SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6fhw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AGM_A_ACRA495_1
(GLUCOAMYLASE-471)		 6fhw GLUCOAMYLASE P
(Amorphotheca
resinae) 		12 / 12 ALA A  67
TYR A  76
TRP A  80
ARG A  82
ASP A  83
TRP A 149
GLY A 150
GLU A 209
ARG A 335
TYR A 341
TRP A 347
GLU A 432
 ACR  A 801 (-3.5A)
ACR  A 801 (-4.3A)
ACR  A 801 (-3.3A)
ACR  A 801 (-4.0A)
ACR  A 801 (-2.7A)
ACR  A 801 (-3.7A)
ACR  A 801 (-3.1A)
ACR  A 801 (-3.9A)
ACR  A 801 (-2.8A)
ACR  A 801 ( 3.9A)
None
ACR  A 801 (-4.4A)
 0.34A 1agmA-6fhwA:
60.6		 1agmA-6fhwA:
10.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AGM_A_ACRA495_2
(GLUCOAMYLASE-471)		 6fhw GLUCOAMYLASE P
(Amorphotheca
resinae) 		4 / 4 TRP A 207
GLU A 208
LEU A 447
TRP A 449
 None
ACR  A 801 (-3.9A)
None
None
 0.27A 1agmA-6fhwA:
60.6		 1agmA-6fhwA:
10.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AGM_A_ACRA496_1
(GLUCOAMYLASE-471)		 6fhw GLUCOAMYLASE P
(Amorphotheca
resinae) 		12 / 12 ALA A  67
TYR A  76
TRP A  80
ARG A  82
ASP A  83
TRP A 149
GLY A 150
GLU A 209
ARG A 335
TYR A 341
TRP A 347
GLU A 432
 ACR  A 801 (-3.5A)
ACR  A 801 (-4.3A)
ACR  A 801 (-3.3A)
ACR  A 801 (-4.0A)
ACR  A 801 (-2.7A)
ACR  A 801 (-3.7A)
ACR  A 801 (-3.1A)
ACR  A 801 (-3.9A)
ACR  A 801 (-2.8A)
ACR  A 801 ( 3.9A)
None
ACR  A 801 (-4.4A)
 0.34A 1agmA-6fhwA:
60.6		 1agmA-6fhwA:
10.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AGM_A_ACRA496_2
(GLUCOAMYLASE-471)		 6fhw GLUCOAMYLASE P
(Amorphotheca
resinae) 		4 / 5 TRP A 207
GLU A 208
LEU A 447
TRP A 449
 None
ACR  A 801 (-3.9A)
None
None
 0.27A 1agmA-6fhwA:
60.6		 1agmA-6fhwA:
10.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DDR_B_MTXB200_1
(DIHYDROFOLATE
REDUCTASE)		 6fhw GLUCOAMYLASE P
(Amorphotheca
resinae) 		5 / 12 ILE A 279
ALA A 282
LEU A 305
PHE A 308
LYS A 309
 None
 1.08A 1ddrB-6fhwA:
undetectable		 1ddrB-6fhwA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GAH_A_ACRA497_1
(GLUCOAMYLASE-471)		 6fhw GLUCOAMYLASE P
(Amorphotheca
resinae) 		11 / 12 TYR A  76
TRP A  80
ARG A  82
ASP A  83
TRP A 149
GLY A 150
GLU A 208
GLU A 209
TYR A 341
TRP A 347
GLU A 432
 ACR  A 801 (-4.3A)
ACR  A 801 (-3.3A)
ACR  A 801 (-4.0A)
ACR  A 801 (-2.7A)
ACR  A 801 (-3.7A)
ACR  A 801 (-3.1A)
ACR  A 801 (-3.9A)
ACR  A 801 (-3.9A)
ACR  A 801 ( 3.9A)
None
ACR  A 801 (-4.4A)
 0.29A 1gahA-6fhwA:
60.5		 1gahA-6fhwA:
10.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GAH_A_ACRA497_2
(GLUCOAMYLASE-471)		 6fhw GLUCOAMYLASE P
(Amorphotheca
resinae) 		5 / 6 ALA A  67
TRP A 207
ARG A 335
LEU A 447
TRP A 449
 ACR  A 801 (-3.5A)
None
ACR  A 801 (-2.8A)
None
None
 0.39A 1gahA-6fhwA:
60.5		 1gahA-6fhwA:
10.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG4_A_SAMA500_0
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 6fhw GLUCOAMYLASE P
(Amorphotheca
resinae) 		5 / 12 SER A 484
GLY A 196
