SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6fhf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_D_DVAD8_0
(GRAMICIDIN A)		 6fhf -
(-) 		3 / 3 VAL A  98
VAL A 160
TRP A 174
 None
 0.88A 1av2C-6fhfA:
undetectable
1av2D-6fhfA:
undetectable		 1av2C-6fhfA:
undetectable
1av2D-6fhfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P93_D_DEXD4999_1
(GLUCOCORTICOID
RECEPTOR)		 6fhf -
(-) 		5 / 12 ARG A 191
PHE A 187
THR A 207
ILE A 216
PHE A 256
 None
 1.39A 1p93D-6fhfA:
undetectable		 1p93D-6fhfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q97_B_ADNB486_1
(SR PROTEIN KINASE)		 6fhf -
(-) 		4 / 4 VAL A  98
ALA A 186
LEU A 223
PHE A 187
 None
 1.15A 1q97B-6fhfA:
undetectable		 1q97B-6fhfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_D_DVAD8_0
(GRAMICIDIN D)		 6fhf -
(-) 		3 / 3 VAL A  98
VAL A 160
TRP A 174
 None
 0.91A 1w5uC-6fhfA:
undetectable
1w5uD-6fhfA:
undetectable		 1w5uC-6fhfA:
undetectable
1w5uD-6fhfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HKK_A_ALEA300_1
(CARBONIC ANHYDRASE 2)		 6fhf -
(-) 		4 / 6 ASN A 158
HIS A  95
ILE A 216
THR A 266
 None
 1.17A 2hkkA-6fhfA:
undetectable		 2hkkA-6fhfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_A_DVAA8_0
(GRAMICIDIN D)		 6fhf -
(-) 		3 / 3 VAL A 160
TRP A 174
VAL A  98
 None
 0.88A 2izqA-6fhfA:
undetectable
2izqB-6fhfA:
undetectable		 2izqA-6fhfA:
undetectable
2izqB-6fhfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_F_BEZF1222_0
(PEROXIREDOXIN 6.)		 6fhf -
(-) 		4 / 7 PRO A 211
PRO A 163
VAL A 161
GLU A 214
 None
 1.05A 2v41E-6fhfA:
undetectable
2v41F-6fhfA:
undetectable		 2v41E-6fhfA:
undetectable
2v41F-6fhfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_B_DVAB8_0
(GRAMICIDIN D)		 6fhf -
(-) 		3 / 3 VAL A  98
VAL A 160
TRP A 174
 None
 0.80A 3l8lA-6fhfA:
undetectable
3l8lB-6fhfA:
undetectable		 3l8lA-6fhfA:
undetectable
3l8lB-6fhfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNC_A_SALA1338_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 6fhf -
(-) 		5 / 9 LEU A  20
PHE A  52
THR A 317
VAL A 316
LEU A 268
 None
 1.46A 3uncA-6fhfA:
undetectable		 3uncA-6fhfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNC_B_SALB1338_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 6fhf -
(-) 		5 / 9 LEU A  20
PHE A  52
THR A 317
VAL A 316
LEU A 268
 None
 1.46A 3uncB-6fhfA:
undetectable		 3uncB-6fhfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7A_B_RGZB601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 6fhf -
(-) 		5 / 12 LEU A 302
LEU A 305
LEU A 309
ILE A 265
ILE A 249
 None
 1.14A 4a7aB-6fhfA:
undetectable		 4a7aB-6fhfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_A_SAMA601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 6fhf -
(-) 		4 / 5 ASN A 336
ALA A 280
GLY A 340
ASP A 342
 None
 0.94A 4n48A-6fhfA:
undetectable		 4n48A-6fhfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RZV_A_032A801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 6fhf -
(-) 		4 / 5 ILE A 321
VAL A  34
PHE A  94
HIS A  51
 None
 1.16A 4rzvA-6fhfA:
undetectable		 4rzvA-6fhfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JMN_A_FUAA1101_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 6fhf -
(-) 		4 / 5 ILE A 361
ILE A  12
HIS A  11
VAL A 353
 None
 1.01A 5jmnA-6fhfA:
undetectable		 5jmnA-6fhfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MWY_A_YNUA1101_1
(MINERALOCORTICOID
RECEPTOR)		 6fhf -
(-) 		4 / 6 ARG A 191
PHE A 187
THR A 207
PHE A 256
 None
 1.45A 5mwyA-6fhfA:
undetectable		 5mwyA-6fhfA:
undetectable