SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6fhv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AGM_A_ACRA495_1
(GLUCOAMYLASE-471)		 6fhv GLUCOAMYLASE
(Penicillium
oxalicum) 		12 / 12 ALA A  66
TYR A  75
TRP A  79
ARG A  81
ASP A  82
TRP A 154
GLY A 155
GLU A 214
ARG A 341
TYR A 347
TRP A 353
GLU A 436
 B3P  A 652 ( 3.9A)
B3P  A 652 (-4.1A)
B3P  A 652 ( 4.1A)
B3P  A 652 (-4.0A)
B3P  A 652 (-2.8A)
B3P  A 652 (-4.3A)
None
B3P  A 652 (-3.4A)
B3P  A 652 (-2.8A)
B3P  A 652 ( 3.8A)
None
B3P  A 652 ( 4.6A)
 0.36A 1agmA-6fhvA:
62.7		 1agmA-6fhvA:
8.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AGM_A_ACRA495_2
(GLUCOAMYLASE-471)		 6fhv GLUCOAMYLASE
(Penicillium
oxalicum) 		4 / 4 TRP A 212
GLU A 213
LEU A 451
TRP A 453
 None
B3P  A 652 (-3.7A)
None
None
 0.25A 1agmA-6fhvA:
62.7		 1agmA-6fhvA:
8.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AGM_A_ACRA496_1
(GLUCOAMYLASE-471)		 6fhv GLUCOAMYLASE
(Penicillium
oxalicum) 		12 / 12 ALA A  66
TYR A  75
TRP A  79
ARG A  81
ASP A  82
TRP A 154
GLY A 155
GLU A 214
ARG A 341
TYR A 347
TRP A 353
GLU A 436
 B3P  A 652 ( 3.9A)
B3P  A 652 (-4.1A)
B3P  A 652 ( 4.1A)
B3P  A 652 (-4.0A)
B3P  A 652 (-2.8A)
B3P  A 652 (-4.3A)
None
B3P  A 652 (-3.4A)
B3P  A 652 (-2.8A)
B3P  A 652 ( 3.8A)
None
B3P  A 652 ( 4.6A)
 0.36A 1agmA-6fhvA:
62.7		 1agmA-6fhvA:
8.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AGM_A_ACRA496_2
(GLUCOAMYLASE-471)		 6fhv GLUCOAMYLASE
(Penicillium
oxalicum) 		4 / 5 TRP A 212
GLU A 213
LEU A 451
TRP A 453
 None
B3P  A 652 (-3.7A)
None
None
 0.25A 1agmA-6fhvA:
62.7		 1agmA-6fhvA:
8.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4S_A_TPVA201_1
(PROTEIN (HIV-1
PROTEASE))		 6fhv GLUCOAMYLASE
(Penicillium
oxalicum) 		5 / 10 LEU A 197
ALA A 163
ASP A 160
ILE A 223
PRO A 251
 None
 1.20A 1d4sA-6fhvA:
undetectable		 1d4sA-6fhvA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DED_A_QPSA2001_1
(CYCLODEXTRIN
GLUCANOTRANSFERASE)		 6fhv GLUCOAMYLASE
(Penicillium
oxalicum) 		4 / 6 TRP A 542
LYS A 578
GLY A 593
ASN A 595
 PEG  A 654 (-3.6A)
None
None
PEG  A 654 ( 4.4A)
 1.04A 1dedA-6fhvA:
10.8		 1dedA-6fhvA:
7.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DED_A_QPSA2001_1
(CYCLODEXTRIN
GLUCANOTRANSFERASE)		 6fhv GLUCOAMYLASE
(Penicillium
oxalicum) 		4 / 6 TRP A 542
LYS A 578
TRP A 590
ASN A 595
 PEG  A 654 (-3.6A)
None
PEG  A 654 ( 4.2A)
PEG  A 654 ( 4.4A)
 0.44A 1dedA-6fhvA:
10.8		 1dedA-6fhvA:
7.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EE2_A_CHDA1150_0
(ALCOHOL
DEHYDROGENASE)		 6fhv GLUCOAMYLASE
(Penicillium
oxalicum) 		5 / 11 SER A  41