GLY A 228
ALA A 245
VAL A 248
 None
 1.09A 1jg4A-6fhwA:
undetectable		 1jg4A-6fhwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LF9_A_ACRA700_1
(GLUCOAMYLASE)		 6fhw GLUCOAMYLASE P
(Amorphotheca
resinae) 		9 / 12 ALA A  67
TYR A  76
TRP A  80
ARG A  82
ASP A  83
GLU A 209
ARG A 335
TYR A 341
TRP A 449
 ACR  A 801 (-3.5A)
ACR  A 801 (-4.3A)
ACR  A 801 (-3.3A)
ACR  A 801 (-4.0A)
ACR  A 801 (-2.7A)
ACR  A 801 (-3.9A)
ACR  A 801 (-2.8A)
ACR  A 801 ( 3.9A)
None
 0.46A 1lf9A-6fhwA:
8.1		 1lf9A-6fhwA:
8.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LF9_A_ACRA700_1
(GLUCOAMYLASE)		 6fhw GLUCOAMYLASE P
(Amorphotheca
resinae) 		5 / 12 ALA A  67
TYR A  76
TRP A 149
GLU A 209
TYR A 341
 ACR  A 801 (-3.5A)
ACR  A 801 (-4.3A)
ACR  A 801 (-3.7A)
ACR  A 801 (-3.9A)
ACR  A 801 ( 3.9A)
 0.91A 1lf9A-6fhwA:
8.1		 1lf9A-6fhwA:
8.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LF9_A_ACRA700_1
(GLUCOAMYLASE)		 6fhw GLUCOAMYLASE P
(Amorphotheca
resinae) 		5 / 12 ASP A  83
GLN A 153
GLU A 209
ARG A 335
TYR A 341
 ACR  A 801 (-2.7A)
None
ACR  A 801 (-3.9A)
ACR  A 801 (-2.8A)
ACR  A 801 ( 3.9A)
 1.30A 1lf9A-6fhwA:
8.1		 1lf9A-6fhwA:
8.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LF9_A_ACRA700_2
(GLUCOAMYLASE)		 6fhw GLUCOAMYLASE P
(Amorphotheca
resinae) 		4 / 4 TRP A 207
GLU A 208
TRP A 347
LEU A 447
 None
ACR  A 801 (-3.9A)
None
None
 0.54A 1lf9A-6fhwA:
8.1		 1lf9A-6fhwA:
8.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LF9_B_ACRB701_1
(GLUCOAMYLASE)		 6fhw GLUCOAMYLASE P
(Amorphotheca
resinae) 		9 / 12 ALA A  67
TYR A  76
TRP A  80
ARG A  82
ASP A  83
GLU A 209
ARG A 335
TYR A 341
TRP A 347
 ACR  A 801 (-3.5A)
ACR  A 801 (-4.3A)
ACR  A 801 (-3.3A)
ACR  A 801 (-4.0A)
ACR  A 801 (-2.7A)
ACR  A 801 (-3.9A)
ACR  A 801 (-2.8A)
ACR  A 801 ( 3.9A)
None
 0.41A 1lf9B-6fhwA:
8.1		 1lf9B-6fhwA:
8.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LF9_B_ACRB701_1
(GLUCOAMYLASE)		 6fhw GLUCOAMYLASE P
(Amorphotheca
resinae) 		5 / 12 ALA A  67
TYR A  76
TRP A 149
GLU A 209
TYR A 341
 ACR  A 801 (-3.5A)
ACR  A 801 (-4.3A)
ACR  A 801 (-3.7A)
ACR  A 801 (-3.9A)
ACR  A 801 ( 3.9A)
 0.90A 1lf9B-6fhwA:
8.1		 1lf9B-6fhwA:
8.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LF9_B_ACRB701_1
(GLUCOAMYLASE)		 6fhw GLUCOAMYLASE P
(Amorphotheca
resinae) 		6 / 12 ASP A  83
GLN A 153
GLU A 209
ARG A 335
TYR A 341
TRP A 347
 ACR  A 801 (-2.7A)
None
ACR  A 801 (-3.9A)
ACR  A 801 (-2.8A)
ACR  A 801 ( 3.9A)
None
 1.29A 1lf9B-6fhwA:
8.1		 1lf9B-6fhwA:
8.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LF9_B_ACRB701_2
(GLUCOAMYLASE)		 6fhw GLUCOAMYLASE P
(Amorphotheca
resinae) 		4 / 4 TRP A 207
GLU A 208
LEU A 447
TRP A 449
 None
ACR  A 801 (-3.9A)
None
None
 0.60A 1lf9B-6fhwA:
8.1		 1lf9B-6fhwA:
8.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N2X_B_SAMB402_0
(S-ADENOSYL-METHYLTRA
NSFERASE MRAW)		 6fhw GLUCOAMYLASE P
