SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6fgk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LOQ_A_ACTA277_0
(UNIVERSAL STRESS
PROTEIN)		 6fgk GTP
PYROPHOSPHOKINASE
YWAC
(Bacillus
subtilis) 		3 / 3 ASP A 163
SER A 167
ARG A  58
 None
 1.02A 3loqA-6fgkA:
undetectable		 3loqA-6fgkA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VRJ_A_1KXA301_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN
10-MER PEPTIDE)		 6fgk GTP
PYROPHOSPHOKINASE
YWAC
(Bacillus
subtilis) 		5 / 12 TYR A  43
ILE A  39
VAL A 107
ILE A 157
ILE A  52
 None
 1.25A 3vrjA-6fgkA:
undetectable
3vrjC-6fgkA:
undetectable		 3vrjA-6fgkA:
13.57
3vrjC-6fgkA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F3T_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 6fgk GTP
PYROPHOSPHOKINASE
YWAC
(Bacillus
subtilis) 		4 / 6 LEU A 134
TYR A 122
LYS A 120
GLU A 154
 None
 0.83A 4f3tA-6fgkA:
undetectable		 4f3tA-6fgkA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4F_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 6fgk GTP
PYROPHOSPHOKINASE
YWAC
(Bacillus
subtilis) 		4 / 7 LEU A 134
TYR A 122
LYS A 120
GLU A 154
 None
 0.78A 4z4fA-6fgkA:
undetectable		 4z4fA-6fgkA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4G_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 6fgk GTP
PYROPHOSPHOKINASE
YWAC
(Bacillus
subtilis) 		4 / 6 LEU A 134
TYR A 122
LYS A 120
GLU A 154
 None
 0.83A 4z4gA-6fgkA:
undetectable		 4z4gA-6fgkA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T7B_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 6fgk GTP
PYROPHOSPHOKINASE
YWAC
(Bacillus
subtilis) 		4 / 7 LEU A 134
TYR A 122
LYS A 120
GLU A 154
 None
 0.77A 5t7bA-6fgkA:
undetectable		 5t7bA-6fgkA:
undetectable