LEU A 434
LEU A  30
LEU A 358
ILE A  34
 None
 1.38A 1ee2A-6fhvA:
undetectable		 1ee2A-6fhvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EE2_B_CHDB1250_1
(ALCOHOL
DEHYDROGENASE)		 6fhv GLUCOAMYLASE
(Penicillium
oxalicum) 		5 / 11 SER A  41
LEU A 434
LEU A  30
LEU A 358
ILE A  34
 None
 1.38A 1ee2B-6fhvA:
undetectable		 1ee2B-6fhvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GAH_A_ACRA497_1
(GLUCOAMYLASE-471)		 6fhv GLUCOAMYLASE
(Penicillium
oxalicum) 		11 / 12 TYR A  75
TRP A  79
ARG A  81
ASP A  82
TRP A 154
GLY A 155
GLU A 213
GLU A 214
TYR A 347
TRP A 353
GLU A 436
 B3P  A 652 (-4.1A)
B3P  A 652 ( 4.1A)
B3P  A 652 (-4.0A)
B3P  A 652 (-2.8A)
B3P  A 652 (-4.3A)
None
B3P  A 652 (-3.7A)
B3P  A 652 (-3.4A)
B3P  A 652 ( 3.8A)
None
B3P  A 652 ( 4.6A)
 0.31A 1gahA-6fhvA:
62.7		 1gahA-6fhvA:
8.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GAH_A_ACRA497_2
(GLUCOAMYLASE-471)		 6fhv GLUCOAMYLASE
(Penicillium
oxalicum) 		5 / 6 ALA A  66
TRP A 212
ARG A 341
LEU A 451
TRP A 453
 B3P  A 652 ( 3.9A)
None
B3P  A 652 (-2.8A)
None
None
 0.44A 1gahA-6fhvA:
62.7		 1gahA-6fhvA:
8.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_C_BEZC1162_0
(PEROXIREDOXIN 5)		 6fhv GLUCOAMYLASE
(Penicillium
oxalicum) 		5 / 9 PRO A 141
THR A  80
GLY A 161
PHE A 143
GLY A 137
 None
 1.30A 1h4oC-6fhvA:
undetectable
1h4oD-6fhvA:
undetectable		 1h4oC-6fhvA:
undetectable
1h4oD-6fhvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LF9_A_ACRA700_1
(GLUCOAMYLASE)		 6fhv GLUCOAMYLASE
(Penicillium
oxalicum) 		9 / 12 ALA A  66
TYR A  75
TRP A  79
ARG A  81
ASP A  82
GLU A 214
ARG A 341
TYR A 347
TRP A 453
 B3P  A 652 ( 3.9A)
B3P  A 652 (-4.1A)
B3P  A 652 ( 4.1A)
B3P  A 652 (-4.0A)
B3P  A 652 (-2.8A)
B3P  A 652 (-3.4A)
B3P  A 652 (-2.8A)
B3P  A 652 ( 3.8A)
None
 0.46A 1lf9A-6fhvA:
10.4		 1lf9A-6fhvA:
8.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LF9_A_ACRA700_1
(GLUCOAMYLASE)		 6fhv GLUCOAMYLASE
(Penicillium
oxalicum) 		5 / 12 ALA A  66
TYR A  75
TRP A 154
GLU A 214
TYR A 347
 B3P  A 652 ( 3.9A)
B3P  A 652 (-4.1A)
B3P  A 652 (-4.3A)
B3P  A 652 (-3.4A)
B3P  A 652 ( 3.8A)
 1.01A 1lf9A-6fhvA:
10.4		 1lf9A-6fhvA:
8.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LF9_A_ACRA700_2
(GLUCOAMYLASE)		 6fhv GLUCOAMYLASE
(Penicillium
oxalicum) 		4 / 4 TRP A 212
GLU A 213
TRP A 353
LEU A 451
 None
B3P  A 652 (-3.7A)
None
None
 0.30A 1lf9A-6fhvA:
10.4		 1lf9A-6fhvA:
8.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LF9_B_ACRB701_1
(GLUCOAMYLASE)		 6fhv GLUCOAMYLASE
(Penicillium
oxalicum) 		9 / 12 ALA A  66
TYR A  75