(Amorphotheca
resinae) 		5 / 12 GLY A 134
GLU A 135
GLY A 132
GLY A 124
GLY A 203
 None
 0.84A 1n2xB-6fhwA:
undetectable		 1n2xB-6fhwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N49_D_RITD401_2
(PROTEASE)		 6fhw GLUCOAMYLASE P
(Amorphotheca
resinae) 		4 / 6 ASP A 155
GLY A 281
ILE A 283
ILE A 162
 None
 0.80A 1n49D-6fhwA:
undetectable		 1n49D-6fhwA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NH8_A_HISA289_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 6fhw GLUCOAMYLASE P
(Amorphotheca
resinae) 		4 / 5 ASP A 191
LEU A 133
ALA A 161
LEU A 164
 None
 1.10A 1nh8A-6fhwA:
undetectable		 1nh8A-6fhwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NW3_A_SAMA500_0
(HISTONE
METHYLTRANSFERASE
DOT1L)		 6fhw GLUCOAMYLASE P
(Amorphotheca
resinae) 		5 / 12 TYR A 583
GLY A 527
ALA A 540
LEU A 561
ASN A 587
 NAG  A 808 ( 4.9A)
None
None
None
NAG  A 808 (-1.9A)
 1.33A 1nw3A-6fhwA:
undetectable		 1nw3A-6fhwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RX8_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 6fhw GLUCOAMYLASE P
(Amorphotheca
resinae) 		5 / 12 ILE A 279
ALA A 282
LEU A 305
PHE A 308
LYS A 309
 None
 0.98A 1rx8A-6fhwA:
undetectable		 1rx8A-6fhwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ULV_A_ACRA3000_1
(GLUCODEXTRANASE)		 6fhw GLUCOAMYLASE P
(Amorphotheca
resinae) 		9 / 12 ALA A  67
TYR A  76
TRP A  80
ARG A  82
ASP A  83
GLU A 209
ARG A 335
TYR A 341
TRP A 347
 ACR  A 801 (-3.5A)
ACR  A 801 (-4.3A)
ACR  A 801 (-3.3A)
ACR  A 801 (-4.0A)
ACR  A 801 (-2.7A)
ACR  A 801 (-3.9A)
ACR  A 801 (-2.8A)
ACR  A 801 ( 3.9A)
None
 0.48A 1ulvA-6fhwA:
33.7		 1ulvA-6fhwA:
6.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ULV_A_ACRA3000_2
(GLUCODEXTRANASE)		 6fhw GLUCOAMYLASE P
(Amorphotheca
resinae) 		4 / 5 GLN A 153
GLU A 208
LEU A 349
TRP A 347
 None
ACR  A 801 (-3.9A)
None
None
 1.44A 1ulvA-6fhwA:
33.6		 1ulvA-6fhwA:
6.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ULV_A_ACRA3000_2
(GLUCODEXTRANASE)		 6fhw GLUCOAMYLASE P
(Amorphotheca
resinae) 		4 / 5 TRP A 207
GLU A 208
LEU A 447
TRP A 449
 None
ACR  A 801 (-3.9A)
None
None
 0.48A 1ulvA-6fhwA:
33.6		 1ulvA-6fhwA:
6.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F6D_A_ACRA995_1
(GLUCOAMYLASE GLU1)		 6fhw GLUCOAMYLASE P
(Amorphotheca
resinae) 		12 / 12 ALA A  67
TYR A  76
TRP A  80
ARG A  82
ASP A  83
TRP A 149
GLY A 150
GLU A 209
ARG A 335
TYR A 341
TRP A 347
GLU A 432
 ACR  A 801 (-3.5A)
ACR  A 801 (-4.3A)
ACR  A 801 (-3.3A)
ACR  A 801 (-4.0A)
ACR  A 801 (-2.7A)
ACR  A 801 (-3.7A)
ACR  A 801 (-3.1A)
ACR  A 801 (-3.9A)
ACR  A 801 (-2.8A)
ACR  A 801 ( 3.9A)
None
ACR  A 801 (-4.4A)
 0.35A 2f6dA-6fhwA:
45.3		 2f6dA-6fhwA:
10.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F6D_A_ACRA995_2
(GLUCOAMYLASE GLU1)		 6fhw GLUCOAMYLASE P
(Amorphotheca
resinae) 		4 / 4 TRP A 207
GLU A 208
