SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6fhm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZI9_A_CL9A401_2
(DEOXYCYTIDINE KINASE)		 6fhm -
(-) 		3 / 3 ASP A 112
PHE A 113
LEU A 115
 None
 0.62A 2zi9A-6fhmA:
undetectable		 2zi9A-6fhmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6fhm -
(-) 		4 / 6 GLN A 139
PHE A 140
PHE A 127
LEU A 115
 None
 1.02A 3ablP-6fhmA:
undetectable
3ablW-6fhmA:
undetectable		 3ablP-6fhmA:
undetectable
3ablW-6fhmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 6fhm -
(-) 		4 / 7 GLN A 139
PHE A 140
PHE A 127
LEU A 115
 None
 1.03A 3ag2C-6fhmA:
undetectable		 3ag2C-6fhmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 6fhm -
(-) 		4 / 6 GLN A 139
PHE A 140
PHE A 127
LEU A 115
 None
 1.11A 5b1bC-6fhmA:
undetectable
5b1bJ-6fhmA:
undetectable		 5b1bC-6fhmA:
undetectable
5b1bJ-6fhmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTD_E_GFNE101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 6fhm -
(-) 		4 / 7 ALA A 142
ASP A 100
ARG A  95
GLU A  47
 None
 0.86A 5btdA-6fhmA:
undetectable
5btdB-6fhmA:
undetectable
5btdC-6fhmA:
undetectable		 5btdA-6fhmA:
undetectable
5btdB-6fhmA:
undetectable
5btdC-6fhmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTD_G_GFNG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 6fhm -
(-) 		4 / 7 ALA A 142
ASP A 100
ARG A  95
GLU A  47
 None
 0.85A 5btdA-6fhmA:
undetectable
5btdC-6fhmA:
undetectable
5btdD-6fhmA:
undetectable		 5btdA-6fhmA:
undetectable
5btdC-6fhmA:
undetectable
5btdD-6fhmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 6fhm -
(-) 		4 / 6 GLN A 139
PHE A 140
PHE A 127
LEU A 115
 None
 1.01A 5z84P-6fhmA:
undetectable
5z84W-6fhmA:
undetectable		 5z84P-6fhmA:
undetectable
5z84W-6fhmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 6fhm -
(-) 		4 / 6 GLN A 139
PHE A 140
PHE A 127
LEU A 115
 None
 1.02A 5z85P-6fhmA:
undetectable
5z85W-6fhmA:
undetectable		 5z85P-6fhmA:
undetectable
5z85W-6fhmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 6fhm -
(-) 		4 / 6 GLN A 139
PHE A 140
PHE A 127
LEU A 115
 None
 0.98A 5z86C-6fhmA:
undetectable
5z86J-6fhmA:
undetectable		 5z86C-6fhmA:
undetectable
5z86J-6fhmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 6fhm -
(-) 		4 / 6 GLN A 139
PHE A 140
PHE A 127
LEU A 115
 None
 1.03A 5z86P-6fhmA:
undetectable
5z86W-6fhmA:
undetectable		 5z86P-6fhmA:
undetectable
5z86W-6fhmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 6fhm -
(-) 		4 / 6 GLN A 139
PHE A 140
PHE A 127
LEU A 115
 None
 1.03A 5zcoP-6fhmA:
undetectable
5zcoW-6fhmA:
undetectable		 5zcoP-6fhmA:
undetectable
5zcoW-6fhmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 6fhm -
(-) 		4 / 6 GLN A 139
PHE A 140
PHE A 127
LEU A 115
 None
 0.98A 5zcpC-6fhmA:
undetectable
5zcpJ-6fhmA:
undetectable		 5zcpC-6fhmA:
undetectable
5zcpJ-6fhmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 6fhm -
(-) 		4 / 6 GLN A 139
PHE A 140
PHE A 127
LEU A 115
 None
 1.00A 5zcpP-6fhmA:
undetectable
5zcpW-6fhmA:
undetectable		 5zcpP-6fhmA:
undetectable
5zcpW-6fhmA:
undetectable