TRP A  79
ARG A  81
ASP A  82
GLU A 214
ARG A 341
TYR A 347
TRP A 353
 B3P  A 652 ( 3.9A)
B3P  A 652 (-4.1A)
B3P  A 652 ( 4.1A)
B3P  A 652 (-4.0A)
B3P  A 652 (-2.8A)
B3P  A 652 (-3.4A)
B3P  A 652 (-2.8A)
B3P  A 652 ( 3.8A)
None
 0.36A 1lf9B-6fhvA:
10.4		 1lf9B-6fhvA:
8.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LF9_B_ACRB701_1
(GLUCOAMYLASE)		 6fhv GLUCOAMYLASE
(Penicillium
oxalicum) 		5 / 12 ALA A  66
TYR A  75
TRP A 154
GLU A 214
TYR A 347
 B3P  A 652 ( 3.9A)
B3P  A 652 (-4.1A)
B3P  A 652 (-4.3A)
B3P  A 652 (-3.4A)
B3P  A 652 ( 3.8A)
 1.00A 1lf9B-6fhvA:
10.4		 1lf9B-6fhvA:
8.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LF9_B_ACRB701_1
(GLUCOAMYLASE)		 6fhv GLUCOAMYLASE
(Penicillium
oxalicum) 		6 / 12 TRP A  79
GLN A 158
GLU A 214
ARG A 341
TYR A 347
TRP A 353
 B3P  A 652 ( 4.1A)
None
B3P  A 652 (-3.4A)
B3P  A 652 (-2.8A)
B3P  A 652 ( 3.8A)
None
 1.39A 1lf9B-6fhvA:
10.4		 1lf9B-6fhvA:
8.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LF9_B_ACRB701_2
(GLUCOAMYLASE)		 6fhv GLUCOAMYLASE
(Penicillium
oxalicum) 		4 / 4 TRP A 212
GLU A 213
LEU A 451
TRP A 453
 None
B3P  A 652 (-3.7A)
None
None
 0.45A 1lf9B-6fhvA:
10.4		 1lf9B-6fhvA:
8.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N2X_B_SAMB402_0
(S-ADENOSYL-METHYLTRA
NSFERASE MRAW)		 6fhv GLUCOAMYLASE
(Penicillium
oxalicum) 		5 / 12 GLY A 139
GLU A 140
GLY A 137
GLY A 130
GLY A 208
 None
 0.93A 1n2xB-6fhvA:
undetectable		 1n2xB-6fhvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC685_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 6fhv GLUCOAMYLASE
(Penicillium
oxalicum) 		4 / 8 PRO A 294
ASP A 293
LYS A 476
SER A 477
 None
 1.21A 1p7lC-6fhvA:
undetectable		 1p7lC-6fhvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC885_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 6fhv GLUCOAMYLASE
(Penicillium
oxalicum) 		4 / 8 PRO A 294
ASP A 293
LYS A 476
SER A 477
 None
 1.21A 1p7lD-6fhvA:
undetectable		 1p7lD-6fhvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ULV_A_ACRA3000_1
(GLUCODEXTRANASE)		 6fhv GLUCOAMYLASE
(Penicillium
oxalicum) 		9 / 12 ALA A  66
TYR A  75
TRP A  79
ARG A  81
ASP A  82
GLU A 214
ARG A 341
TYR A 347
TRP A 353
 B3P  A 652 ( 3.9A)
B3P  A 652 (-4.1A)
B3P  A 652 ( 4.1A)
B3P  A 652 (-4.0A)
B3P  A 652 (-2.8A)
B3P  A 652 (-3.4A)
B3P  A 652 (-2.8A)
B3P  A 652 ( 3.8A)
None
 0.45A 1ulvA-6fhvA:
30.6		 1ulvA-6fhvA:
6.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ULV_A_ACRA3000_2
(GLUCODEXTRANASE)		 6fhv GLUCOAMYLASE
(Penicillium
oxalicum) 		4 / 5 TRP A 212
GLU A 213
LEU A 451
TRP A 453
 None