LEU A 447
TRP A 449
 None
ACR  A 801 (-3.9A)
None
None
 0.28A 2f6dA-6fhwA:
45.3		 2f6dA-6fhwA:
10.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OTF_A_2TNA201_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 6fhw GLUCOAMYLASE P
(Amorphotheca
resinae) 		4 / 5 LEU A 252
ILE A 261
SER A 278
GLY A 281
 None
 0.72A 2otfA-6fhwA:
undetectable		 2otfA-6fhwA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XCT_H_CPFH1020_1
(DNA GYRASE SUBUNIT
B, DNA GYRASE
SUBUNIT A)		 6fhw GLUCOAMYLASE P
(Amorphotheca
resinae) 		3 / 3 ARG A 460
GLU A 356
SER A 294
 None
 0.92A 2xctD-6fhwA:
undetectable		 2xctD-6fhwA:
12.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKW_A_P1BA1478_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 6fhw GLUCOAMYLASE P
(Amorphotheca
resinae) 		4 / 7 LEU A  47
ILE A  91
ALA A 496
ILE A 187
 None
 0.73A 2xkwA-6fhwA:
undetectable		 2xkwA-6fhwA:
14.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_A_SALA1303_1
(LYSR-TYPE REGULATORY
PROTEIN)		 6fhw GLUCOAMYLASE P
(Amorphotheca
resinae) 		4 / 7 SER A 304
PHE A 215
ILE A 261
GLY A 281
 None
 0.96A 2y7kA-6fhwA:
undetectable		 2y7kA-6fhwA:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KM6_A_EAAA222_1
(GLUTATHIONE
S-TRANSFERASE P)		 6fhw GLUCOAMYLASE P
(Amorphotheca
resinae) 		5 / 10 GLY A 281
VAL A 333
ILE A 261
ASN A 277
GLY A 276
 None
 1.28A 3km6A-6fhwA:
2.1		 3km6A-6fhwA:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MJR_D_AC2D601_1
(DEOXYCYTIDINE KINASE)		 6fhw GLUCOAMYLASE P
(Amorphotheca
resinae) 		4 / 8 GLU A 209
ARG A 271
ARG A 335
ASP A 275
 ACR  A 801 (-3.9A)
None
ACR  A 801 (-2.8A)
None
 1.19A 3mjrD-6fhwA:
undetectable		 3mjrD-6fhwA:
14.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NMU_J_SAMJ228_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE
NOP5/NOP56 RELATED
PROTEIN)		 6fhw GLUCOAMYLASE P
(Amorphotheca
resinae) 		5 / 11 GLU A 432
TYR A 348
GLY A 334
ALA A 332
ASP A 339
 ACR  A 801 (-4.4A)
None
None
None
None
 1.21A 3nmuB-6fhwA:
undetectable
3nmuJ-6fhwA:
undetectable		 3nmuB-6fhwA:
undetectable
3nmuJ-6fhwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEL_B_QELB1_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE [NMDA]
RECEPTOR SUBUNIT
EPSILON-2)		 6fhw GLUCOAMYLASE P
(Amorphotheca
resinae) 		5 / 11 THR A 516
ARG A 552
LEU A 554
ALA A 605
THR A 601
 None
NAG  A 815 ( 4.0A)
None
NAG  A 815 (-3.4A)
None
 1.29A 3qelA-6fhwA:
undetectable
3qelB-6fhwA:
undetectable		 3qelA-6fhwA:
13.16
3qelB-6fhwA:
11.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_A_SUEA1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 6fhw GLUCOAMYLASE P
(Amorphotheca
resinae) 		4 / 4 PHE A 286
TYR A 359
ILE A 261
LEU A 297
 None
 1.47A 3sudA-6fhwA:
undetectable		 3sudA-6fhwA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TI1_A_B49A299_1
(CYCLIN-DEPENDENT
KINASE 2)		 6fhw GLUCOAMYLASE P
(Amorphotheca
