAL A 864
PHE A 866
VAL A 800
ILE A 787
 None
 1.17A 1c9hA-6fg9A:
undetectable		 1c9hA-6fg9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FXH_B_PACB1001_0
(PENICILLIN ACYLASE)		 6fg9 -
(-) 		5 / 7 MET A 528
PHE A 558
SER A 589
ALA A 574
ILE A 573
 None
 1.36A 1fxhA-6fg9A:
undetectable
1fxhB-6fg9A:
undetectable		 1fxhA-6fg9A:
undetectable
1fxhB-6fg9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I7Q_A_BEZA1501_0
(ANTHRANILATE
SYNTHASE)		 6fg9 -
(-) 		5 / 11 ILE A 527
GLY A 529
THR A 519
LEU A 480
GLY A 531
 None
 1.15A 1i7qA-6fg9A:
undetectable		 1i7qA-6fg9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KF6_N_ACTN803_0
(FUMARATE REDUCTASE
FLAVOPROTEIN
FUMARATE REDUCTASE
IRON-SULFUR PROTEIN)		 6fg9 -
(-) 		4 / 6 TRP A 657
GLY A 551
ASP A 549
TYR A 471
 None
 1.16A 1kf6M-6fg9A:
undetectable
1kf6N-6fg9A:
undetectable		 1kf6M-6fg9A:
undetectable
1kf6N-6fg9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NW5_A_SAMA401_1
(MODIFICATION
METHYLASE RSRI)		 6fg9 -
(-) 		3 / 3 ASP A 658
HIS A 552
ASP A 661
 None
 0.80A 1nw5A-6fg9A:
undetectable		 1nw5A-6fg9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PBC_A_BHAA396_0
(P-HYDROXYBENZOATE
HYDROXYLASE)		 6fg9 -
(-) 		5 / 10 GLY A 450
VAL A 448
TRP A 657
LEU A 659
TYR A 675
 None
 1.29A 1pbcA-6fg9A:
undetectable		 1pbcA-6fg9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VPT_A_SAMA400_0
(VP39)		 6fg9 -
(-) 		5 / 12 LEU A1020
ILE A 884
GLY A 885
VAL A 955
ALA A 931
 None
 0.89A 1vptA-6fg9A:
undetectable		 1vptA-6fg9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_F_BEZF5023_0
(CES1 PROTEIN)		 6fg9 -
(-) 		4 / 6 LEU A 163
GLY A 238
SER A 234
LEU A 194
 None
 0.98A 1yajF-6fg9A:
undetectable		 1yajF-6fg9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXM_A_IMNA2002_1
(SERUM ALBUMIN)		 6fg9 -
(-) 		5 / 11 LEU A 662
ILE A 469
LEU A 456
PHE A 455
GLY A 453
 None
 1.19A 2bxmA-6fg9A:
undetectable		 2bxmA-6fg9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIA_B_CL9B401_2
(DEOXYCYTIDINE KINASE)		 6fg9 -
(-) 		4 / 4 ARG A 506
ASP A 444
LEU A 414
ARG A 449
 None
 1.12A 2ziaB-6fg9A:
undetectable		 2ziaB-6fg9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6R_B_CRNB603_1
(CREATINE KINASE
B-TYPE)		 6fg9 -
(-) 		4 / 6 THR A 290
VAL A 289
GLU A 251
SER A 270
 None
 1.12A 3b6rB-6fg9A:
undetectable		 3b6rB-6fg9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RV5_C_DXCC92_0
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 6fg9 -
(-) 		4 / 4 VAL A 572
PHE A 588
PHE A 601
VAL A 624
 None
 1.22A 3rv5C-6fg9A:
undetectable
3rv5D-6fg9A:
undetectable		 3rv5C-6fg9A:
undetectable
3rv5D-6fg9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JTP_A_ASCA802_0
(RRNA N-GLYCOSIDASE)		 6fg9 -
(-) 		4 / 5 ILE A 445
ASN A 413
TYR A 412
ILE A 443
 None
 1.07A 4jtpA-6fg9A:
undetectable		 4jtpA-6fg9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCE_A_RITA602_2
(CYTOCHROME P450 3A4)		 6fg9 -
(-) 		4 / 6 ARG A 183
PHE A 207
PHE A 232
THR A 201
 None
 1.02A 5vceA-6fg9A:
undetectable		 5vceA-6fg9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CB4_A_BEZA501_0
(CANAVALIN)		 6fg9 -
(-) 		4 / 8 LEU A1017
VAL A1062
LEU A1045
ILE A1050
 None
 0.87A 6cb4A-6fg9A:
undetectable		 6cb4A-6fg9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F32_B_ACTB602_0
(AMINE OXIDASE LKCE)		 6fg9 -
(-) 		4 / 6 TYR A 273
VAL A 246
VAL A 250
THR A 267
 None
 1.38A 6f32B-6fg9A:
undetectable		 6f32B-6fg9A:
undetectable