B3P  A 652 (-3.7A)
None
None
 0.37A 1ulvA-6fhvA:
30.7		 1ulvA-6fhvA:
6.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y7I_A_SALA501_1
(SALICYLIC
ACID-BINDING PROTEIN
2)		 6fhv GLUCOAMYLASE
(Penicillium
oxalicum) 		5 / 9 GLY A  38
SER A  41
TYR A 354
PHE A  33
LEU A 358
 None
 1.27A 1y7iA-6fhvA:
undetectable		 1y7iA-6fhvA:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C6N_B_LPRB705_2
(ANGIOTENSIN-CONVERTI
NG ENZYME, SOMATIC
ISOFORM)		 6fhv GLUCOAMYLASE
(Penicillium
oxalicum) 		3 / 3 ALA A 224
THR A 291
PHE A 261
 None
 0.76A 2c6nB-6fhvA:
undetectable		 2c6nB-6fhvA:
10.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F6D_A_ACRA995_1
(GLUCOAMYLASE GLU1)		 6fhv GLUCOAMYLASE
(Penicillium
oxalicum) 		12 / 12 ALA A  66
TYR A  75
TRP A  79
ARG A  81
ASP A  82
TRP A 154
GLY A 155
GLU A 214
ARG A 341
TYR A 347
TRP A 353
GLU A 436
 B3P  A 652 ( 3.9A)
B3P  A 652 (-4.1A)
B3P  A 652 ( 4.1A)
B3P  A 652 (-4.0A)
B3P  A 652 (-2.8A)
B3P  A 652 (-4.3A)
None
B3P  A 652 (-3.4A)
B3P  A 652 (-2.8A)
B3P  A 652 ( 3.8A)
None
B3P  A 652 ( 4.6A)
 0.44A 2f6dA-6fhvA:
44.5		 2f6dA-6fhvA:
11.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F6D_A_ACRA995_2
(GLUCOAMYLASE GLU1)		 6fhv GLUCOAMYLASE
(Penicillium
oxalicum) 		4 / 4 TRP A 212
GLU A 213
LEU A 451
TRP A 453
 None
B3P  A 652 (-3.7A)
None
None
 0.20A 2f6dA-6fhvA:
44.5		 2f6dA-6fhvA:
11.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_C_SAMC1003_1
(SAM DEPENDENT
METHYLTRANSFERASE)		 6fhv GLUCOAMYLASE
(Penicillium
oxalicum) 		4 / 4 ASP A 210
ASP A 216
ASP A 160
GLY A 155
 None
 1.13A 2igtC-6fhvA:
undetectable		 2igtC-6fhvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J0D_A_ERYA1498_0
(CYTOCHROME P450 3A4)		 6fhv GLUCOAMYLASE
(Penicillium
oxalicum) 		5 / 12 ILE A  45
PHE A 455
ALA A 456
ALA A 461
ARG A 465
 None
 0.99A 2j0dA-6fhvA:
undetectable		 2j0dA-6fhvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NOA_B_3TCB302_1
(DEOXYCYTIDINE KINASE)		 6fhv GLUCOAMYLASE
(Penicillium
oxalicum) 		5 / 11 LEU A 374
GLN A 304
ALA A 296
ASP A 293
PHE A 292
 None
 1.48A 2noaB-6fhvA:
undetectable		 2noaB-6fhvA:
15.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XCT_X_CPFX1020_1
(DNA GYRASE SUBUNIT
B, DNA GYRASE
SUBUNIT A)		 6fhv GLUCOAMYLASE
(Penicillium
oxalicum) 		4 / 4 ARG A 156
GLY A 139
GLU A 140
SER A 219
 None
 1.31A 2xctS-6fhvA:
undetectable
2xctU-6fhvA:
undetectable		 2xctS-6fhvA:
8.50
2xctU-6fhvA:
8.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 6fhv GLUCOAMYLASE
(Penicillium
oxalicum) 		4 / 7 LEU A 211
GLN A 158
PHE A 221
LEU A 286
 None
 1.04A 3ag2C-6fhvA:
undetectable		 3ag2C-6fhvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKW_B_DR7B100_2
(PROTEASE)		 6fhv GLUCOAMYLASE
(Penicillium
oxalicum) 		5 / 12 GLY A 572
ALA A 600
VAL A 597
ALA A 538
ILE A 569
 None
 0.88A 3ekwB-6fhvA:
undetectable		 3ekwB-6fhvA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_A_CHDA153_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 6fhv GLUCOAMYLASE
(Penicillium
oxalicum) 		4 / 5 ILE A 513
THR A 573
PHE A 575
PHE A 518
 None
 1.29A 3em0A-6fhvA:
undetectable		 3em0A-6fhvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IB0_A_DIFA701_1
(LACTOTRANSFERRIN)		 6fhv GLUCOAMYLASE
(Penicillium
oxalicum) 		4 / 4 PRO A 343
TYR A 342
GLY A 279
THR A 268
 None
 1.37A 3ib0A-6fhvA:
undetectable		 3ib0A-6fhvA:
14.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_A_ACTA4_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 6fhv GLUCOAMYLASE
(Penicillium
oxalicum) 		4 / 4 LEU A  49
GLY A  53
GLY A  51
THR A  59
 None
 0.97A 3si7A-6fhvA:
undetectable		 3si7A-6fhvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_D_BEZD1_0
(HEME-BINDING PROTEIN
HUTZ)		 6fhv GLUCOAMYLASE
(Penicillium
oxalicum) 		4 / 6 ARG A  81
GLN A 158
PRO A 162
LEU A 164
 B3P  A 652 (-4.0A)
None
None
None
 1.35A 3tgvD-6fhvA:
undetectable		 3tgvD-6fhvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_D_ACTD502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 6fhv GLUCOAMYLASE
(Penicillium
oxalicum) 		3 / 3 GLY A 217
THR A 273
ASN A 270
 None
 0.61A 3v4tD-6fhvA:
undetectable		 3v4tD-6fhvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WXO_A_NIZA803_1
(CATALASE-PEROXIDASE)		 6fhv GLUCOAMYLASE
(Penicillium
oxalicum) 		4 / 4 ASP A 281
THR A 268
VAL A 215
SER A 278
 None
 1.07A 3wxoA-6fhvA:
undetectable		 3wxoA-6fhvA:
7.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEU_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 6fhv GLUCOAMYLASE
(Penicillium
oxalicum) 		4 / 7 ASP A 345
ASP A 210
GLU A 436
ASP A 281
 None
None
B3P  A 652 ( 4.6A)
None
 1.19A 4feuB-6fhvA:
undetectable		 4feuB-6fhvA:
12.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEU_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 6fhv GLUCOAMYLASE
(Penicillium
oxalicum) 		4 / 8 ASP A 345
ASP A 210
GLU A 436
ASP A 281
 None
None
B3P  A 652 ( 4.6A)
None
 0.91A 4feuD-6fhvA:
undetectable		 4feuD-6fhvA:
12.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 6fhv GLUCOAMYLASE
(Penicillium
oxalicum) 		4 / 7 ASP A 345
ASP A 210
GLU A 436
ASP A 281
 None
None
B3P  A 652 ( 4.6A)
None
 0.95A 4fevB-6fhvA:
undetectable		 4fevB-6fhvA:
12.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEW_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 6fhv GLUCOAMYLASE
(Penicillium
oxalicum) 		4 / 7 ASP A 345
ASP A 210
GLU A 436
ASP A 281
 None
None
B3P  A 652 ( 4.6A)
None
 0.97A 4fewB-6fhvA:
undetectable		 4fewB-6fhvA:
12.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FR8_A_TNGA601_1
(ALDEHYDE
DEHYDROGENASE,
MITOCHONDRIAL)		 6fhv GLUCOAMYLASE
(Penicillium
oxalicum) 		5 / 11 PHE A 261
LEU A 258
GLN A 226
SER A 219
ASP A 283
 None
 1.49A 4fr8A-6fhvA:
undetectable		 4fr8A-6fhvA:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 6fhv GLUCOAMYLASE
(Penicillium
oxalicum) 		4 / 8 ASP A 345
ASP A 210
GLU A 436
ASP A 281
 None
None
B3P  A 652 ( 4.6A)
None
 0.96A 4gkhD-6fhvA:
undetectable		 4gkhD-6fhvA:
12.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KF9_A_ACTA408_0
(GLUTATHIONE
S-TRANSFERASE
PROTEIN)		 6fhv GLUCOAMYLASE
(Penicillium
oxalicum) 		4 / 6 THR A 551
PRO A 549
PHE A 150
PHE A 548
 None
 1.25A 4kf9A-6fhvA:
undetectable		 4kf9A-6fhvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 6fhv GLUCOAMYLASE
(Penicillium
oxalicum) 		4 / 8 PRO A 294
ASP A 293
LYS A 476
SER A 477
 None
 1.13A 4kttA-6fhvA:
undetectable		 4kttA-6fhvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTP_A_SAMA301_0
(DNA ADENINE
METHYLASE)		 6fhv GLUCOAMYLASE
(Penicillium
oxalicum) 		5 / 12 GLY A 208
SER A 219
SER A 136
ASP A 160
PRO A 141
 None
 1.30A 4rtpA-6fhvA:
undetectable		 4rtpA-6fhvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UIN_H_QI9H1226_0
(FAB 314.3)		 6fhv GLUCOAMYLASE
(Penicillium
oxalicum) 		5 / 12 SER A 457
ARG A  40
PHE A  33
GLY A 432
LEU A 434
 None
 1.24A 4uinH-6fhvA:
2.1
4uinL-6fhvA:
2.8		 4uinH-6fhvA:
undetectable
4uinL-6fhvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4USW_A_ACTA1470_0
(ADENYLATE CYCLASE
TYPE 10)		 6fhv GLUCOAMYLASE
(Penicillium
oxalicum) 		4 / 6 LEU A 358
LEU A 423
VAL A 424
PHE A 420
 None
 1.02A 4uswA-6fhvA:
undetectable		 4uswA-6fhvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_A_MZMA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 6fhv GLUCOAMYLASE
(Penicillium
oxalicum) 		5 / 12 ASP A 319
HIS A 314
VAL A 318
VAL A 339
ALA A 417
 None
 0.99A 4yhaA-6fhvA:
undetectable		 4yhaA-6fhvA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_B_MZMB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 6fhv GLUCOAMYLASE
(Penicillium
oxalicum) 		5 / 10 ASP A 319
HIS A 314
VAL A 318
VAL A 339
ALA A 417
 None
 0.99A 4yhaB-6fhvA:
undetectable		 4yhaB-6fhvA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDQ_V_MFXV2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 6fhv GLUCOAMYLASE
(Penicillium
oxalicum) 		4 / 5 SER A 219
ARG A 156
GLY A 139
GLU A 140
 None
 1.08A 5cdqR-6fhvA:
undetectable
5cdqS-6fhvA:
undetectable
5cdqT-6fhvA:
undetectable		 5cdqR-6fhvA:
10.82
5cdqS-6fhvA:
18.13
5cdqT-6fhvA:
10.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0O_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 6fhv GLUCOAMYLASE
(Penicillium
oxalicum) 		5 / 12 ILE A  91
ALA A  87
PHE A  64
ALA A 168
VAL A 116
 None
 1.10A 5n0oB-6fhvA:
undetectable		 5n0oB-6fhvA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CI6_A_NBOA607_1
(SERUM ALBUMIN)		 6fhv GLUCOAMYLASE
(Penicillium
oxalicum) 		4 / 7 ASP A 299
ASN A 479
ALA A 475
GLU A 295
 None
 1.01A 6ci6A-6fhvA:
undetectable		 6ci6A-6fhvA:
19.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6FHW_A_ACRA801_1
(GLUCOAMYLASE P)		 6fhv GLUCOAMYLASE
(Penicillium
oxalicum) 		12 / 12 ALA A  66
TYR A  75
TRP A  79
ARG A  81
ASP A  82
TRP A 154
GLY A 155
GLU A 214
ARG A 341
TYR A 347
TRP A 353
TRP A 453
 B3P  A 652 ( 3.9A)
B3P  A 652 (-4.1A)
B3P  A 652 ( 4.1A)
B3P  A 652 (-4.0A)
B3P  A 652 (-2.8A)
B3P  A 652 (-4.3A)
None
B3P  A 652 (-3.4A)
B3P  A 652 (-2.8A)
B3P  A 652 ( 3.8A)
None
None
 0.44A 6fhwA-6fhvA:
59.3		 6fhwA-6fhvA:
35.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6FHW_A_ACRA801_2
(GLUCOAMYLASE P)		 6fhv GLUCOAMYLASE
(Penicillium
oxalicum) 		3 / 3 TRP A 212
GLU A 213
GLU A 436
 None
B3P  A 652 (-3.7A)
B3P  A 652 ( 4.6A)
 0.26A 6fhwA-6fhvA:
59.3		 6fhwA-6fhvA:
35.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6FHW_A_ACRA801_2
(GLUCOAMYLASE P)		 6fhv GLUCOAMYLASE
(Penicillium
oxalicum) 		3 / 3 TRP A 453
GLU A 436
GLU A 213
 None
B3P  A 652 ( 4.6A)
B3P  A 652 (-3.7A)
 0.87A 6fhwA-6fhvA:
59.3		 6fhwA-6fhvA:
35.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6FHW_B_ACRB801_1
(GLUCOAMYLASE P)		 6fhv GLUCOAMYLASE
(Penicillium
oxalicum) 		12 / 12 ALA A  66
TYR A  75
TRP A  79
ARG A  81
ASP A  82
TRP A 154
GLY A 155
GLU A 214
ARG A 341
TYR A 347
TRP A 353
TRP A 453
 B3P  A 652 ( 3.9A)
B3P  A 652 (-4.1A)
B3P  A 652 ( 4.1A)
B3P  A 652 (-4.0A)
B3P  A 652 (-2.8A)
B3P  A 652 (-4.3A)
None
B3P  A 652 (-3.4A)
B3P  A 652 (-2.8A)
B3P  A 652 ( 3.8A)
None
None
 0.44A 6fhwB-6fhvA:
59.7		 6fhwB-6fhvA:
35.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6FHW_B_ACRB801_2
(GLUCOAMYLASE P)		 6fhv GLUCOAMYLASE
(Penicillium
oxalicum) 		4 / 4 TRP A 212
GLU A 213
GLU A 436
LEU A 451
 None
B3P  A 652 (-3.7A)
B3P  A 652 ( 4.6A)
None
 0.34A 6fhwB-6fhvA:
59.7		 6fhwB-6fhvA:
35.53