resinae) 		5 / 9 ILE A 350
ALA A 354
PHE A 357
ASP A 275
LEU A 311
 None
 1.32A 3ti1A-6fhwA:
undetectable		 3ti1A-6fhwA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V5V_A_ACTA511_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 6fhw GLUCOAMYLASE P
(Amorphotheca
resinae) 		4 / 4 ASN A 277
PHE A 215
SER A 214
GLN A 219
 None
 1.39A 3v5vA-6fhwA:
undetectable		 3v5vA-6fhwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AE1_A_NCAA1536_0
(DIPHTHERIA TOXIN)		 6fhw GLUCOAMYLASE P
(Amorphotheca
resinae) 		4 / 6 HIS A 111
GLY A 497
ALA A 496
GLU A 107
 None
 0.86A 4ae1A-6fhwA:
undetectable		 4ae1A-6fhwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8Y_A_VK3A202_1
(NADPH QUINONE
OXIDOREDUCTASE)		 6fhw GLUCOAMYLASE P
(Amorphotheca
resinae) 		4 / 5 ARG A 316
TYR A 416
TYR A 412
LEU A 358
 None
 0.93A 4f8yA-6fhwA:
undetectable
4f8yB-6fhwA:
undetectable		 4f8yA-6fhwA:
18.82
4f8yB-6fhwA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8Y_B_VK3B202_1
(NADPH QUINONE
OXIDOREDUCTASE)		 6fhw GLUCOAMYLASE P
(Amorphotheca
resinae) 		4 / 6 ARG A 316
TYR A 416
TYR A 412
LEU A 358
 None
 1.18A 4f8yA-6fhwA:
undetectable
4f8yB-6fhwA:
undetectable		 4f8yA-6fhwA:
18.82
4f8yB-6fhwA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8Y_C_VK3C202_1
(NADPH QUINONE
OXIDOREDUCTASE)		 6fhw GLUCOAMYLASE P
(Amorphotheca
resinae) 		4 / 7 ARG A 316
TYR A 416
TYR A 412
LEU A 358
 None
 0.97A 4f8yC-6fhwA:
undetectable
4f8yD-6fhwA:
undetectable		 4f8yC-6fhwA:
18.82
4f8yD-6fhwA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEU_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 6fhw GLUCOAMYLASE P
(Amorphotheca
resinae) 		4 / 8 ASP A 339
ASP A 205
GLU A 432
ASP A 275
 None
None
ACR  A 801 (-4.4A)
None
 1.02A 4feuD-6fhwA:
undetectable		 4feuD-6fhwA:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 6fhw GLUCOAMYLASE P
(Amorphotheca
resinae) 		4 / 7 ASP A 339
ASP A 205
GLU A 432
ASP A 275
 None
None
ACR  A 801 (-4.4A)
None
 1.03A 4fevB-6fhwA:
undetectable		 4fevB-6fhwA:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEW_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 6fhw GLUCOAMYLASE P
(Amorphotheca
resinae) 		4 / 7 ASP A 339
ASP A 205
GLU A 432
ASP A 275
 None
None
ACR  A 801 (-4.4A)
None
 1.06A 4fewB-6fhwA:
undetectable		 4fewB-6fhwA:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 6fhw GLUCOAMYLASE P
(Amorphotheca
resinae) 		4 / 8 ASP A 339
ASP A 205
GLU A 432
ASP A 275
 None
None
ACR  A 801 (-4.4A)
None
 1.06A 4gkhD-6fhwA:
undetectable		 4gkhD-6fhwA:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOE_F_TR6F101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B
E-SITE DNA2)		 6fhw GLUCOAMYLASE P
(Amorphotheca
resinae) 		4 / 6 ARG A 154
GLY A 130
ASP A 129
GLY A 124
 None
 0.96A 4koeA-6fhwA:
undetectable
4koeB-6fhwA:
undetectable
4koeC-6fhwA:
undetectable		 4koeA-6fhwA:
9.68
4koeB-6fhwA:
9.68
4koeC-6fhwA:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KRH_B_SAMB900_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE
2)		 6fhw GLUCOAMYLASE P
(Amorphotheca
resinae) 		4 / 4 ILE A  35
SER A  33
ASP A 414
ASP A 407
 None
 0.95A 4krhB-6fhwA:
undetectable		 4krhB-6fhwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PSY_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 6fhw GLUCOAMYLASE P
(Amorphotheca
resinae) 		5 / 12 ILE A 279
ALA A 282
LEU A 305
ALA A 306
PHE A 308
 None
 0.83A 4psyA-6fhwA:
undetectable		 4psyA-6fhwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_A_1LDA501_0
(CYTOSINE DEAMINASE)		 6fhw GLUCOAMYLASE P
(Amorphotheca
resinae) 		5 / 12 HIS A 301
LEU A 252
ILE A 261
LEU A 249
SER A 294
 None
 1.26A 4r88A-6fhwA:
undetectable		 4r88A-6fhwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_B_1LDB501_0
(CYTOSINE DEAMINASE)		 6fhw GLUCOAMYLASE P
(Amorphotheca
resinae) 		5 / 12 HIS A 301
LEU A 252
ILE A 261
LEU A 249
SER A 294
 None
 1.28A 4r88B-6fhwA:
undetectable		 4r88B-6fhwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_C_1LDC501_0
(CYTOSINE DEAMINASE)		 6fhw GLUCOAMYLASE P
(Amorphotheca
resinae) 		5 / 12 HIS A 301
LEU A 252
ILE A 261
LEU A 249
SER A 294
 None
 1.29A 4r88C-6fhwA:
undetectable		 4r88C-6fhwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_D_1LDD501_0
(CYTOSINE DEAMINASE)		 6fhw GLUCOAMYLASE P
(Amorphotheca
resinae) 		5 / 12 HIS A 301
LEU A 252
ILE A 261
LEU A 249
SER A 294
 None
 1.27A 4r88D-6fhwA:
undetectable		 4r88D-6fhwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_E_1LDE501_0
(CYTOSINE DEAMINASE)		 6fhw GLUCOAMYLASE P
(Amorphotheca
resinae) 		5 / 12 HIS A 301
LEU A 252
ILE A 261
LEU A 249
SER A 294
 None
 1.29A 4r88E-6fhwA:
undetectable		 4r88E-6fhwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_F_1LDF502_0
(CYTOSINE DEAMINASE)		 6fhw GLUCOAMYLASE P
(Amorphotheca
resinae) 		5 / 12 HIS A 301
LEU A 252
ILE A 261
LEU A 249
SER A 294
 None
 1.29A 4r88F-6fhwA:
undetectable		 4r88F-6fhwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URO_B_NOVB2000_1
(DNA GYRASE SUBUNIT B)		 6fhw GLUCOAMYLASE P
(Amorphotheca
resinae) 		5 / 12 GLU A 227
ARG A 223
PRO A 466
GLN A 459
ILE A  96
 None
 1.31A 4uroB-6fhwA:
undetectable		 4uroB-6fhwA:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5O_A_IPHA906_0
(PROTEIN ARGONAUTE-2)		 6fhw GLUCOAMYLASE P
(Amorphotheca
resinae) 		4 / 5 PRO A  58
VAL A  57
ALA A  60
PHE A  77
 None
 1.12A 4w5oA-6fhwA:
undetectable		 4w5oA-6fhwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WS1_A_URFA301_1
(URACIL-DNA
GLYCOSYLASE)		 6fhw GLUCOAMYLASE P
(Amorphotheca
resinae) 		4 / 8 GLY A 241
GLN A 244
TYR A 198
SER A 193
 None
 0.98A 4ws1A-6fhwA:
undetectable		 4ws1A-6fhwA:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XJE_A_TOYA202_1
(AADB)		 6fhw GLUCOAMYLASE P
(Amorphotheca
resinae) 		4 / 8 ASP A 289
ASP A 287
GLU A 227
ILE A 162
 None
 1.01A 4xjeA-6fhwA:
undetectable		 4xjeA-6fhwA:
24.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z2E_H_TR6H101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
SYMMETRIZED E-SITE
DNA)		 6fhw GLUCOAMYLASE P
(Amorphotheca
resinae) 		3 / 5 GLY A 330
GLY A 328
GLU A 327
 None
 0.48A 4z2eA-6fhwA:
undetectable
4z2eD-6fhwA:
undetectable		 4z2eA-6fhwA:
9.69
4z2eD-6fhwA:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 6fhw GLUCOAMYLASE P
(Amorphotheca
resinae) 		4 / 5 PRO A  58
VAL A  57
ALA A  60
PHE A  77
 None
 1.16A 4z4cA-6fhwA:
undetectable		 4z4cA-6fhwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4D_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 6fhw GLUCOAMYLASE P
(Amorphotheca
resinae) 		4 / 5 PRO A  58
VAL A  57
ALA A  60
PHE A  77
 None
 1.13A 4z4dA-6fhwA:
undetectable		 4z4dA-6fhwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4E_A_IPHA906_0
(PROTEIN ARGONAUTE-2)		 6fhw GLUCOAMYLASE P
(Amorphotheca
resinae) 		4 / 5 PRO A  58
VAL A  57
ALA A  60
PHE A  77
 None
 1.13A 4z4eA-6fhwA:
undetectable		 4z4eA-6fhwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZB_C_ACTC401_0
(PROTON-GATED ION
CHANNEL)		 6fhw GLUCOAMYLASE P
(Amorphotheca
resinae) 		4 / 7 ILE A 509
PHE A 511
VAL A 592
ILE A 567
 None
 0.92A 4zzbC-6fhwA:
undetectable
4zzbD-6fhwA:
undetectable		 4zzbC-6fhwA:
undetectable
4zzbD-6fhwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B2S_A_ACTA107_0
(CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
GUIDE RNA)		 6fhw GLUCOAMYLASE P
(Amorphotheca
resinae) 		3 / 3 VAL A 331
THR A 312
ARG A 316
 None
 0.73A 5b2sB-6fhwA:
2.1		 5b2sB-6fhwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B2T_A_ACTA108_0
(CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
GUIDE RNA)		 6fhw GLUCOAMYLASE P
(Amorphotheca
resinae) 		3 / 3 VAL A 331
THR A 312
ARG A 316
 None
 0.77A 5b2tB-6fhwA:
2.3		 5b2tB-6fhwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BS8_H_MFXH101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 6fhw GLUCOAMYLASE P
(Amorphotheca
resinae) 		4 / 7 ALA A 367
ARG A 223
GLY A 470
GLU A 227
 None
 0.96A 5bs8A-6fhwA:
undetectable
5bs8B-6fhwA:
undetectable
5bs8C-6fhwA:
undetectable		 5bs8A-6fhwA:
15.97
5bs8B-6fhwA:
14.23
5bs8C-6fhwA:
15.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTA_H_MFXH101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 6fhw GLUCOAMYLASE P
(Amorphotheca
resinae) 		4 / 6 ARG A 223
GLY A 470
THR A 166
GLU A 227
 None
 0.99A 5btaA-6fhwA:
undetectable
5btaB-6fhwA:
undetectable
5btaC-6fhwA:
undetectable		 5btaA-6fhwA:
15.97
5btaB-6fhwA:
14.23
5btaC-6fhwA:
15.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTC_G_CPFG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 6fhw GLUCOAMYLASE P
(Amorphotheca
resinae) 		4 / 6 ARG A 223
GLY A 470
THR A 166
GLU A 227
 None
 0.96A 5btcA-6fhwA:
undetectable
5btcC-6fhwA:
undetectable
5btcD-6fhwA:
undetectable		 5btcA-6fhwA:
15.97
5btcC-6fhwA:
15.97
5btcD-6fhwA:
14.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTC_G_CPFG102_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 6fhw GLUCOAMYLASE P
(Amorphotheca
resinae) 		4 / 6 ARG A 223
GLY A 470
THR A 166
GLU A 227
 None
 0.97A 5btcA-6fhwA:
undetectable
5btcB-6fhwA:
undetectable
5btcC-6fhwA:
undetectable		 5btcA-6fhwA:
15.97
5btcB-6fhwA:
14.23
5btcC-6fhwA:
15.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTC_G_CPFG102_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 6fhw GLUCOAMYLASE P
(Amorphotheca
resinae) 		4 / 6 SER A 214
ARG A 151
GLY A 134
GLU A 135
 None
 1.10A 5btcA-6fhwA:
undetectable
5btcB-6fhwA:
undetectable
5btcC-6fhwA:
undetectable		 5btcA-6fhwA:
15.97
5btcB-6fhwA:
14.23
5btcC-6fhwA:
15.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTD_E_GFNE101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 6fhw GLUCOAMYLASE P
(Amorphotheca
resinae) 		4 / 7 ALA A 367
ARG A 223
GLY A 470
GLU A 227
 None
 0.94A 5btdA-6fhwA:
undetectable
5btdB-6fhwA:
undetectable
5btdC-6fhwA:
undetectable		 5btdA-6fhwA:
15.97
5btdB-6fhwA:
14.23
5btdC-6fhwA:
15.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTD_G_GFNG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 6fhw GLUCOAMYLASE P
(Amorphotheca
resinae) 		4 / 7 ALA A 367
ARG A 223
GLY A 470
GLU A 227
 None
 0.91A 5btdA-6fhwA:
undetectable
5btdC-6fhwA:
undetectable
5btdD-6fhwA:
undetectable		 5btdA-6fhwA:
15.97
5btdC-6fhwA:
15.97
5btdD-6fhwA:
14.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTG_E_LFXE101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 6fhw GLUCOAMYLASE P
(Amorphotheca
resinae) 		5 / 6 ALA A 367
ARG A 223
GLY A 470
THR A 166
GLU A 227
 None
 1.43A 5btgA-6fhwA:
undetectable
5btgB-6fhwA:
undetectable
5btgC-6fhwA:
undetectable		 5btgA-6fhwA:
15.97
5btgB-6fhwA:
14.23
5btgC-6fhwA:
15.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K50_A_ACTA1403_0
(L-THREONINE
3-DEHYDROGENASE)		 6fhw GLUCOAMYLASE P
(Amorphotheca
resinae) 		4 / 5 SER A 508
VAL A 507
GLY A 597
ALA A 599
 None
 1.01A 5k50A-6fhwA:
undetectable		 5k50A-6fhwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T7B_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 6fhw GLUCOAMYLASE P
(Amorphotheca
resinae) 		4 / 6 PRO A  58
VAL A  57
ALA A  60
PHE A  77
 None
 1.13A 5t7bA-6fhwA:
undetectable		 5t7bA-6fhwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_S_PCFS603_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 8
CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL)		 6fhw GLUCOAMYLASE P
(Amorphotheca
resinae) 		4 / 7 GLN A 108
GLY A  63
PHE A  64
VAL A  66
 None
 1.01A 6hu9S-6fhwA:
undetectable
6hu9q-6fhwA:
0.9		 6hu9S-6fhwA:
undetectable
6hu9q-6fhwA:
undetectable